Product References
An engineered Sox17 induces somatic to neural stem cell fate transitions independently from pluripotency reprogramming.
Science advances
Weng M,Hu H,Graus MS,Tan DS,Gao Y,Ren S,Ho DHH,Langer J,Holzner M,Huang Y,Ling GS,Lai CSW,Francois M,Jauch R
AF-120-05ET was used in In vitro experiments to report iNSC reprogramming from embryonic and aged mouse fibroblasts as well as from human blood using an engineered Sox17 (eSox17FNV).
Fri Aug 25 00:00:00 EDT 2023
Accelerated differentiation of human induced pluripotent stem cells into regionally specific dorsal and ventral spinal neural progenitor cells for application in spinal cord therapeutics.
Frontiers in neuroscience
Huntemer-Silveira A,Malone D,Frie A,Walsh P,Parr AM
AF-120-05ET was used in In vitro experiments to describe here the production of a diverse population of both ventral spinal and dorsal horn progenitor cells.
Sat Feb 10 00:00:00 EST 2024
Generation of Human Pluripotent Stem Cell-Derived Polarized Hepatocytes.
Current protocols
Bushweller L,Zhao Y,Zhang F,Wu X
AF-120-05ET was used in Cell Culture to describe protocols to generate hPSC-derived polarized HLCs (pol-HLCs), which feature clearly defined basolateral and apical membranes separated by tight junctions and to assay the pol-HLCs for basic hepatic functions and polarized hepatic characteristics.
Sat Jan 01 00:00:00 EST 2022
High-throughput screening in postimplantation haploid epiblast stem cells reveals Hs3st3b1 as a modulator for reprogramming.
Stem cells translational medicine
Gao Q,Zhang W,Zhao Y,Tian Y,Wang Y,Zhang J,Geng M,Xu M,Yao C,Wang H,Li L,Liu Y,Shuai L
Sat May 01 00:00:00 EDT 2021
HES1 protein oscillations are necessary for neural stem cells to exit from quiescence.
iScience
Marinopoulou E,Biga V,Sabherwal N,Miller A,Desai J,Adamson AD,Papalopulu N
Fri Oct 22 00:00:00 EDT 2021
TRPC5 Channel Inhibition Protects Podocytes in Puromycin-Aminonucleoside Induced Nephrosis Models.
Frontiers in medicine
Zhou Y,Kim C,Pablo JLB,Zhang F,Jung JY,Xiao L,Bazua-Valenti S,Emani M,Hopkins CR,Weins A,Greka A
AF-120-05ET was used in In vitro experiments to reveal the relevance of TRPC5 channel inhibition in puromycin-aminonucleoside induced nephrosis models, highlighting the potential of this therapeutic strategy for patients.
Wed Jun 07 00:00:00 EDT 2023
An airway organoid-based screen identifies a role for the HIF1α-glycolysis axis in SARS-CoV-2 infection.
Cell reports
Duan X,Tang X,Nair MS,Zhang T,Qiu Y,Zhang W,Wang P,Huang Y,Xiang J,Wang H,Schwartz RE,Ho DD,Evans T,Chen S
Tue Nov 09 00:00:00 EST 2021
Keratinocytes from Gorlin Syndrome-induced pluripotent stem cells are resistant against UV radiation.
Medical molecular morphology
Morita N,Onodera S,Nakamura Y,Nakamura T,Takahashi SI,Nomura T,Azuma T
AF-120-05ET was used in Cell Culture to investigate the expression of Hh target molecules keratinocytes from Gorlin syndrome patients.
Tue Jun 01 00:00:00 EDT 2021
LRIG1 is a gatekeeper to exit from quiescence in adult neural stem cells.
Nature communications
Marqués-Torrejón MÁ,Williams CAC,Southgate B,Alfazema N,Clements MP,Garcia-Diaz C,Blin C,Arranz-Emparan N,Fraser J,Gammoh N,Parrinello S,Pollard SM
Mon May 10 00:00:00 EDT 2021
Neurobiological roots of psychopathy.
Molecular psychiatry
Tiihonen J,Koskuvi M,Lähteenvuo M,Virtanen PLJ,Ojansuu I,Vaurio O,Gao Y,Hyötyläinen I,Puttonen KA,Repo-Tiihonen E,Paunio T,Rautiainen MR,Tyni S,Koistinaho J,Lehtonen Š
Tue Dec 01 00:00:00 EST 2020
Accelerated differentiation of human pluripotent stem cells into neural lineages via an early intermediate ectoderm population.
Stem cells (Dayton, Ohio)
Walsh P,Truong V,Nayak S,Saldías Montivero M,Low WC,Parr AM,Dutton JR
Sun Nov 01 00:00:00 EDT 2020
Self-Organizing Human Induced Pluripotent Stem Cell Hepatocyte 3D Organoids Inform the Biology of the Pleiotropic TRIB1 Gene.
Hepatology communications
Abbey D,Elwyn S,Hand NJ,Musunuru K,Rader DJ
Tue Sep 01 00:00:00 EDT 2020
Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines.
Nature communications
Boon R,Kumar M,Tricot T,Elia I,Ordovas L,Jacobs F,One J,De Smedt J,Eelen G,Bird M,Roelandt P,Doglioni G,Vriens K,Rossi M,Vazquez MA,Vanwelden T,Chesnais F,El Taghdouini A,Najimi M,Sokal E,Cassiman D,Snoeys J,Monshouwer M,Hu WS,Lange C,Carmeliet P,Fendt SM,Verfaillie CM
Fri Mar 13 00:00:00 EDT 2020
Human iPSC-derived mature microglia retain their identity and functionally integrate in the chimeric mouse brain.
Nature communications
Xu R,Li X,Boreland AJ,Posyton A,Kwan K,Hart RP,Jiang P
Fri Mar 27 00:00:00 EDT 2020
Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner.
Theranostics
Li J,Yang KY,Tam RCY,Chan VW,Lan HY,Hori S,Zhou B,Lui KO
AF-120-05ET was used in Cell Culture to investigate the role of Treg in neonatal heart regeneration in mice.
Fri Aug 14 00:00:00 EDT 2020
Long noncoding RNA ANCR inhibits the differentiation of mesenchymal stem cells toward definitive endoderm by facilitating the association of PTBP1 with ID2.
Cell death & disease
Li J,Yang Y,Fan J,Xu H,Fan L,Li H,Zhao RC
Mon Jun 24 00:00:00 EDT 2019
Functionalization of Brain Region-specific Spheroids with Isogenic Microglia-like Cells.
Scientific reports
Song L,Yuan X,Jones Z,Vied C,Miao Y,Marzano M,Hua T,Sang QA,Guan J,Ma T,Zhou Y,Li Y
Tue Jul 30 00:00:00 EDT 2019
Exosomes Derived from Human Induced Pluripotent Stem Cells-Endothelia Cells Promotes Postnatal Angiogenesis in Mice Bearing Ischemic Limbs.
International journal of biological sciences
Ye M,Ni Q,Qi H,Qian X,Chen J,Guo X,Li M,Zhao Y,Xue G,Deng H,Zhang L
AF-120-05ET was used in In vitro experiments to demonstrate exosomes derived from hiPS-ECs expressing miR-199b-5p promote angiogenesis in a mouse model bearing ischemic limbs through Jagged-1-dependent upregulation of VEGFR2 in HUVECs.
Mon Dec 16 00:00:00 EST 2019
Intrinsic Immunity Shapes Viral Resistance of Stem Cells.
Cell
Wu X,Dao Thi VL,Huang Y,Billerbeck E,Saha D,Hoffmann HH,Wang Y,Silva LAV,Sarbanes S,Sun T,Andrus L,Yu Y,Quirk C,Li M,MacDonald MR,Schneider WM,An X,Rosenberg BR,Rice CM
Thu Jan 25 00:00:00 EST 2018
Long Noncoding RNA uc001pwg.1 Is Downregulated in Neointima in Arteriovenous Fistulas and Mediates the Function of Endothelial Cells Derived from Pluripotent Stem Cells.
Stem cells international
Lv L,Qi H,Guo X,Ni Q,Yan Z,Zhang L
AF-120-05ET was used in In vitro experiments to represent the first effort of identifying a novel candidate lncRNA for modulating the function of iPSC-ECs, which may facilitate the improvement of stem cell-based therapies for AVF failure.
Tue Sep 29 00:00:00 EDT 2020
The Axolotl Fibula as a Model for the Induction of Regeneration across Large Segment Defects in Long Bones of the Extremities.
PloS one
Chen X,Song F,Jhamb D,Li J,Bottino MC,Palakal MJ,Stocum DL
AF-120-05ET was used in In vitro experiments to study the ability of the axolotl (Ambystoma mexicanum) fibula to regenerate across segment defects of different size in the absence of intervention or after implant of a unique 8-braid pig small intestine submucosa (SIS) scaffold, with or without incorporated growth factor combinations or tissue protein extract.
Mon Apr 25 00:00:00 EDT 2016
The Axolotl Fibula as a Model for the Induction of Regeneration across Large Segment Defects in Long Bones of the Extremities.
PloS one
Chen X,Song F,Jhamb D,Li J,Bottino MC,Palakal MJ,Stocum DL
AF-120-05ET was used in In vitro experiments to study the ability of the axolotl (Ambystoma mexicanum) fibula to regenerate across segment defects of different size in the absence of intervention or after implant of a unique 8-braid pig small intestine submucosa (SIS) scaffold, with or without incorporated growth factor combinations or tissue protein extract.
Mon Apr 25 00:00:00 EDT 2016
Noggin recruits mesoderm progenitors from the dorsal aorta to a skeletal myogenic fate.
Developmental biology
Ugarte G,Cappellari O,Perani L,Pistocchi A,Cossu G
Tue May 01 00:00:00 EDT 2012
Activation of the canonical bone morphogenetic protein (BMP) pathway during lung morphogenesis and adult lung tissue repair.
PloS one
Sountoulidis A,Stavropoulos A,Giaglis S,Apostolou E,Monteiro R,Chuva de Sousa Lopes SM,Chen H,Stripp BR,Mummery C,Andreakos E,Sideras P
Wed May 15 00:00:00 EDT 2013
Activin A promotes neuronal differentiation of cerebrocortical neural progenitor cells.
PloS one
Rodríguez-Martínez G,Molina-Hernández A,Velasco I
Tue Jan 29 00:00:00 EST 2013
Fstl1 antagonizes BMP signaling and regulates ureter development.
PloS one
Xu J,Qi X,Gong J,Yu M,Zhang F,Sha H,Gao X
Fri Jul 27 00:00:00 EDT 2012
Angiopoietin-1 promotes endothelial differentiation from embryonic stem cells and induced pluripotent stem cells.
Blood
Joo HJ,Kim H,Park SW,Cho HJ,Kim HS,Lim DS,Chung HM,Kim I,Han YM,Koh GY
Thu Aug 25 00:00:00 EDT 2011
Inducible cassette exchange: a rapid and efficient system enabling conditional gene expression in embryonic stem and primary cells.
Stem cells (Dayton, Ohio)
Iacovino M,Bosnakovski D,Fey H,Rux D,Bajwa G,Mahen E,Mitanoska A,Xu Z,Kyba M
Sat Oct 01 00:00:00 EDT 2011
