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This peptide corresponds to 15 amino acids near the carboxy terminus of human PIKE.
PEP-0184 can be used as a blocking peptide with polyclonal antibody PA5-20065.
The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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Protein Aliases: AGAP-2; Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 2; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2; centaurin gamma1; centaurin, gamma 1; Centaurin-gamma-1; Cnt-g1; FLJ16430; GGAP2; GTP-binding and GTPase activating protein 2; GTP-binding and GTPase-activating protein 2; Phosphatidylinositol 3-kinase enhancer; phosphatidylinositol-3-kinase enhancer; phosphoinositide 3-kinase enhancer; PIKE
Gene Aliases: AGAP2; CENTG1; GGAP2; KIAA0167; PIKE
UniProt ID: (Human) Q99490
Entrez Gene ID: (Human) 116986
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