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Product Details
RP-43142
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Published species
Not Applicable
Molecular weight
340 kDa
Class
Native
Type
Protein
Conjugate
Form
Liquid
Concentration
4.3 mg/mL
Purification
Affinity chromatography
Storage buffer
0.01M sodium phosphate/0.01M sodium citrate, pH 7.3
Contains
no preservative
Storage conditions
-80° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Dry ice
Product Specific Information
RP-43142 contains native human Fibrinogen protein.
RP-43142 may be used as a positive control in many immunological assays.
The product is of human blood/plasma origin. Although the starting material was tested prior to initiation of the manufacturing process, and was found negative or nonreactive for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II, extreme caution should be used when handling this material as there is a margin of error in all tests.
This product is to be used for IN VITRO research purposes only, and is not intended for clinical or diagnostic use!
Target Information
Fibrinogen, the precursor of fibrin, is the coagulable protein in the blood plasma of vertebrates. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. Fibrinogen consists as a dimer of 3 pairs of non-identical chains FGA, FGB, and FGG that are cross-linked by disulfide bonds in their N-terminal segments. The molecule has 2 terminal D domains and one central E domain, all three domains are separated when fibrinogen is degradated by plasmin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, afibrinogenemia, and renal amyloidosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: epididymis secretory sperm binding protein Li 78p; fibg; Fibrinogen alpha chain; Fibrinogen beta chain; Fibrinogen gamma chain; fibrinogen, A alpha polypeptide; fibrinogen, B beta polypeptide; fibrinogen, gamma polypeptide; MGC119422; MGC119423; MGC119425; testicular tissue protein Li 70
Gene Aliases: FGA; FGB; FGG; Fib2; HEL-S-78p; PRO2061
UniProt ID: (Human) P02671, (Human) P02675, (Human) A8K057
Entrez Gene ID: (Human) 2243, (Human) 2244, (Human) 2266
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