Product References
A plant-derived glucocorticoid receptor modulator with potency to attenuate the side effects of glucocorticoid therapy.
British journal of pharmacology
Wang Y,Gao J,Yu Y,Zhou L,Wang M,Xue W,Liu B,Wu X,Wu X,Gao H,Shen Y,Xu Q
200-01A was used in In vitro experiments to reveal that CA-e is a novel GR modulator with strong potency to attenuate the side effects of GC therapy and can be used as a potential molecular tool for deciphering GR signalling.
Sun Jan 01 00:00:00 EST 2023
Charge-Based Multiarm Avidin Nanoconstruct as a Platform Technology for Applications in Drug Delivery.
Methods in molecular biology (Clifton, N.J.)
He T,Zhang C,Bajpayee AG
200-01A was used in Cell Culture to describe methods to control hydrolysis rates of ester linkers to enable sustained (and tunable) drug release rates in therapeutic doses.
Wed Mar 30 00:00:00 EDT 2022
Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes.
Cell
Karki R,Sharma BR,Tuladhar S,Williams EP,Zalduondo L,Samir P,Zheng M,Sundaram B,Banoth B,Malireddi RKS,Schreiner P,Neale G,Vogel P,Webby R,Jonsson CB,Kanneganti TD
Thu Jan 07 00:00:00 EST 2021
Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes.
Cell
Karki R,Sharma BR,Tuladhar S,Williams EP,Zalduondo L,Samir P,Zheng M,Sundaram B,Banoth B,Malireddi RKS,Schreiner P,Neale G,Vogel P,Webby R,Jonsson CB,Kanneganti TD
Thu Jan 07 00:00:00 EST 2021
Spatially organized multicellular immune hubs in human colorectal cancer.
Cell
Pelka K,Hofree M,Chen JH,Sarkizova S,Pirl JD,Jorgji V,Bejnood A,Dionne D,Ge WH,Xu KH,Chao SX,Zollinger DR,Lieb DJ,Reeves JW,Fuhrman CA,Hoang ML,Delorey T,Nguyen LT,Waldman J,Klapholz M,Wakiro I,Cohen O,Albers J,Smillie CS,Cuoco MS,Wu J,Su MJ,Yeung J,Vijaykumar B,Magnuson AM,Asinovski N,Moll T,Goder-Reiser MN,Applebaum AS,Brais LK,DelloStritto LK,Denning SL,Phillips ST,Hill EK,Meehan JK,Frederick DT,Sharova T,Kanodia A,Todres EZ,Jané-Valbuena J,Biton M,Izar B,Lambden CD,Clancy TE,Bleday R,Melnitchouk N,Irani J,Kunitake H,Berger DL,Srivastava A,Hornick JL,Ogino S,Rotem A,Vigneau S,Johnson BE,Corcoran RB,Sharpe AH,Kuchroo VK,Ng K,Giannakis M,Nieman LT,Boland GM,Aguirre AJ,Anderson AC,Rozenblatt-Rosen O,Regev A,Hacohen N
Thu Sep 02 00:00:00 EDT 2021
Matrix stiffness drives stromal autophagy and promotes formation of a protumorigenic niche.
Proceedings of the National Academy of Sciences of the United States of America
Hupfer A,Brichkina A,Koeniger A,Keber C,Denkert C,Pfefferle P,Helmprobst F,Pagenstecher A,Visekruna A,Lauth M
Tue Oct 05 00:00:00 EDT 2021
Matrix stiffness drives stromal autophagy and promotes formation of a protumorigenic niche.
Proceedings of the National Academy of Sciences of the United States of America
Hupfer A,Brichkina A,Koeniger A,Keber C,Denkert C,Pfefferle P,Helmprobst F,Pagenstecher A,Visekruna A,Lauth M
Tue Oct 05 00:00:00 EDT 2021
Protein kinase C eta is activated in reactive astrocytes of an Alzheimer's disease mouse model: Evidence for its immunoregulatory function in primary astrocytes.
Glia
Muraleedharan A,Rotem-Dai N,Strominger I,Anto NP,Isakov N,Monsonego A,Livneh E
Mon Mar 01 00:00:00 EST 2021
FABP4 deactivates NF-κB-IL1α pathway by ubiquitinating ATPB in tumor-associated macrophages and promotes neuroblastoma progression.
Clinical and translational medicine
Miao L,Zhuo Z,Tang J,Huang X,Liu J,Wang HY,Xia H,He J
Thu Apr 01 00:00:00 EDT 2021
MiR-193b-3p-ERBB4 axis regulates psoriasis pathogenesis via modulating cellular proliferation and inflammatory-mediator production of keratinocytes.
Cell death & disease
Huang C,Zhong W,Ren X,Huang X,Li Z,Chen C,Jiang B,Chen Z,Jian X,Yang L,Liu X,Huang H,Shen C,Chen X,Dou X,Yu B
Tue Oct 19 00:00:00 EDT 2021
Inflammatory Cell Death, PANoptosis, Mediated by Cytokines in Diverse Cancer Lineages Inhibits Tumor Growth.
ImmunoHorizons
Malireddi RKS,Karki R,Sundaram B,Kancharana B,Lee S,Samir P,Kanneganti TD
200-01A was used in Cell Culture to investigate correlations between cytokine expression and mortality.
Wed Jul 21 00:00:00 EDT 2021
RPL22 Overexpression Promotes Psoriasis-Like Lesion by Inducing Keratinocytes Abnormal Biological Behavior.
Frontiers in immunology
Zeng J,Zhang Y,Zhang H,Zhang Y,Gao L,Tong X,Xie Y,Hu Q,Chen C,Ding S,Lu J
200-01A was used in Sample Preparation to study the specific mechanism leading to the abnormal biological behavior of keratinocytes and suggest that RPL22 regulates keratinocytes abnormal biological behavior and contributes to the development of psoriatic phenotypes.
Mon Dec 13 00:00:00 EST 2021
Iron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy.
Nature communications
Fisher AL,Sangkhae V,Balušíková K,Palaskas NJ,Ganz T,Nemeth E
Tue Jun 29 00:00:00 EDT 2021
Necroptosis Underlies Neutrophilic Inflammation Associated with the Chronic Rhinosinusitis with Nasal Polyps (CRSwNP).
Journal of inflammation research
Xie Y,Li M,Chen K,Zhu H,Tang M,Zhou C,Zheng Y,Wen J,Han M,Zhang J,Zhao K,Xiao H,Li H
200-01A was used in Enzyme-linked immunosorbent assay to investigate necroptosis in chronic rhinosinusitis with nasal polyps.
Tue Apr 26 00:00:00 EDT 2022
The Global Phosphorylation Landscape of SARS-CoV-2 Infection.
Cell
Bouhaddou M,Memon D,Meyer B,White KM,Rezelj VV,Correa Marrero M,Polacco BJ,Melnyk JE,Ulferts S,Kaake RM,Batra J,Richards AL,Stevenson E,Gordon DE,Rojc A,Obernier K,Fabius JM,Soucheray M,Miorin L,Moreno E,Koh C,Tran QD,Hardy A,Robinot R,Vallet T,Nilsson-Payant BE,Hernandez-Armenta C,Dunham A,Weigang S,Knerr J,Modak M,Quintero D,Zhou Y,Dugourd A,Valdeolivas A,Patil T,Li Q,Hüttenhain R,Cakir M,Muralidharan M,Kim M,Jang G,Tutuncuoglu B,Hiatt J,Guo JZ,Xu J,Bouhaddou S,Mathy CJP,Gaulton A,Manners EJ,Félix E,Shi Y,Goff M,Lim JK,McBride T,O'Neal MC,Cai Y,Chang JCJ,Broadhurst DJ,Klippsten S,De Wit E,Leach AR,Kortemme T,Shoichet B,Ott M,Saez-Rodriguez J,tenOever BR,Mullins RD,Fischer ER,Kochs G,Grosse R,García-Sastre A,Vignuzzi M,Johnson JR,Shokat KM,Swaney DL,Beltrao P,Krogan NJ
200-01A was used in Enzyme-linked immunosorbent assay to present a quantitative mass spectrometry-based phosphoproteomics survey of SARS-CoV-2 infection in Vero E6 cells, revealing dramatic rewiring of phosphorylation on host and viral proteins.
Thu Aug 06 00:00:00 EDT 2020
The Global Phosphorylation Landscape of SARS-CoV-2 Infection.
Cell
Bouhaddou M,Memon D,Meyer B,White KM,Rezelj VV,Correa Marrero M,Polacco BJ,Melnyk JE,Ulferts S,Kaake RM,Batra J,Richards AL,Stevenson E,Gordon DE,Rojc A,Obernier K,Fabius JM,Soucheray M,Miorin L,Moreno E,Koh C,Tran QD,Hardy A,Robinot R,Vallet T,Nilsson-Payant BE,Hernandez-Armenta C,Dunham A,Weigang S,Knerr J,Modak M,Quintero D,Zhou Y,Dugourd A,Valdeolivas A,Patil T,Li Q,Hüttenhain R,Cakir M,Muralidharan M,Kim M,Jang G,Tutuncuoglu B,Hiatt J,Guo JZ,Xu J,Bouhaddou S,Mathy CJP,Gaulton A,Manners EJ,Félix E,Shi Y,Goff M,Lim JK,McBride T,O'Neal MC,Cai Y,Chang JCJ,Broadhurst DJ,Klippsten S,De Wit E,Leach AR,Kortemme T,Shoichet B,Ott M,Saez-Rodriguez J,tenOever BR,Mullins RD,Fischer ER,Kochs G,Grosse R,García-Sastre A,Vignuzzi M,Johnson JR,Shokat KM,Swaney DL,Beltrao P,Krogan NJ
200-01A was used in Enzyme-linked immunosorbent assay to present a quantitative mass spectrometry-based phosphoproteomics survey of SARS-CoV-2 infection in Vero E6 cells, revealing dramatic rewiring of phosphorylation on host and viral proteins.
Thu Aug 06 00:00:00 EDT 2020
Systematic analysis of the IL-17 receptor signalosome reveals a robust regulatory feedback loop.
The EMBO journal
Draberova H,Janusova S,Knizkova D,Semberova T,Pribikova M,Ujevic A,Harant K,Knapkova S,Hrdinka M,Fanfani V,Stracquadanio G,Drobek A,Ruppova K,Stepanek O,Draber P
Tue Sep 01 00:00:00 EDT 2020
3D micro-organisation printing of mammalian cells to generate biological tissues.
Scientific reports
Jeffries GDM,Xu S,Lobovkina T,Kirejev V,Tusseau F,Gyllensten C,Singh AK,Karila P,Moll L,Orwar O
Tue Nov 10 00:00:00 EST 2020
Synergism of TNF-α and IFN-γ triggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes.
bioRxiv : the preprint server for biology
Karki R,Sharma BR,Tuladhar S,Williams EP,Zalduondo L,Samir P,Zheng M,Sundaram B,Banoth B,Malireddi RKS,Schreiner P,Neale G,Vogel P,Webby R,Jonsson CB,Kanneganti TD
200-01A was used in In vitro experiments to reveal that blocking the COVID-19 cytokine-mediated inflammatory cell death signaling pathway identified in this study may benefit patients with COVID-19 or other cytokine storm-driven syndromes by limiting inflammation and tissue damage.
Fri Nov 13 00:00:00 EST 2020
The Coagulation and Immune Systems Are Directly Linked through the Activation of Interleukin-1α by Thrombin.
Immunity
Burzynski LC,Humphry M,Pyrillou K,Wiggins KA,Chan JNE,Figg N,Kitt LL,Summers C,Tatham KC,Martin PB,Bennett MR,Clarke MCH
Tue Apr 16 00:00:00 EDT 2019
PTEN-induced partial epithelial-mesenchymal transition drives diabetic kidney disease.
The Journal of clinical investigation
Li Y,Hu Q,Li C,Liang K,Xiang Y,Hsiao H,Nguyen TK,Park PK,Egranov SD,Ambati CR,Putluri N,Hawke DH,Han L,Hung MC,Danesh FR,Yang L,Lin C
Fri Mar 01 00:00:00 EST 2019
IL-1α cleavage by inflammatory caspases of the noncanonical inflammasome controls the senescence-associated secretory phenotype.
Aging cell
Wiggins KA,Parry AJ,Cassidy LD,Humphry M,Webster SJ,Goodall JC,Narita M,Clarke MCH
Sat Jun 01 00:00:00 EDT 2019
IL-1α cleavage by inflammatory caspases of the noncanonical inflammasome controls the senescence-associated secretory phenotype.
Aging cell
Wiggins KA,Parry AJ,Cassidy LD,Humphry M,Webster SJ,Goodall JC,Narita M,Clarke MCH
Sat Jun 01 00:00:00 EDT 2019
Activity of two hyaluronan preparations on primary human oral fibroblasts.
Journal of periodontal research
Asparuhova MB,Kiryak D,Eliezer M,Mihov D,Sculean A
Fri Feb 01 00:00:00 EST 2019
IL-36 promotes anti-viral immunity by boosting sensitivity to IFN-α/β in IRF1 dependent and independent manners.
Nature communications
Wang P,Gamero AM,Jensen LE
Wed Oct 16 00:00:00 EDT 2019
The differential statin effect on cytokine production of monocytes or macrophages is mediated by differential geranylgeranylation-dependent Rac1 activation.
Cell death & disease
Fu H,Alabdullah M,Großmann J,Spieler F,Abdosh R,Lutz V,Kalies K,Knöpp K,Rieckmann M,Koch S,Noutsias M,Pilowski C,Dutzmann J,Sedding D,Hüttelmaier S,Umezawa K,Werdan K,Loppnow H
Thu Nov 21 00:00:00 EST 2019
Therapeutically targeting tumor microenvironment-mediated drug resistance in estrogen receptor-positive breast cancer.
The Journal of experimental medicine
Shee K,Yang W,Hinds JW,Hampsch RA,Varn FS,Traphagen NA,Patel K,Cheng C,Jenkins NP,Kettenbach AN,Demidenko E,Owens P,Faber AC,Golub TR,Straussman R,Miller TW
Mon Mar 05 00:00:00 EST 2018
Inflammatory but not mitogenic contexts prime synovial fibroblasts for compensatory signaling responses to p38 inhibition.
Science signaling
Jones DS,Jenney AP,Joughin BA,Sorger PK,Lauffenburger DA
200-01A was used in In vitro experiments to investigate signaling pathways in rheumatoid arthritis.
Tue Mar 06 00:00:00 EST 2018
Recombinant Adenovirus KGHV500 and CIK Cells Codeliver Anti-p21-Ras scFv for the Treatment of Gastric Cancer with Wild-Type Ras Overexpression.
Molecular therapy oncolytics
Wang M,Hong Y,Feng Q,Pan X,Song S,Cui J,Lei J,Fang H,Yang J
200-01A was used in Cell Culture to study the antitumor effects of the recombinant oncolytic adenovirus carried by cytokine-induced killer (CIK) cells on n human gastric SGC7901 cells that overexpress wild-type Ras.
Fri Dec 21 00:00:00 EST 2018
Cytokine-induced killer cells as a feasible adoptive immunotherapy for the treatment of lung cancer.
Cell death & disease
Chen D,Sha H,Hu T,Dong S,Zhang J,Liu S,Cao H,Ma R,Wu Y,Jing C,Wang Z,Wu J,Feng J
Tue Mar 06 00:00:00 EST 2018
C10orf99 contributes to the development of psoriasis by promoting the proliferation of keratinocytes.
Scientific reports
Chen C,Wu N,Duan Q,Yang H,Wang X,Yang P,Zhang M,Liu J,Liu Z,Shao Y,Zheng Y
Tue Jun 05 00:00:00 EDT 2018
Structural basis for IL-1α recognition by a modified DNA aptamer that specifically inhibits IL-1α signaling.
Nature communications
Ren X,Gelinas AD,von Carlowitz I,Janjic N,Pyle AM
Mon Oct 09 00:00:00 EDT 2017
MUC2 Mucin and Butyrate Contribute to the Synthesis of the Antimicrobial Peptide Cathelicidin in Response to Entamoeba histolytica- and Dextran Sodium Sulfate-Induced Colitis.
Infection and immunity
Cobo ER,Kissoon-Singh V,Moreau F,Holani R,Chadee K
200-01A was used in Tissue/organ culture to demonstrate regulatory mechanisms between MUC2 and cathelicidins in the colonic mucosa where an intact mucus barrier is essential for expression and secretion of cathelicidins in response to E. histolytica- and DSS-induced colitis.
Wed Mar 01 00:00:00 EST 2017
Ablation of Perlecan Domain 1 Heparan Sulfate Reduces Progressive Cartilage Degradation, Synovitis, and Osteophyte Size in a Preclinical Model of Posttraumatic Osteoarthritis.
Arthritis & rheumatology (Hoboken, N.J.)
Shu CC,Jackson MT,Smith MM,Smith SM,Penm S,Lord MS,Whitelock JM,Little CB,Melrose J
Fri Apr 01 00:00:00 EDT 2016
Control of the Physical and Antimicrobial Skin Barrier by an IL-31-IL-1 Signaling Network.
Journal of immunology (Baltimore, Md. : 1950)
Hänel KH,Pfaff CM,Cornelissen C,Amann PM,Marquardt Y,Czaja K,Kim A,Lüscher B,Baron JM
Fri Apr 15 00:00:00 EDT 2016
Circular RNA Related to the Chondrocyte ECM Regulates MMP13 Expression by Functioning as a MiR-136 'Sponge' in Human Cartilage Degradation.
Scientific reports
Liu Q,Zhang X,Hu X,Dai L,Fu X,Zhang J,Ao Y
Wed Mar 02 00:00:00 EST 2016
A Disintegrin and Metalloproteinase with Thrombospondin Motifs-5 (ADAMTS-5) Forms Catalytically Active Oligomers.
The Journal of biological chemistry
Kosasih HJ,Last K,Rogerson FM,Golub SB,Gauci SJ,Russo VC,Stanton H,Wilson R,Lamande SR,Holden P,Fosang AJ
Fri Feb 12 00:00:00 EST 2016
Inhibition of interleukin-1 signaling enhances elimination of tyrosine kinase inhibitor-treated CML stem cells.
Blood
Zhang B,Chu S,Agarwal P,Campbell VL,Hopcroft L,Jørgensen HG,Lin A,Gaal K,Holyoake TL,Bhatia R
200-01A was used in Cell Culture to show here that CML LSC demonstrated increased expression of the IL-1 receptors, IL-1 receptor accessory protein and IL-1 receptor type 1 (IL-1R1), and enhanced sensitivity to IL-1-induced NF-κB signaling compared with normal stem cells.
Thu Dec 08 00:00:00 EST 2016
The Inhibitory Effects of Anti-Oxidants on Ultraviolet-Induced Up-Regulation of the Wrinkling-Inducing Enzyme Neutral Endopeptidase in Human Fibroblasts.
PloS one
Nakajima H,Terazawa S,Niwano T,Yamamoto Y,Imokawa G
200-01A was used in In vitro experiments to strongly support the in vivo anti-wrinkling effects of ubiquinol10 and AX on human and animal skin and provide convincing proof of the UV-induced wrinkling mechanism that essentially focuses on the over-expression of NEP by dermal fibroblasts as an intrinsic causative factor.
Fri Aug 11 00:00:00 EDT 2017
Novel Noncompetitive IL-1 Receptor-Biased Ligand Prevents Infection- and Inflammation-Induced Preterm Birth.
Journal of immunology (Baltimore, Md. : 1950)
Nadeau-Vallée M,Quiniou C,Palacios J,Hou X,Erfani A,Madaan A,Sanchez M,Leimert K,Boudreault A,Duhamel F,Rivera JC,Zhu T,Noueihed B,Robertson SA,Ni X,Olson DM,Lubell W,Girard S,Chemtob S
Thu Oct 01 00:00:00 EDT 2015
Network-Based Analysis of Nutraceuticals in Human Hepatocellular Carcinomas Reveals Mechanisms of Chemopreventive Action.
CPT: pharmacometrics & systems pharmacology
Michailidou M,Melas IN,Messinis DE,Klamt S,Alexopoulos LG,Kolisis FN,Loutrari H
Mon Jun 01 00:00:00 EDT 2015
Galectin-1 regulates tissue exit of specific dendritic cell populations.
The Journal of biological chemistry
Thiemann S,Man JH,Chang MH,Lee B,Baum LG
Fri Sep 11 00:00:00 EDT 2015
Peptides genetically selected for NF-κB activation cooperate with oncogene Ras and model carcinogenic role of inflammation.
Proceedings of the National Academy of Sciences of the United States of America
Natarajan V,Komarov AP,Ippolito T,Bonneau K,Chenchik AA,Gudkov AV
Tue Jan 28 00:00:00 EST 2014
HSCARG downregulates NF-κB signaling by interacting with USP7 and inhibiting NEMO ubiquitination.
Cell death & disease
Li T,Guan J,Li S,Zhang X,Zheng X
Thu May 15 00:00:00 EDT 2014
Cytokine systems approach demonstrates differences in innate and pro-inflammatory host responses between genetically distinct MERS-CoV isolates.
BMC genomics
Selinger C,Tisoncik-Go J,Menachery VD,Agnihothram S,Law GL,Chang J,Kelly SM,Sova P,Baric RS,Katze MG
200-01A was used in Cell Culture to carry out comparative transcriptional analysis of human Calu-3 cell host responses to the different coronavirus in the Middle East (MERS-CoV) strains.
Mon Dec 22 00:00:00 EST 2014
Poxvirus targeting of E3 ligase β-TrCP by molecular mimicry: a mechanism to inhibit NF-κB activation and promote immune evasion and virulence.
PLoS pathogens
Mansur DS,Maluquer de Motes C,Unterholzner L,Sumner RP,Ferguson BJ,Ren H,Strnadova P,Bowie AG,Smith GL
Fri Feb 01 00:00:00 EST 2013
High doses of romiplostim induce proliferation and reduce proplatelet formation by human megakaryocytes.
PloS one
Currao M,Balduini CL,Balduini A
Fri Sep 06 00:00:00 EDT 2013
Loss of TAK1 increases cell traction force in a ROS-dependent manner to drive epithelial-mesenchymal transition of cancer cells.
Cell death & disease
Lam CR,Tan C,Teo Z,Tay CY,Phua T,Wu YL,Cai PQ,Tan LP,Chen X,Zhu P,Tan NS
Thu Oct 10 00:00:00 EDT 2013
Paracrine cytokine mechanisms underlying the hyperpigmentation of seborrheic keratosis in covered skin areas.
The Journal of dermatology
Takenaka Y,Hoshino Y,Nakajima H,Hayashi N,Kawashima M,Imokawa G
200-01A was used in In vitro experiments to establish SK cell lines to examine whether SK basaloid cells are less sensitive to SCF-inducible stimulation than are normal human keratinocytes (NHK).
Mon Jul 01 00:00:00 EDT 2013
Positive feedback regulation of human inducible nitric-oxide synthase expression by Ras protein S-nitrosylation.
The Journal of biological chemistry
Lee M,Choy JC
Fri May 31 00:00:00 EDT 2013
Mast cells play a protumorigenic role in primary cutaneous lymphoma.
Blood
Rabenhorst A,Schlaak M,Heukamp LC,Förster A,Theurich S,von Bergwelt-Baildon M,Büttner R,Kurschat P,Mauch C,Roers A,Hartmann K
Thu Sep 06 00:00:00 EDT 2012
Multiple receptors trigger human NK cell-mediated cytotoxicity against porcine chondrocytes.
Journal of immunology (Baltimore, Md. : 1950)
Sommaggio R,Cohnen A,Watzl C,Costa C
Thu Mar 01 00:00:00 EST 2012
Comprehensive analysis of tumor microenvironment cytokines in Waldenstrom macroglobulinemia identifies CCL5 as a novel modulator of IL-6 activity.
Blood
Elsawa SF,Novak AJ,Ziesmer SC,Almada LL,Hodge LS,Grote DM,Witzig TE,Fernandez-Zapico ME,Ansell SM
Thu Nov 17 00:00:00 EST 2011
Anti-inflammatory activity of monogalactosyldiacylglycerol in human articular cartilage in vitro: activation of an anti-inflammatory cyclooxygenase-2 (COX-2) pathway.
Arthritis research & therapy
Ulivi V,Lenti M,Gentili C,Marcolongo G,Cancedda R,Descalzi Cancedda F
Fri Jun 17 00:00:00 EDT 2011
Gemcitabine/cannabinoid combination triggers autophagy in pancreatic cancer cells through a ROS-mediated mechanism.
Cell death & disease
Donadelli M,Dando I,Zaniboni T,Costanzo C,Dalla Pozza E,Scupoli MT,Scarpa A,Zappavigna S,Marra M,Abbruzzese A,Bifulco M,Caraglia M,Palmieri M
Thu Apr 28 00:00:00 EDT 2011
DNA damage-mediated induction of a chemoresistant niche.
Cell
Gilbert LA,Hemann MT
Fri Oct 29 00:00:00 EDT 2010
S100A8 and S100A9 in experimental osteoarthritis.
Arthritis research & therapy
Zreiqat H,Belluoccio D,Smith MM,Wilson R,Rowley LA,Jones K,Ramaswamy Y,Vogl T,Roth J,Bateman JF,Little CB
Fri Aug 13 00:00:00 EDT 2010
Critical regulation of early Th17 cell differentiation by interleukin-1 signaling.
Immunity
Chung Y,Chang SH,Martinez GJ,Yang XO,Nurieva R,Kang HS,Ma L,Watowich SS,Jetten AM,Tian Q,Dong C
Fri Apr 17 00:00:00 EDT 2009
C7 is expressed on endothelial cells as a trap for the assembling terminal complement complex and may exert anti-inflammatory function.
Blood
Bossi F,Rizzi L,Bulla R,Debeus A,Tripodo C,Picotti P,Betto E,Macor P,Pucillo C,Würzner R,Tedesco F
Thu Apr 09 00:00:00 EDT 2009
Regulation of epithelial-mesenchymal IL-1 signaling by PPARbeta/delta is essential for skin homeostasis and wound healing.
The Journal of cell biology
Chong HC,Tan MJ,Philippe V,Tan SH,Tan CK,Ku CW,Goh YY,Wahli W,Michalik L,Tan NS
Mon Mar 23 00:00:00 EDT 2009
Microdialysis of cytokines: methodological considerations, scanning electron microscopy, and determination of relative recovery.
Journal of neurotrauma
Helmy A,Carpenter KL,Skepper JN,Kirkpatrick PJ,Pickard JD,Hutchinson PJ
Wed Apr 01 00:00:00 EDT 2009
NEMO-binding domains of both IKKalpha and IKKbeta regulate IkappaB kinase complex assembly and classical NF-kappaB activation.
The Journal of biological chemistry
Solt LA,Madge LA,May MJ
Fri Oct 02 00:00:00 EDT 2009
Interleukin (IL)-1 promotes allogeneic T cell intimal infiltration and IL-17 production in a model of human artery rejection.
The Journal of experimental medicine
Rao DA,Eid RE,Qin L,Yi T,Kirkiles-Smith NC,Tellides G,Pober JS
Mon Dec 22 00:00:00 EST 2008
Generation and regulation of human CD4+ IL-17-producing T cells in ovarian cancer.
Proceedings of the National Academy of Sciences of the United States of America
Miyahara Y,Odunsi K,Chen W,Peng G,Matsuzaki J,Wang RF
Tue Oct 07 00:00:00 EDT 2008
Development and validation of human psoriatic skin equivalents.
The American journal of pathology
Tjabringa G,Bergers M,van Rens D,de Boer R,Lamme E,Schalkwijk J
Mon Sep 01 00:00:00 EDT 2008
Genetically programmed differences in epidermal host defense between psoriasis and atopic dermatitis patients.
PloS one
Zeeuwen PL,de Jongh GJ,Rodijk-Olthuis D,Kamsteeg M,Verhoosel RM,van Rossum MM,Hiemstra PS,Schalkwijk J
Wed Jun 04 00:00:00 EDT 2008
The NF-kappaB regulator Bcl-3 and the BH3-only proteins Bim and Puma control the death of activated T cells.
Proceedings of the National Academy of Sciences of the United States of America
Bauer A,Villunger A,Labi V,Fischer SF,Strasser A,Wagner H,Schmid RM,Häcker G
Tue Jul 18 00:00:00 EDT 2006
Interleukin-1beta enhances GABAA receptor cell-surface expression by a phosphatidylinositol 3-kinase/Akt pathway: relevance to sepsis-associated encephalopathy.
The Journal of biological chemistry
Serantes R,Arnalich F,Figueroa M,Salinas M,Andrés-Mateos E,Codoceo R,Renart J,Matute C,Cavada C,Cuadrado A,Montiel C
Fri May 26 00:00:00 EDT 2006
Interleukin-1beta but not IL-1alpha binds to fibrinogen and fibrin and has enhanced activity in the bound form.
Blood
Sahni A,Guo M,Sahni SK,Francis CW
Thu Jul 15 00:00:00 EDT 2004
Modulation of coxsackie-adenovirus receptor expression for increased adenoviral transgene expression.
Cancer research
Hemminki A,Kanerva A,Liu B,Wang M,Alvarez RD,Siegal GP,Curiel DT
Sat Feb 15 00:00:00 EST 2003
