Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This peptide corresponds to 18 amino acids near the amino terminus of human KANK3.
PEP-1583 can be used as a blocking peptide with polyclonal antibody PA5-34540. For use as a blocking peptide in Western blot, incubate the peptide with equal volume of antibody for 30 min at 37ºC.
Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. Like other members of the KANK family, KANK3 (KN motif and ankyrin repeat domain-containing protein 3), is thought to play a role in the formation of actin stress fibers. In zebrafish, the homolog of KANK3 interacts with the adaptor protein Numb, a protein implicated in multiple basic cellular processes, and is essential for epidermal integrity and neurulation, suggesting that KANK3 may play a similar role in higher organisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ankyrin repeat domain 47; Ankyrin repeat domain-containing protein 47; kidney ankyrin repeat-containing protein 3; KN motif and ankyrin repeat domain-containing protein 3
Gene Aliases: ANKRD47; KANK3
UniProt ID: (Human) Q6NY19
Entrez Gene ID: (Human) 256949
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support