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This peptide corresponds to 15 amino acids near the carboxy terminus of human LNPEP.
PEP-1500 can be used as a blocking peptide with polyclonal antibody PA5-34458.
This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Protein Aliases: angiotensin IV receptor; AT (4) receptor; Cystinyl aminopeptidase; insulin-regulated aminopeptidase; Insulin-regulated membrane aminopeptidase; Insulin-responsive aminopeptidase; IRAP; Leucyl-cystinyl aminopeptidase; leucyl/cystinyl aminopeptidase; OTase; Oxytocinase; P-LAP; Placental leucine aminopeptidase; vasopressinase; vp160
Gene Aliases: CAP; IRAP; LNPEP; OTASE; P-LAP; PLAP
UniProt ID: (Human) Q9UIQ6
Entrez Gene ID: (Human) 4012
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