Product References
Sonic Hedgehog acts as a macrophage chemoattractant during regeneration of the gastric epithelium.
NPJ Regenerative medicine
Chakrabarti J,Dua-Awereh M,Schumacher M,Engevik A,Hawkins J,Helmrath MA,Zavros Y
AF-300-25 was used in In vitro experiments to investigate the extent of morphogenic sonic hedgehog in gastric epithelium regeneration.
Wed Jan 12 00:00:00 EST 2022
Danger signal extracellular calcium initiates differentiation of monocytes into SPP1/osteopontin-producing macrophages.
Cell death & disease
Murthy S,Karkossa I,Schmidt C,Hoffmann A,Hagemann T,Rothe K,Seifert O,Anderegg U,von Bergen M,Schubert K,Rossol M
Wed Jan 12 00:00:00 EST 2022
USP19 (ubiquitin specific peptidase 19) promotes TBK1 (TANK-binding kinase 1) degradation via chaperone-mediated autophagy.
Autophagy
Zhao X,Di Q,Yu J,Quan J,Xiao Y,Zhu H,Li H,Ling J,Chen W
AF-300-25 was used in Cell Culture to suggest that USP19 is a key regulator of TBK1 and uncovers a previously uncharacterized role for USP19 in CMA-mediated TBK1 degradation and infectious diseases.
Fri Apr 01 00:00:00 EDT 2022
Wear of hip prostheses increases serum IGFBP-1 levels in patients with aseptic loosening.
Scientific reports
Vallés G,García-Rey E,Saldaña L,García-Cimbrelo E,Vilaboa N
Tue Jan 12 00:00:00 EST 2021
Human physiomimetic model integrating microphysiological systems of the gut, liver, and brain for studies of neurodegenerative diseases.
Science advances
Trapecar M,Wogram E,Svoboda D,Communal C,Omer A,Lungjangwa T,Sphabmixay P,Velazquez J,Schneider K,Wright CW,Mildrum S,Hendricks A,Levine S,Muffat J,Lee MJ,Lauffenburger DA,Trumper D,Jaenisch R,Griffith LG
AF-300-25 was used in In vitro experiments to develop a mesofluidic platform technology to study gut-liver-cerebral interactions in the context of Parkinson's disease (PD).
Fri Jan 01 00:00:00 EST 2021
Macrophages rely on extracellular serine to suppress aberrant cytokine production.
Scientific reports
Kurita K,Ohta H,Shirakawa I,Tanaka M,Kitaura Y,Iwasaki Y,Matsuzaka T,Shimano H,Aoe S,Arima H,Ogawa Y,Ito A,Suganami T
Thu May 27 00:00:00 EDT 2021
Breast tumor stiffness instructs bone metastasis via maintenance of mechanical conditioning.
Cell reports
Watson AW,Grant AD,Parker SS,Hill S,Whalen MB,Chakrabarti J,Harman MW,Roman MR,Forte BL,Gowan CC,Castro-Portuguez R,Stolze LK,Franck C,Cusanovich DA,Zavros Y,Padi M,Romanoski CE,Mouneimne G
Tue Jun 29 00:00:00 EDT 2021
A human CD137×PD-L1 bispecific antibody promotes anti-tumor immunity via context-dependent T cell costimulation and checkpoint blockade.
Nature communications
Geuijen C,Tacken P,Wang LC,Klooster R,van Loo PF,Zhou J,Mondal A,Liu YB,Kramer A,Condamine T,Volgina A,Hendriks LJA,van der Maaden H,Rovers E,Engels S,Fransen F,den Blanken-Smit R,Zondag-van der Zande V,Basmeleh A,Bartelink W,Kulkarni A,Marissen W,Huang CY,Hall L,Harvey S,Kim S,Martinez M,O'Brien S,Moon E,Albelda S,Kanellopoulou C,Stewart S,Nastri H,Bakker ABH,Scherle P,Logtenberg T,Hollis G,de Kruif J,Huber R,Mayes PA,Throsby M
Wed Jul 21 00:00:00 EDT 2021
The transition of M-CSF-derived human macrophages to a growth-promoting phenotype.
Blood advances
Hamidzadeh K,Belew AT,El-Sayed NM,Mosser DM
AF-300-25 was used in Sample Preparation (ELISA) to demonstrate that inflammation induced by Toll-like receptor stimulation is followed by the upregulation of receptors for adenosine and prostaglandin E2, which help terminate macrophage activation and initiate tissue remodeling and angiogenesis.
Tue Nov 10 00:00:00 EST 2020
Higher Order Architecture of Designer Peptides Forms Bioinspired 10 nm siRNA Delivery System.
Scientific reports
Gamboa A,Urfano SF,Hernandez K,Fraser DA,Ayalew L,Slowinska K
Thu Nov 14 00:00:00 EST 2019
The differential statin effect on cytokine production of monocytes or macrophages is mediated by differential geranylgeranylation-dependent Rac1 activation.
Cell death & disease
Fu H,Alabdullah M,Großmann J,Spieler F,Abdosh R,Lutz V,Kalies K,Knöpp K,Rieckmann M,Koch S,Noutsias M,Pilowski C,Dutzmann J,Sedding D,Hüttelmaier S,Umezawa K,Werdan K,Loppnow H
Thu Nov 21 00:00:00 EST 2019
Salt-inducible kinase 1 regulates bone anabolism via the CRTC1-CREB-Id1 axis.
Cell death & disease
Kim MK,Kwon JO,Song MK,Kim B,Kim H,Lee ZH,Koo SH,Kim HH
Thu Oct 31 00:00:00 EDT 2019
Acute Iron Deprivation Reprograms Human Macrophage Metabolism and Reduces Inflammation In Vivo.
Cell reports
Pereira M,Chen TD,Buang N,Olona A,Ko JH,Prendecki M,Costa ASH,Nikitopoulou E,Tronci L,Pusey CD,Cook HT,McAdoo SP,Frezza C,Behmoaras J
AF-300-25 was used in Cell Culture to suggest that acute iron deprivation has in vivo protective effects mediated by an anti-inflammatory immunometabolic switch in macrophages.
Tue Jul 09 00:00:00 EDT 2019
Short exposure to cold atmospheric plasma induces senescence in human skin fibroblasts and adipose mesenchymal stromal cells.
Scientific reports
Bourdens M,Jeanson Y,Taurand M,Juin N,Carrière A,Clément F,Casteilla L,Bulteau AL,Planat-Bénard V
Mon Jun 17 00:00:00 EDT 2019
IFN-γ selectively suppresses a subset of TLR4-activated genes and enhancers to potentiate macrophage activation.
Nature communications
Kang K,Bachu M,Park SH,Kang K,Bae S,Park-Min KH,Ivashkiv LB
Thu Jul 25 00:00:00 EDT 2019
Hepatic caveolin-1 is enhanced in Cyp27a1/ApoE double knockout mice.
FEBS open bio
Zurkinden L,Mansour YT,Rohrbach B,Vogt B,Mistry HD,Escher G
Sat Oct 01 00:00:00 EDT 2016
High salt primes a specific activation state of macrophages, M(Na).
Cell research
Zhang WC,Zheng XJ,Du LJ,Sun JY,Shen ZX,Shi C,Sun S,Zhang Z,Chen XQ,Qin M,Liu X,Tao J,Jia L,Fan HY,Zhou B,Yu Y,Ying H,Hui L,Liu X,Yi X,Liu X,Zhang L,Duan SZ
Sat Aug 01 00:00:00 EDT 2015
Reversible ubiquitination shapes NLRC5 function and modulates NF-κB activation switch.
The Journal of cell biology
Meng Q,Cai C,Sun T,Wang Q,Xie W,Wang R,Cui J
Mon Dec 07 00:00:00 EST 2015
A Food and Drug Administration-approved asthma therapeutic agent impacts amyloid β in the brain in a transgenic model of Alzheimer disease.
The Journal of biological chemistry
Hori Y,Takeda S,Cho H,Wegmann S,Shoup TM,Takahashi K,Irimia D,Elmaleh DR,Hyman BT,Hudry E
Fri Jan 23 00:00:00 EST 2015
A novel antibody-drug conjugate targeting SAIL for the treatment of hematologic malignancies.
Blood cancer journal
Kim SY,Theunissen JW,Balibalos J,Liao-Chan S,Babcock MC,Wong T,Cairns B,Gonzalez D,van der Horst EH,Perez M,Levashova Z,Chinn L,D'Alessio JA,Flory M,Bermudez A,Jackson DY,Ha E,Monteon J,Bruhns MF,Chen G,Migone TS
Fri May 29 00:00:00 EDT 2015
Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences.
Blood
Martinez FO,Helming L,Milde R,Varin A,Melgert BN,Draijer C,Thomas B,Fabbri M,Crawshaw A,Ho LP,Ten Hacken NH,Cobos Jiménez V,Kootstra NA,Hamann J,Greaves DR,Locati M,Mantovani A,Gordon S
Thu Feb 28 00:00:00 EST 2013
Systemic circulation and bone recruitment of osteoclast precursors tracked by using fluorescent imaging techniques.
Journal of immunology (Baltimore, Md. : 1950)
Kotani M,Kikuta J,Klauschen F,Chino T,Kobayashi Y,Yasuda H,Tamai K,Miyawaki A,Kanagawa O,Tomura M,Ishii M
Tue Jan 15 00:00:00 EST 2013
An HLA-DRB1-coded signal transduction ligand facilitates inflammatory arthritis: a new mechanism of autoimmunity.
Journal of immunology (Baltimore, Md. : 1950)
Holoshitz J,Liu Y,Fu J,Joseph J,Ling S,Colletta A,Sharma P,Begun D,Goldstein S,Taichman R
Tue Jan 01 00:00:00 EST 2013
Hypertonic stress promotes autophagy and microtubule-dependent autophagosomal clusters.
Autophagy
Nunes P,Ernandez T,Roth I,Qiao X,Strebel D,Bouley R,Charollais A,Ramadori P,Foti M,Meda P,Féraille E,Brown D,Hasler U
AF-300-25 was used in Cell Culture to show that hypertonicity induces fast reorganization of microtubule networks, which is associated with strong reorganization of microtubules at centrosomes and fragmentation of Golgi ribbons.
Mon Apr 01 00:00:00 EDT 2013
Microfluidic chemotaxis platform for differentiating the roles of soluble and bound amyloid-β on microglial accumulation.
Scientific reports
Cho H,Hashimoto T,Wong E,Hori Y,Wood LB,Zhao L,Haigis KM,Hyman BT,Irimia D
AF-300-25 was used in Cell Culture to investigate microglial accumulation of Aβ.
Mon Jun 23 00:00:00 EDT 2014
A FOXO3-IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses.
Nature
Litvak V,Ratushny AV,Lampano AE,Schmitz F,Huang AC,Raman A,Rust AG,Bergthaler A,Aitchison JD,Aderem A
Thu Oct 18 00:00:00 EDT 2012
The rs1143679 (R77H) lupus associated variant of ITGAM (CD11b) impairs complement receptor 3 mediated functions in human monocytes.
Annals of the rheumatic diseases
Rhodes B,Fürnrohr BG,Roberts AL,Tzircotis G,Schett G,Spector TD,Vyse TJ
Sat Dec 01 00:00:00 EST 2012
Role of c-MYC in alternative activation of human macrophages and tumor-associated macrophage biology.
Blood
Pello OM,De Pizzol M,Mirolo M,Soucek L,Zammataro L,Amabile A,Doni A,Nebuloni M,Swigart LB,Evan GI,Mantovani A,Locati M
Thu Jan 12 00:00:00 EST 2012
Bruton tyrosine kinase inhibition is a novel therapeutic strategy targeting tumor in the bone marrow microenvironment in multiple myeloma.
Blood
Tai YT,Chang BY,Kong SY,Fulciniti M,Yang G,Calle Y,Hu Y,Lin J,Zhao JJ,Cagnetta A,Cea M,Sellitto MA,Zhong MY,Wang Q,Acharya C,Carrasco DR,Buggy JJ,Elias L,Treon SP,Matsui W,Richardson P,Munshi NC,Anderson KC
Thu Aug 30 00:00:00 EDT 2012
C/EBPε mediates nicotinamide-enhanced clearance of Staphylococcus aureus in mice.
The Journal of clinical investigation
Kyme P,Thoennissen NH,Tseng CW,Thoennissen GB,Wolf AJ,Shimada K,Krug UO,Lee K,Müller-Tidow C,Berdel WE,Hardy WD,Gombart AF,Koeffler HP,Liu GY
Sat Sep 01 00:00:00 EDT 2012
Pre-B cell to macrophage transdifferentiation without significant promoter DNA methylation changes.
Nucleic acids research
Rodríguez-Ubreva J,Ciudad L,Gómez-Cabrero D,Parra M,Bussmann LH,di Tullio A,Kallin EM,Tegnér J,Graf T,Ballestar E
Thu Mar 01 00:00:00 EST 2012
Identification of Axl as a downstream effector of TGF-β1 during Langerhans cell differentiation and epidermal homeostasis.
The Journal of experimental medicine
Bauer T,Zagórska A,Jurkin J,Yasmin N,Köffel R,Richter S,Gesslbauer B,Lemke G,Strobl H
Mon Oct 22 00:00:00 EDT 2012
TNF-induced osteoclastogenesis and inflammatory bone resorption are inhibited by transcription factor RBP-J.
The Journal of experimental medicine
Zhao B,Grimes SN,Li S,Hu X,Ivashkiv LB
Mon Feb 13 00:00:00 EST 2012
A novel method for autophagy detection in primary cells: impaired levels of macroautophagy in immunosenescent T cells.
Autophagy
Phadwal K,Alegre-Abarrategui J,Watson AS,Pike L,Anbalagan S,Hammond EM,Wade-Martins R,McMichael A,Klenerman P,Simon AK
Sun Apr 01 00:00:00 EDT 2012
IL-10-induced microRNA-187 negatively regulates TNF-α, IL-6, and IL-12p40 production in TLR4-stimulated monocytes.
Proceedings of the National Academy of Sciences of the United States of America
Rossato M,Curtale G,Tamassia N,Castellucci M,Mori L,Gasperini S,Mariotti B,De Luca M,Mirolo M,Cassatella MA,Locati M,Bazzoni F
Tue Nov 06 00:00:00 EST 2012
Direct and immune mediated antibody targeting of ERBB receptors in a colorectal cancer cell-line panel.
Proceedings of the National Academy of Sciences of the United States of America
Ashraf SQ,Nicholls AM,Wilding JL,Ntouroupi TG,Mortensen NJ,Bodmer WF
Tue Dec 18 00:00:00 EST 2012
Spleen serves as a reservoir of osteoclast precursors through vitamin D-induced IL-34 expression in osteopetrotic op/op mice.
Proceedings of the National Academy of Sciences of the United States of America
Nakamichi Y,Mizoguchi T,Arai A,Kobayashi Y,Sato M,Penninger JM,Yasuda H,Kato S,DeLuca HF,Suda T,Udagawa N,Takahashi N
Tue Jun 19 00:00:00 EDT 2012
Paracrine interactions between primary human macrophages and human fibroblasts enhance murine mammary gland humanization in vivo.
Breast cancer research : BCR
Fleming JM,Miller TC,Kidacki M,Ginsburg E,Stuelten CH,Stewart DA,Troester MA,Vonderhaar BK
Mon Jun 25 00:00:00 EDT 2012
Interleukin-34 produced by human fibroblast-like synovial cells in rheumatoid arthritis supports osteoclastogenesis.
Arthritis research & therapy
Hwang SJ,Choi B,Kang SS,Chang JH,Kim YG,Chung YH,Sohn DH,So MW,Lee CK,Robinson WH,Chang EJ
Fri Jan 20 00:00:00 EST 2012
Purinergic receptors are required for HIV-1 infection of primary human macrophages.
Journal of immunology (Baltimore, Md. : 1950)
Hazleton JE,Berman JW,Eugenin EA
Tue May 01 00:00:00 EDT 2012
NLRC4 inflammasome-mediated production of IL-1β modulates mucosal immunity in the lung against gram-negative bacterial infection.
Journal of immunology (Baltimore, Md. : 1950)
Cai S,Batra S,Wakamatsu N,Pacher P,Jeyaseelan S
Fri Jun 01 00:00:00 EDT 2012
Production of TNF-α in macrophages activated by T cells, compared with lipopolysaccharide, uses distinct IL-10-dependent regulatory mechanism.
Journal of immunology (Baltimore, Md. : 1950)
Agbanoma G,Li C,Ennis D,Palfreeman AC,Williams LM,Brennan FM
Wed Feb 01 00:00:00 EST 2012
Complement protein C1q directs macrophage polarization and limits inflammasome activity during the uptake of apoptotic cells.
Journal of immunology (Baltimore, Md. : 1950)
Benoit ME,Clarke EV,Morgado P,Fraser DA,Tenner AJ
Fri Jun 01 00:00:00 EDT 2012
Efficient clearance of early apoptotic cells by human macrophages requires M2c polarization and MerTK induction.
Journal of immunology (Baltimore, Md. : 1950)
Zizzo G,Hilliard BA,Monestier M,Cohen PL
Mon Oct 01 00:00:00 EDT 2012
Diesel exhaust particle exposure in vitro alters monocyte differentiation and function.
PloS one
Chaudhuri N,Jary H,Lea S,Khan N,Piddock KC,Dockrell DH,Donaldson K,Duffin R,Singh D,Parker LC,Sabroe I
Fri May 24 00:00:00 EDT 2013
TLT-1s, alternative transcripts of triggering receptor expressed on myeloid cell-like transcript-1 (TLT-1), Inhibits the triggering receptor expressed on myeloid cell-2 (TREM-2)-mediated signaling pathway during osteoclastogenesis.
The Journal of biological chemistry
Yoon SH,Lee YD,Ha J,Lee Y,Kim HH
Fri Aug 24 00:00:00 EDT 2012
Adipokines in psoriatic arthritis patients: the correlations with osteoclast precursors and bone erosions.
PloS one
Xue Y,Jiang L,Cheng Q,Chen H,Yu Y,Lin Y,Yang X,Kong N,Zhu X,Xu X,Wan W,Zou H
Tue Aug 26 00:00:00 EDT 2014
Promotion of human early embryonic development and blastocyst outgrowth in vitro using autocrine/paracrine growth factors.
PloS one
Kawamura K,Chen Y,Shu Y,Cheng Y,Qiao J,Behr B,Pera RA,Hsueh AJ
Tue May 07 00:00:00 EDT 2013
Tailored enrichment strategy detects low abundant small noncoding RNAs in HIV-1 infected cells.
Retrovirology
Althaus CF,Vongrad V,Niederöst B,Joos B,Di Giallonardo F,Rieder P,Pavlovic J,Trkola A,Günthard HF,Metzner KJ,Fischer M
Thu Mar 29 00:00:00 EDT 2012
Characterization and function of the human macrophage dopaminergic system: implications for CNS disease and drug abuse.
Journal of neuroinflammation
Gaskill PJ,Carvallo L,Eugenin EA,Berman JW
Sat Aug 18 00:00:00 EDT 2012
Characterization of a mutated IgA2 antibody of the m(1) allotype against the epidermal growth factor receptor for the recruitment of monocytes and macrophages.
The Journal of biological chemistry
Lohse S,Brunke C,Derer S,Peipp M,Boross P,Kellner C,Beyer T,Dechant M,van der Winkel JG,Leusen JH,Valerius T
Fri Jul 20 00:00:00 EDT 2012
MiniCD4 protein resistance mutations affect binding to the HIV-1 gp120 CD4 binding site and decrease entry efficiency.
Retrovirology
Grupping K,Selhorst P,Michiels J,Vereecken K,Heyndrickx L,Kessler P,Vanham G,Martin L,Ariën KK
Wed May 02 00:00:00 EDT 2012
The chemerin/ChemR23 system does not affect the pro-inflammatory response of mouse and human macrophages ex vivo.
PloS one
Bondue B,De Henau O,Luangsay S,Devosse T,de Nadaï P,Springael JY,Parmentier M,Vosters O
Tue Nov 27 00:00:00 EST 2012
Rho GTPase expression in human myeloid cells.
PloS one
van Helden SF,Anthony EC,Dee R,Hordijk PL
Wed May 15 00:00:00 EDT 2013
Monocytes contribute to differential immune pressure on R5 versus X4 HIV through the adipocytokine visfatin/NAMPT.
PloS one
Van den Bergh R,Morin S,Sass HJ,Grzesiek S,Vekemans M,Florence E,Tran HT,Imiru RG,Heyndrickx L,Vanham G,De Baetselier P,Raes G
Tue Sep 04 00:00:00 EDT 2012
Dasatinib as a bone-modifying agent: anabolic and anti-resorptive effects.
PloS one
Garcia-Gomez A,Ocio EM,Crusoe E,Santamaria C,Hernández-Campo P,Blanco JF,Sanchez-Guijo FM,Hernández-Iglesias T,Briñón JG,Fisac-Herrero RM,Lee FY,Pandiella A,San Miguel JF,Garayoa M
Mon Sep 10 00:00:00 EDT 2012
Innate and adaptive interferons suppress IL-1α and IL-1β production by distinct pulmonary myeloid subsets during Mycobacterium tuberculosis infection.
Immunity
Mayer-Barber KD,Andrade BB,Barber DL,Hieny S,Feng CG,Caspar P,Oland S,Gordon S,Sher A
Fri Dec 23 00:00:00 EST 2011
Fc gamma receptor IIb on target B cells promotes rituximab internalization and reduces clinical efficacy.
Blood
Lim SH,Vaughan AT,Ashton-Key M,Williams EL,Dixon SV,Chan HT,Beers SA,French RR,Cox KL,Davies AJ,Potter KN,Mockridge CI,Oscier DG,Johnson PW,Cragg MS,Glennie MJ
Thu Sep 01 00:00:00 EDT 2011
Plasma carboxypeptidase B downregulates inflammatory responses in autoimmune arthritis.
The Journal of clinical investigation
Song JJ,Hwang I,Cho KH,Garcia MA,Kim AJ,Wang TH,Lindstrom TM,Lee AT,Nishimura T,Zhao L,Morser J,Nesheim M,Goodman SB,Lee DM,Bridges SL,Gregersen PK,Leung LL,Robinson WH
Thu Sep 01 00:00:00 EDT 2011
Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection.
The Journal of experimental medicine
Séror C,Melki MT,Subra F,Raza SQ,Bras M,Saïdi H,Nardacci R,Voisin L,Paoletti A,Law F,Martins I,Amendola A,Abdul-Sater AA,Ciccosanti F,Delelis O,Niedergang F,Thierry S,Said-Sadier N,Lamaze C,Métivier D,Estaquier J,Fimia GM,Falasca L,Casetti R,Modjtahedi N,Kanellopoulos J,Mouscadet JF,Ojcius DM,Piacentini M,Gougeon ML,Kroemer G,Perfettini JL
Mon Aug 29 00:00:00 EDT 2011
Resistance to regulatory T cell-mediated suppression in rheumatoid arthritis can be bypassed by ectopic foxp3 expression in pathogenic synovial T cells.
Proceedings of the National Academy of Sciences of the United States of America
Beavis PA,Gregory B,Green P,Cribbs AP,Kennedy A,Amjadi P,Palfreeman AC,Feldmann M,Brennan FM
Tue Oct 04 00:00:00 EDT 2011
MMP-13 stimulates osteoclast differentiation and activation in tumour breast bone metastases.
Breast cancer research : BCR
Pivetta E,Scapolan M,Pecolo M,Wassermann B,Abu-Rumeileh I,Balestreri L,Borsatti E,Tripodo C,Colombatti A,Spessotto P
Thu Oct 27 00:00:00 EDT 2011
Hck tyrosine kinase regulates TLR4-induced TNF and IL-6 production via AP-1.
Journal of immunology (Baltimore, Md. : 1950)
Smolinska MJ,Page TH,Urbaniak AM,Mutch BE,Horwood NJ
Thu Dec 01 00:00:00 EST 2011
Flemingia macrophylla Extract Ameliorates Experimental Osteoporosis in Ovariectomized Rats.
Evidence-based complementary and alternative medicine : eCAM
Ho HY,Wu JB,Lin WC
Thu Aug 23 00:00:00 EDT 2012
Siglecs facilitate HIV-1 infection of macrophages through adhesion with viral sialic acids.
PloS one
Zou Z,Chastain A,Moir S,Ford J,Trandem K,Martinelli E,Cicala C,Crocker P,Arthos J,Sun PD
Fri Jun 08 00:00:00 EDT 2012
The transient receptor potential ion channel TRPV6 is expressed at low levels in osteoblasts and has little role in osteoblast calcium uptake.
PloS one
Little R,Muimo R,Robson L,Harris K,Grabowski PS
Fri May 11 00:00:00 EDT 2012