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Product Details
PV4175
Product Specifications
Species
Human
Expression System
Insect cells
Amino acid sequence
Full length
Tag
GST-tag
Molecular weight
102.8 kDa
Class
Recombinant
Type
Protein
Conjugate
Form
Liquid
Concentration
See Label
Purification
purified
Storage buffer
50mM tris, pH 7.5, with 0.5mM EDTA, 150mM NaCl, 2mM DTT, 50% glycerol, 0.02% Triton X-100
Contains
no preservative
Storage conditions
-80° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Dry ice
Product Specific Information
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 µg, 10 µg and 20 µg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 µL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase.
Protein Form: Full Length
Target Information
MARK4 is a serine/threonine kinase that is likely to be directly involved in microtubule organization in neuronal cells. The encoded protein is associated with the centrosome throughout mitosis and may be involved in cell cycle control. Expression of MARK4 is a potential marker for cancer, and the encoded protein may also play a role in Alzheimer's disease. Pseudogenes of MARK4 are located on both the short and long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for MARK4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
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Bioinformatics
Protein Aliases: FLJ90097; MAP/microtubule affinity-regulating kinase 4; MAP/microtubule affinity-regulating kinase like 1; MAP/microtubule affinity-regulating kinase-like 1; MARK4 serine/threonine protein kinase; Nbla00650
Gene Aliases: KIAA1860; MARK4; MARK4L; MARK4S; MARKL1; MARKL1L; PAR-1D
UniProt ID: (Human) Q96L34
Entrez Gene ID: (Human) 57787
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