Product References
Deletion of Nox4 enhances remyelination following cuprizone-induced demyelination by increasing phagocytic capacity of microglia and macrophages in mice.
Glia
Yamanaka K,Nakamura K,Shibahara T,Takashima M,Takaki H,Hidaka M,Komori M,Yoshikawa Y,Wakisaka Y,Ago T,Kitazono T
100-13A was used in Cell Culture to examine the effect of Nox4 deletion on demyelination-remyelination, the most common pathological change in the brain.
Wed Mar 01 00:00:00 EST 2023
An engineered Sox17 induces somatic to neural stem cell fate transitions independently from pluripotency reprogramming.
Science advances
Weng M,Hu H,Graus MS,Tan DS,Gao Y,Ren S,Ho DHH,Langer J,Holzner M,Huang Y,Ling GS,Lai CSW,Francois M,Jauch R
100-13A was used in In vitro experiments to report iNSC reprogramming from embryonic and aged mouse fibroblasts as well as from human blood using an engineered Sox17 (eSox17FNV).
Fri Aug 25 00:00:00 EDT 2023
Myelination- and migration-associated genes are downregulated after phagocytosis in cultured oligodendrocyte precursor cells.
Journal of neurochemistry
Hamanaka G,Hernández IC,Takase H,Ishikawa H,Benboujja F,Kimura S,Fukuda N,Guo S,Lok J,Lo EH,Arai K
100-13A was used in Cell Culture to show that cultured OPCs phagocytosed myelin-debris-rich lysates prepared from rat corpus callosum, without progressing to cell death.
Wed Nov 01 00:00:00 EDT 2023
Three-dimensional co-culture platform of human induced pluripotent stem cell-derived oligodendrocyte lineage cells and neurons for studying myelination.
STAR protocols
von der Bey M,De Cicco S,Zach S,Hengerer B,Ercan-Herbst E
100-13A was used in In vitro experiments to describe steps to differentiate hiPSCs into cortical neurons and oligodendrocyte lineage cells on 3D nanofibers.
Fri Mar 17 00:00:00 EDT 2023
A cholinergic neuroskeletal interface promotes bone formation during postnatal growth and exercise.
Cell stem cell
Gadomski S,Fielding C,García-García A,Korn C,Kapeni C,Ashraf S,Villadiego J,Toro RD,Domingues O,Skepper JN,Michel T,Zimmer J,Sendtner R,Dillon S,Poole KES,Holdsworth G,Sendtner M,Toledo-Aral JJ,De Bari C,McCaskie AW,Robey PG,Méndez-Ferrer S
100-13A was used in Cell Culture to uncover a cholinergic neuro-osteocyte interface that regulates skeletogenesis and skeletal turnover through bone-anabolic effects.
Thu Apr 07 00:00:00 EDT 2022
Platelet-Derived Growth Factor-Functionalized Scaffolds for the Recruitment of Synovial Mesenchymal Stem Cells for Osteochondral Repair.
Stem cells international
Luo Y,Cao X,Chen J,Gu J,Yu H,Sun J,Zou J
Tue Feb 08 00:00:00 EST 2022
Coactivator-associated arginine methyltransferase 1 controls oligodendrocyte differentiation in the corpus callosum during early brain development.
Developmental neurobiology
Ishino Y,Shimizu S,Tohyama M,Miyata S
100-13A was used in Cell Culture to propose that Carm1 is an essential molecule for the development of OPCs and OLs during brain development.
Fri Apr 01 00:00:00 EDT 2022
OCT4-induced oligodendrocyte progenitor cells promote remyelination and ameliorate disease.
NPJ Regenerative medicine
Yun W,Choi KA,Hwang I,Zheng J,Park M,Hong W,Jang AY,Kim JH,Choi W,Kim DS,Kim IY,Kim YJ,Liu Y,Yoon BS,Park G,Song G,Hong S,You S
Thu Jan 13 00:00:00 EST 2022
Young CSF restores oligodendrogenesis and memory in aged mice via Fgf17.
Nature
Iram T,Kern F,Kaur A,Myneni S,Morningstar AR,Shin H,Garcia MA,Yerra L,Palovics R,Yang AC,Hahn O,Lu N,Shuken SR,Haney MS,Lehallier B,Iyer M,Luo J,Zetterberg H,Keller A,Zuchero JB,Wyss-Coray T
100-13A was used in Cell Culture to demonstrate the rejuvenating power of young CSF and identify Fgf17 as a key target to restore oligodendrocyte function in the ageing brain.
Sun May 01 00:00:00 EDT 2022
The Extracellular Matrix Proteins Tenascin-C and Tenascin-R Retard Oligodendrocyte Precursor Maturation and Myelin Regeneration in a Cuprizone-Induced Long-Term Demyelination Animal Model.
Cells
Bauch J,Faissner A
100-13A was used in Cell Culture to study how tenascins interfere with remyelination in vivo.
Sat May 28 00:00:00 EDT 2022
Context-dependent tumor-suppressive BMP signaling in diffuse intrinsic pontine glioma regulates stemness through epigenetic regulation of CXXC5.
Nature cancer
Sun Y,Yan K,Wang Y,Xu C,Wang D,Zhou W,Guo S,Han Y,Tang L,Shao Y,Shan S,Zhang QC,Tang Y,Zhang L,Xi Q
100-13A was used in Cell Culture to show how BMP signaling impacts diffuse intrinsic pontine glioma (DIPG) and identifies the potent antitumor efficacy of Dacinostat for DIPG.
Thu Sep 01 00:00:00 EDT 2022
CNS myelination requires VAMP2/3-mediated membrane expansion in oligodendrocytes.
Nature communications
Lam M,Takeo K,Almeida RG,Cooper MH,Wu K,Iyer M,Kantarci H,Zuchero JB
100-13A was used in Cell Culture to study how CNS myelin membrane addition requires exocytosis mediated by the vesicular SNARE proteins VAMP2/3.
Fri Sep 23 00:00:00 EDT 2022
CNS myelination requires VAMP2/3-mediated membrane expansion in oligodendrocytes.
Nature communications
Lam M,Takeo K,Almeida RG,Cooper MH,Wu K,Iyer M,Kantarci H,Zuchero JB
100-13A was used in Cell Culture to study how CNS myelin membrane addition requires exocytosis mediated by the vesicular SNARE proteins VAMP2/3.
Fri Sep 23 00:00:00 EDT 2022
Neurotoxic reactive astrocytes induce cell death via saturated lipids.
Nature
Guttenplan KA,Weigel MK,Prakash P,Wijewardhane PR,Hasel P,Rufen-Blanchette U,Münch AE,Blum JA,Fine J,Neal MC,Bruce KD,Gitler AD,Chopra G,Liddelow SA,Barres BA
Mon Nov 01 00:00:00 EDT 2021
H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model.
Cancer cell
Haag D,Mack N,Benites Goncalves da Silva P,Statz B,Clark J,Tanabe K,Sharma T,Jäger N,Jones DTW,Kawauchi D,Wernig M,Pfister SM
Mon Mar 08 00:00:00 EST 2021
Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis.
Cell stem cell
Leimkühler NB,Gleitz HFE,Ronghui L,Snoeren IAM,Fuchs SNR,Nagai JS,Banjanin B,Lam KH,Vogl T,Kuppe C,Stalmann USA,Büsche G,Kreipe H,Gütgemann I,Krebs P,Banz Y,Boor P,Tai EW,Brümmendorf TH,Koschmieder S,Crysandt M,Bindels E,Kramann R,Costa IG,Schneider RK
Thu Apr 01 00:00:00 EDT 2021
Oligodendroglial ring finger protein Rnf43 is an essential injury-specific regulator of oligodendrocyte maturation.
Neuron
Niu J,Yu G,Wang X,Xia W,Wang Y,Hoi KK,Mei F,Xiao L,Chan JR,Fancy SPJ
Wed Oct 06 00:00:00 EDT 2021
Histamine H2 receptor negatively regulates oligodendrocyte differentiation in neonatal hypoxic-ischemic white matter injury.
The Journal of experimental medicine
Jiang L,Cheng L,Chen H,Dai H,An D,Ma Q,Zheng Y,Zhang X,Hu W,Chen Z
Mon Jan 04 00:00:00 EST 2021
BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes.
Autophagy
Yazdankhah M,Ghosh S,Shang P,Stepicheva N,Hose S,Liu H,Chamling X,Tian S,Sullivan MLG,Calderon MJ,Fitting CS,Weiss J,Jayagopal A,Handa JT,Sahel JA,Zigler JS,Kinchington PR,Zack DJ,Sinha D
100-13A was used in Sample Preparation (FC/FACS) to investigate mechanisms of oligodendrocyte progenitor cell differentiation to identify treatment options.
Fri Oct 01 00:00:00 EDT 2021
Intranasal mesenchymal stem cell therapy to boost myelination after encephalopathy of prematurity.
Glia
Vaes JEG,van Kammen CM,Trayford C,van der Toorn A,Ruhwedel T,Benders MJNL,Dijkhuizen RM,Möbius W,van Rijt SH,Nijboer CH
Mon Mar 01 00:00:00 EST 2021
Intranasal mesenchymal stem cell therapy to boost myelination after encephalopathy of prematurity.
Glia
Vaes JEG,van Kammen CM,Trayford C,van der Toorn A,Ruhwedel T,Benders MJNL,Dijkhuizen RM,Möbius W,van Rijt SH,Nijboer CH
Mon Mar 01 00:00:00 EST 2021
A robust culture system to generate neural progenitors with gliogenic competence from clinically relevant induced pluripotent stem cells for treatment of spinal cord injury.
Stem cells translational medicine
Kamata Y,Isoda M,Sanosaka T,Shibata R,Ito S,Okubo T,Shinozaki M,Inoue M,Koya I,Shibata S,Shindo T,Matsumoto M,Nakamura M,Okano H,Nagoshi N,Kohyama J
Mon Mar 01 00:00:00 EST 2021
Defining the regenerative effects of native spider silk fibers on primary Schwann cells, sensory neurons, and nerve-associated fibroblasts.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Millesi F,Weiss T,Mann A,Haertinger M,Semmler L,Supper P,Pils D,Naghilou A,Radtke C
Mon Feb 01 00:00:00 EST 2021
Extracellular NLRP3 inflammasome particles are internalized by human coronary artery smooth muscle cells and induce pro-atherogenic effects.
Scientific reports
Gaul S,Schaeffer KM,Opitz L,Maeder C,Kogel A,Uhlmann L,Kalwa H,Wagner U,Haas J,Behzadi A,Pelegrin P,Boeckel JN,Laufs U
Mon Jul 26 00:00:00 EDT 2021
Focused ultrasound mediated blood-brain barrier opening is safe and feasible in a murine pontine glioma model.
Scientific reports
Englander ZK,Wei HJ,Pouliopoulos AN,Bendau E,Upadhyayula P,Jan CI,Spinazzi EF,Yoh N,Tazhibi M,McQuillan NM,Wang TJC,Bruce JN,Canoll P,Feldstein NA,Zacharoulis S,Konofagou EE,Wu CC
Mon Mar 22 00:00:00 EDT 2021
Altered Neuronal Support and Inflammatory Response in Bipolar Disorder Patient-Derived Astrocytes.
Stem cell reports
Vadodaria KC,Mendes APD,Mei A,Racha V,Erikson G,Shokhirev MN,Oefner R,Heard KJ,McCarthy MJ,Eyler L,Kelsoe JR,Santos R,Marchetto MC,Gage FH
Tue Apr 13 00:00:00 EDT 2021
An implantable human stem cell-derived tissue-engineered rostral migratory stream for directed neuronal replacement.
Communications biology
O'Donnell JC,Purvis EM,Helm KVT,Adewole DO,Zhang Q,Le AD,Cullen DK
Thu Jul 15 00:00:00 EDT 2021
Select neurotrophins promote oligodendrocyte progenitor cell process outgrowth in the presence of chondroitin sulfate proteoglycans.
Journal of neuroscience research
Siebert JR,Osterhout DJ
Thu Apr 01 00:00:00 EDT 2021
Autologous transplantation of thecal stem cells restores ovarian function in nonhuman primates.
Cell discovery
Chen H,Xia K,Huang W,Li H,Wang C,Ma Y,Chen J,Luo P,Zheng S,Wang J,Wang Y,Dong L,Tan Z,Lai X,Mao FF,Li W,Liang X,Wang T,Xiang AP,Ke Q
Tue Aug 31 00:00:00 EDT 2021
Protocol for mouse adult neural stem cell isolation and culture.
STAR protocols
Ahmed AKMA,Isaksen TJ,Yamashita T
Fri Jun 18 00:00:00 EDT 2021
Overcoming the inhibitory microenvironment surrounding oligodendrocyte progenitor cells following experimental demyelination.
Nature communications
Saraswat D,Shayya HJ,Polanco JJ,Tripathi A,Welliver RR,Pol SU,Seidman RA,Broome JE,O'Bara MA,van Kuppervelt TH,Phillips JJ,Dutta R,Sim FJ
Fri Mar 26 00:00:00 EDT 2021
Overcoming the inhibitory microenvironment surrounding oligodendrocyte progenitor cells following experimental demyelination.
Nature communications
Saraswat D,Shayya HJ,Polanco JJ,Tripathi A,Welliver RR,Pol SU,Seidman RA,Broome JE,O'Bara MA,van Kuppervelt TH,Phillips JJ,Dutta R,Sim FJ
Fri Mar 26 00:00:00 EDT 2021
Overcoming the inhibitory microenvironment surrounding oligodendrocyte progenitor cells following experimental demyelination.
Nature communications
Saraswat D,Shayya HJ,Polanco JJ,Tripathi A,Welliver RR,Pol SU,Seidman RA,Broome JE,O'Bara MA,van Kuppervelt TH,Phillips JJ,Dutta R,Sim FJ
Fri Mar 26 00:00:00 EDT 2021
Curcumin promotes oligodendrocyte differentiation and their protection against TNF-α through the activation of the nuclear receptor PPAR-γ.
Scientific reports
Bernardo A,Plumitallo C,De Nuccio C,Visentin S,Minghetti L
Tue Mar 02 00:00:00 EST 2021
Neuroblastoma and DIPG Organoid Coculture System for Personalized Assessment of Novel Anticancer Immunotherapies.
Journal of personalized medicine
M Kholosy W,Derieppe M,van den Ham F,Ober K,Su Y,Custers L,Schild L,M J van Zogchel L,M Wellens L,R Ariese H,Szanto CL,Wienke J,Dierselhuis MP,van Vuurden D,Dolman EM,Molenaar JJ
100-13A was used in Cell Culture to provide a procedure for the establishment of an ex vivo test coculture system of paediatric tumour organoids and immune cells that enables the assessment of different immunotherpay approaches in paediatric tumour organoids.
Mon Aug 30 00:00:00 EDT 2021
Origins and Proliferative States of Human Oligodendrocyte Precursor Cells.
Cell
Huang W,Bhaduri A,Velmeshev D,Wang S,Wang L,Rottkamp CA,Alvarez-Buylla A,Rowitch DH,Kriegstein AR
100-13A was used in Cell Culture to indicate properties of OPC derivation, proliferation, and dispersion important for human white matter expansion and myelination.
Thu Aug 06 00:00:00 EDT 2020
m6A mRNA Methylation Is Essential for Oligodendrocyte Maturation and CNS Myelination.
Neuron
Xu H,Dzhashiashvili Y,Shah A,Kunjamma RB,Weng YL,Elbaz B,Fei Q,Jones JS,Li YI,Zhuang X,Ming GL,He C,Popko B
Wed Jan 22 00:00:00 EST 2020
The fatty acid binding protein FABP7 is required for optimal oligodendrocyte differentiation during myelination but not during remyelination.
Glia
Foerster S,Guzman de la Fuente A,Kagawa Y,Bartels T,Owada Y,Franklin RJM
Wed Jul 01 00:00:00 EDT 2020
The formation of paranodal spirals at the ends of CNS myelin sheaths requires the planar polarity protein Vangl2.
Glia
Jarjour AA,Velichkova AN,Boyd A,Lord KM,Torsney C,Henderson DJ,Ffrench-Constant C
Tue Sep 01 00:00:00 EDT 2020
Effects of miR-219/miR-338 on microglia and astrocyte behaviors and astrocyte-oligodendrocyte precursor cell interactions.
Neural regeneration research
Nguyen LH,Ong W,Wang K,Wang M,Nizetic D,Chew SY
100-13A was used in Cell Culture to study the effects of miR-219/miR-338 treatment on microglia and astrocytes in vitro and in vivo and suggest that miR-219/miR-338 as a promising treatment for axonal remyelination in the CNS following nerve injuries.
Wed Apr 01 00:00:00 EDT 2020
Growth factors-based beneficial effects of platelet lysate on umbilical cord-derived stem cells and their synergistic use in osteoarthritis treatment.
Cell death & disease
Yan L,Zhou L,Yan B,Zhang L,Du W,Liu F,Yuan Q,Tong P,Shan L,Efferth T
Wed Oct 14 00:00:00 EDT 2020
Multicellular 3D Neurovascular Unit Model for Assessing Hypoxia and Neuroinflammation Induced Blood-Brain Barrier Dysfunction.
Scientific reports
Nzou G,Wicks RT,VanOstrand NR,Mekky GA,Seale SA,El-Taibany A,Wicks EE,Nechtman CM,Marrotte EJ,Makani VS,Murphy SV,Seeds MC,Jackson JD,Atala AJ
Wed Jun 17 00:00:00 EDT 2020
Generation of oligodendrocytes and establishment of an all-human myelinating platform from human pluripotent stem cells.
Nature protocols
García-León JA,García-Díaz B,Eggermont K,Cáceres-Palomo L,Neyrinck K,Madeiro da Costa R,Dávila JC,Baron-Van Evercooren A,Gutiérrez A,Verfaillie CM
Sun Nov 01 00:00:00 EDT 2020
Gab1 mediates PDGF signaling and is essential to oligodendrocyte differentiation and CNS myelination.
eLife
Zhou L,Shao CY,Xie YJ,Wang N,Xu SM,Luo BY,Wu ZY,Ke YH,Qiu M,Shen Y
100-13A was used in Sample Preparation (Western Blotting) to investigate platelet-derived growth factor signaling in oligodendrocyte precursor cells.
Thu Jan 16 00:00:00 EST 2020
Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells.
Cell stem cell
Neumann B,Baror R,Zhao C,Segel M,Dietmann S,Rawji KS,Foerster S,McClain CR,Chalut K,van Wijngaarden P,Franklin RJM
100-13A was used in Cell Culture to provide insight into aging-associated remyelination failure and suggest therapeutic interventions for reversing such declines in chronic disease.
Thu Oct 03 00:00:00 EDT 2019
Oligodendrocyte Death in Pelizaeus-Merzbacher Disease Is Rescued by Iron Chelation.
Cell stem cell
Nobuta H,Yang N,Ng YH,Marro SG,Sabeur K,Chavali M,Stockley JH,Killilea DW,Walter PB,Zhao C,Huie P,Goldman SA,Kriegstein AR,Franklin RJM,Rowitch DH,Wernig M
100-13A was used in Cell Culture to demonstrate that patient-derived oligodendrocytes can develop to the pre-myelinating stage, but subsequently undergo cell death using induced pluripotent stem cell (iPSC) and gene-correction.
Thu Oct 03 00:00:00 EDT 2019
PTEN-induced partial epithelial-mesenchymal transition drives diabetic kidney disease.
The Journal of clinical investigation
Li Y,Hu Q,Li C,Liang K,Xiang Y,Hsiao H,Nguyen TK,Park PK,Egranov SD,Ambati CR,Putluri N,Hawke DH,Han L,Hung MC,Danesh FR,Yang L,Lin C
Fri Mar 01 00:00:00 EST 2019
Nucleoporin Seh1 Interacts with Olig2/Brd7 to Promote Oligodendrocyte Differentiation and Myelination.
Neuron
Liu Z,Yan M,Liang Y,Liu M,Zhang K,Shao D,Jiang R,Li L,Wang C,Nussenzveig DR,Zhang K,Chen S,Zhong C,Mo W,Fontoura BMA,Zhang L
Wed May 08 00:00:00 EDT 2019
Pioneer Factor NeuroD1 Rearranges Transcriptional and Epigenetic Profiles to Execute Microglia-Neuron Conversion.
Neuron
Matsuda T,Irie T,Katsurabayashi S,Hayashi Y,Nagai T,Hamazaki N,Adefuin AMD,Miura F,Ito T,Kimura H,Shirahige K,Takeda T,Iwasaki K,Imamura T,Nakashima K
Wed Feb 06 00:00:00 EST 2019
Familial t(1;11) translocation is associated with disruption of white matter structural integrity and oligodendrocyte-myelin dysfunction.
Molecular psychiatry
Vasistha NA,Johnstone M,Barton SK,Mayerl SE,Thangaraj Selvaraj B,Thomson PA,Dando O,Grünewald E,Alloza C,Bastin ME,Livesey MR,Economides K,Magnani D,Makedonopolou P,Burr K,Story DJ,Blackwood DHR,Wyllie DJA,McIntosh AM,Millar JK,Ffrench-Constant C,Hardingham GE,Lawrie SM,Chandran S
Fri Nov 01 00:00:00 EDT 2019
Src and SHP2 coordinately regulate the dynamics and organization of vimentin filaments during cell migration.
Oncogene
Yang CY,Chang PW,Hsu WH,Chang HC,Chen CL,Lai CC,Chiu WT,Chen HC
Wed May 01 00:00:00 EDT 2019
Aging restricts the ability of mesenchymal stem cells to promote the generation of oligodendrocytes during remyelination.
Glia
Rivera FJ,de la Fuente AG,Zhao C,Silva ME,Gonzalez GA,Wodnar R,Feichtner M,Lange S,Errea O,Priglinger E,O'Sullivan A,Romanelli P,Jadasz JJ,Brachtl G,Greil R,Tempfer H,Traweger A,Bátiz LF,Küry P,Couillard-Despres S,Franklin RJM,Aigner L
Thu Aug 01 00:00:00 EDT 2019
Low sulfated heparins target multiple proteins for central nervous system repair.
Glia
McCanney GA,McGrath MA,Otto TD,Burchmore R,Yates EA,Bavington CD,Willison HJ,Turnbull JE,Barnett SC
Mon Apr 01 00:00:00 EDT 2019
Astrocyte-to-astrocyte contact and a positive feedback loop of growth factor signaling regulate astrocyte maturation.
Glia
Li J,Khankan RR,Caneda C,Godoy MI,Haney MS,Krawczyk MC,Bassik MC,Sloan SA,Zhang Y
Thu Aug 01 00:00:00 EDT 2019
Perfluorocarbon Labeling of Human Glial-Restricted Progenitors for 19 F Magnetic Resonance Imaging.
Stem cells translational medicine
Richard JP,Hussain U,Gross S,Taga A,Kouser M,Almad A,Campanelli JT,Bulte JWM,Maragakis NJ
Mon Apr 01 00:00:00 EDT 2019
Extracellular Vesicles from Activated Dermal Fibroblasts Stimulate Hair Follicle Growth Through Dermal Papilla-Secreted Norrin.
Stem cells (Dayton, Ohio)
le Riche A,Aberdam E,Marchand L,Frank E,Jahoda C,Petit I,Bordes S,Closs B,Aberdam D
Sun Sep 01 00:00:00 EDT 2019
Smooth muscle cell-specific knockout of neuropilin-1 impairs postnatal lung development and pathological vascular smooth muscle cell accumulation.
American journal of physiology. Cell physiology
Mahmoud M,Evans IM,Mehta V,Pellet-Many C,Paliashvili K,Zachary I
Fri Mar 01 00:00:00 EST 2019
GAIN domain-mediated cleavage is required for activation of G protein-coupled receptor 56 (GPR56) by its natural ligands and a small-molecule agonist.
The Journal of biological chemistry
Zhu B,Luo R,Jin P,Li T,Oak HC,Giera S,Monk KR,Lak P,Shoichet BK,Piao X
Fri Dec 13 00:00:00 EST 2019
Cell Type-Specific Interferon-γ-mediated Antagonism of KSHV Lytic Replication.
Scientific reports
Park MK,Cho H,Roh SW,Kim SJ,Myoung J
Wed Feb 20 00:00:00 EST 2019
M2 receptors activation modulates cell growth, migration and differentiation of rat Schwann-like adipose-derived stem cells.
Cell death discovery
Piovesana R,Faroni A,Magnaghi V,Reid AJ,Tata AM
Wed Sep 30 00:00:00 EDT 2020
Adenosine A2A receptor stimulation restores cell functions and differentiation in Niemann-Pick type C-like oligodendrocytes.
Scientific reports
De Nuccio C,Bernardo A,Ferrante A,Pepponi R,Martire A,Falchi M,Visentin S,Popoli P,Minghetti L
Fri Jul 05 00:00:00 EDT 2019
Combinatory Multifactor Treatment Effects on Primary Nanofiber Oligodendrocyte Cultures.
Cells
Enz LS,Zeis T,Hauck A,Linington C,Schaeren-Wiemers N
100-13A was used in In vitro experiments to investigate the molecular mechanisms of myelation in multiple sclerosis for more accurate models in treatment development.
Tue Nov 12 00:00:00 EST 2019
Schwann cells, but not Oligodendrocytes, Depend Strictly on Dynamin 2 Function.
eLife
Gerber D,Ghidinelli M,Tinelli E,Somandin C,Gerber J,Pereira JA,Ommer A,Figlia G,Miehe M,Nägeli LG,Suter V,Tadini V,Sidiropoulos PN,Wessig C,Toyka KV,Suter U
100-13A was used in Cell Culture to study the effects of dynamin 2 deletion on oligodendrocytes and Schwann cells.
Wed Jan 16 00:00:00 EST 2019
NG2 as an Identity and Quality Marker of Mesenchymal Stem Cell Extracellular Vesicles.
Cells
Barilani M,Peli V,Cherubini A,Dossena M,Dolo V,Lazzari L
100-13A was used in In vitro experiments to study antigen expression of cord blood and bone marrow mesenchymal stem cells (MSCs) and released extracellular vesicles (EVs) to define an identity and quality parameter of MSC EV as a medicinal product in the context of clinical applications.
Wed Nov 27 00:00:00 EST 2019
Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis.
Nature medicine
Falcão AM,van Bruggen D,Marques S,Meijer M,Jäkel S,Agirre E,Floriddia EM,Vanichkina DP,Ffrench-Constant C,Williams A,Guerreiro-Cacais AO,Castelo-Branco G
100-13A was used in In vitro experiments to investigate the genes in oligodendrocytes in experimental autoimmune encephalomyelitis from multiple sclerosis.
Sat Dec 01 00:00:00 EST 2018
Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy.
The Journal of experimental medicine
Chheda ZS,Kohanbash G,Okada K,Jahan N,Sidney J,Pecoraro M,Yang X,Carrera DA,Downey KM,Shrivastav S,Liu S,Lin Y,Lagisetti C,Chuntova P,Watchmaker PB,Mueller S,Pollack IF,Rajalingam R,Carcaboso AM,Mann M,Sette A,Garcia KC,Hou Y,Okada H
100-13A was used in Cell Culture to assess whether targeting the neoantigen resulting from the histone 3 variant H3.3K27M mutation is therapeutically viable in T cell-based therapy for glioma.
Tue Jan 02 00:00:00 EST 2018
Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy.
The Journal of experimental medicine
Chheda ZS,Kohanbash G,Okada K,Jahan N,Sidney J,Pecoraro M,Yang X,Carrera DA,Downey KM,Shrivastav S,Liu S,Lin Y,Lagisetti C,Chuntova P,Watchmaker PB,Mueller S,Pollack IF,Rajalingam R,Carcaboso AM,Mann M,Sette A,Garcia KC,Hou Y,Okada H
100-13A was used in Cell Culture to assess whether targeting the neoantigen resulting from the histone 3 variant H3.3K27M mutation is therapeutically viable in T cell-based therapy for glioma.
Tue Jan 02 00:00:00 EST 2018
Differences in neural stem cell identity and differentiation capacity drive divergent regenerative outcomes in lizards and salamanders.
Proceedings of the National Academy of Sciences of the United States of America
Sun AX,Londono R,Hudnall ML,Tuan RS,Lozito TP
Tue Aug 28 00:00:00 EDT 2018
Differences in neural stem cell identity and differentiation capacity drive divergent regenerative outcomes in lizards and salamanders.
Proceedings of the National Academy of Sciences of the United States of America
Sun AX,Londono R,Hudnall ML,Tuan RS,Lozito TP
Tue Aug 28 00:00:00 EDT 2018
Differences in neural stem cell identity and differentiation capacity drive divergent regenerative outcomes in lizards and salamanders.
Proceedings of the National Academy of Sciences of the United States of America
Sun AX,Londono R,Hudnall ML,Tuan RS,Lozito TP
Tue Aug 28 00:00:00 EDT 2018
p53 and NF 1 loss plays distinct but complementary roles in glioma initiation and progression.
Glia
Gonzalez PP,Kim J,Galvao RP,Cruickshanks N,Abounader R,Zong H
100-13A was used in Cell Culture to investigate cell of origin evolution in glioma.
Tue May 01 00:00:00 EDT 2018
Neurotrophically Induced Mesenchymal Progenitor Cells Derived from Induced Pluripotent Stem Cells Enhance Neuritogenesis via Neurotrophin and Cytokine Production.
Stem cells translational medicine
Brick RM,Sun AX,Tuan RS
Mon Jan 01 00:00:00 EST 2018
Interactive Repression of MYRF Self-Cleavage and Activity in Oligodendrocyte Differentiation by TMEM98 Protein.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Huang H,Teng P,Du J,Meng J,Hu X,Tang T,Zhang Z,Qi YB,Qiu M
100-13A was used in Cell Culture to study how TMEM98, an endoplasmic reticulum (ER)-associated transmembrane protein, is capable of binding to the C-terminal of myelin regulatory factor (MYRF) and inhibiting its self-cleavage and N-fragment nuclear translocation to provide insight into the molecular regulation of oligodendrocytes (OL) differentiation and myelinogenesis.
Wed Nov 14 00:00:00 EST 2018
Neuroprotective Effects of Human Mesenchymal Stem Cells and Platelet-Derived Growth Factor on Human Retinal Ganglion Cells.
Stem cells (Dayton, Ohio)
Osborne A,Sanderson J,Martin KR
Mon Jan 01 00:00:00 EST 2018
CLC-2 is a positive modulator of oligodendrocyte precursor cell differentiation and myelination.
Molecular medicine reports
Hou X,Zhang R,Wang J,Li Y,Li F,Zhang Y,Zheng X,Shen Y,Wang Y,Zhou L
100-13A was used in Cell Culture to investigate oligodendrocyte differentiation to understand myelation.
Thu Mar 01 00:00:00 EST 2018
PDGF-mediated mesenchymal transformation renders endothelial resistance to anti-VEGF treatment in glioblastoma.
Nature communications
Liu T,Ma W,Xu H,Huang M,Zhang D,He Z,Zhang L,Brem S,O'Rourke DM,Gong Y,Mou Y,Zhang Z,Fan Y
Mon Aug 27 00:00:00 EDT 2018
Nfat/calcineurin signaling promotes oligodendrocyte differentiation and myelination by transcription factor network tuning.
Nature communications
Weider M,Starost LJ,Groll K,Küspert M,Sock E,Wedel M,Fröb F,Schmitt C,Baroti T,Hartwig AC,Hillgärtner S,Piefke S,Fadler T,Ehrlich M,Ehlert C,Stehling M,Albrecht S,Jabali A,Schöler HR,Winkler J,Kuhlmann T,Wegner M
Fri Mar 02 00:00:00 EST 2018
Nfat/calcineurin signaling promotes oligodendrocyte differentiation and myelination by transcription factor network tuning.
Nature communications
Weider M,Starost LJ,Groll K,Küspert M,Sock E,Wedel M,Fröb F,Schmitt C,Baroti T,Hartwig AC,Hillgärtner S,Piefke S,Fadler T,Ehrlich M,Ehlert C,Stehling M,Albrecht S,Jabali A,Schöler HR,Winkler J,Kuhlmann T,Wegner M
Fri Mar 02 00:00:00 EST 2018
Nfat/calcineurin signaling promotes oligodendrocyte differentiation and myelination by transcription factor network tuning.
Nature communications
Weider M,Starost LJ,Groll K,Küspert M,Sock E,Wedel M,Fröb F,Schmitt C,Baroti T,Hartwig AC,Hillgärtner S,Piefke S,Fadler T,Ehrlich M,Ehlert C,Stehling M,Albrecht S,Jabali A,Schöler HR,Winkler J,Kuhlmann T,Wegner M
Fri Mar 02 00:00:00 EST 2018
Lgl1 controls NG2 endocytic pathway to regulate oligodendrocyte differentiation and asymmetric cell division and gliomagenesis.
Nature communications
Daynac M,Chouchane M,Collins HY,Murphy NE,Andor N,Niu J,Fancy SPJ,Stallcup WB,Petritsch CK
Tue Aug 21 00:00:00 EDT 2018
3D bio-printed scaffold-free nerve constructs with human gingiva-derived mesenchymal stem cells promote rat facial nerve regeneration.
Scientific reports
Zhang Q,Nguyen PD,Shi S,Burrell JC,Cullen DK,Le AD
Thu Apr 26 00:00:00 EDT 2018
TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets.
Nature communications
Decaesteker B,Denecker G,Van Neste C,Dolman EM,Van Loocke W,Gartlgruber M,Nunes C,De Vloed F,Depuydt P,Verboom K,Rombaut D,Loontiens S,De Wyn J,Kholosy WM,Koopmans B,Essing AHW,Herrmann C,Dreidax D,Durinck K,Deforce D,Van Nieuwerburgh F,Henssen A,Versteeg R,Boeva V,Schleiermacher G,van Nes J,Mestdagh P,Vanhauwaert S,Schulte JH,Westermann F,Molenaar JJ,De Preter K,Speleman F
Mon Nov 19 00:00:00 EST 2018
Degradation of the endoplasmic reticulum-anchored transcription factor MyRF by the ubiquitin ligase SCFFbxw7 in a manner dependent on the kinase GSK-3.
The Journal of biological chemistry
Nakayama S,Yumimoto K,Kawamura A,Nakayama KI
Fri Apr 13 00:00:00 EDT 2018
Grey matter OPCs are less mature and less sensitive to IFNγ than white matter OPCs: consequences for remyelination.
Scientific reports
Lentferink DH,Jongsma JM,Werkman I,Baron W
Thu Feb 01 00:00:00 EST 2018
Engineered 3D-printed artificial axons.
Scientific reports
Espinosa-Hoyos D,Jagielska A,Homan KA,Du H,Busbee T,Anderson DG,Fang NX,Lewis JA,Van Vliet KJ
Thu Jan 11 00:00:00 EST 2018
Human Cortex Spheroid with a Functional Blood Brain Barrier for High-Throughput Neurotoxicity Screening and Disease Modeling.
Scientific reports
Nzou G,Wicks RT,Wicks EE,Seale SA,Sane CH,Chen A,Murphy SV,Jackson JD,Atala AJ
Wed May 09 00:00:00 EDT 2018
Fibrinogen Activates BMP Signaling in Oligodendrocyte Progenitor Cells and Inhibits Remyelination after Vascular Damage.
Neuron
Petersen MA,Ryu JK,Chang KJ,Etxeberria A,Bardehle S,Mendiola AS,Kamau-Devers W,Fancy SPJ,Thor A,Bushong EA,Baeza-Raja B,Syme CA,Wu MD,Rios Coronado PE,Meyer-Franke A,Yahn S,Pous L,Lee JK,Schachtrup C,Lassmann H,Huang EJ,Han MH,Absinta M,Reich DS,Ellisman MH,Rowitch DH,Chan JR,Akassoglou K
Wed Dec 06 00:00:00 EST 2017
Neuronal CTGF/CCN2 negatively regulates myelination in a mouse model of tuberous sclerosis complex.
The Journal of experimental medicine
Ercan E,Han JM,Di Nardo A,Winden K,Han MJ,Hoyo L,Saffari A,Leask A,Geschwind DH,Sahin M
100-13A was used in Cell Culture to highlight the role of mTOR-dependent signaling between neuronal and nonneuronal cells in the regulation of myelin.
Mon Mar 06 00:00:00 EST 2017
Tyrosine kinase inhibitor BIBF1120 ameliorates inflammation, angiogenesis and fibrosis in CCl4-induced liver fibrogenesis mouse model.
Scientific reports
Öztürk Akcora B,Storm G,Prakash J,Bansal R
Tue Mar 14 00:00:00 EDT 2017
LRP1 regulates peroxisome biogenesis and cholesterol homeostasis in oligodendrocytes and is required for proper CNS myelin development and repair.
eLife
Lin JP,Mironova YA,Shrager P,Giger RJ
100-13A was used in Cell Culture to reveal a novel role for low-density lipoprotein receptor-related protein-1 in peroxisome biogenesis, lipid homeostasis, and oligodendrocyte progenitor cell differentiation during white matter development and repair.
Mon Dec 18 00:00:00 EST 2017
A Brain Penetrant Mutant IDH1 Inhibitor Provides In Vivo Survival Benefit.
Scientific reports
Kopinja J,Sevilla RS,Levitan D,Dai D,Vanko A,Spooner E,Ware C,Forget R,Hu K,Kral A,Spacciapoli P,Kennan R,Jayaraman L,Pucci V,Perera S,Zhang W,Fischer C,Lam MH
Mon Oct 23 00:00:00 EDT 2017
Defined and Scalable Differentiation of Human Oligodendrocyte Precursors from Pluripotent Stem Cells in a 3D Culture System.
Stem cell reports
Rodrigues GMC,Gaj T,Adil MM,Wahba J,Rao AT,Lorbeer FK,Kulkarni RU,Diogo MM,Cabral JMS,Miller EW,Hockemeyer D,Schaffer DV
Tue Jun 06 00:00:00 EDT 2017
Histamine Receptor 3 negatively regulates oligodendrocyte differentiation and remyelination.
PloS one
Chen Y,Zhen W,Guo T,Zhao Y,Liu A,Rubio JP,Krull D,Richardson JC,Lu H,Wang R
100-13A was used in Cell Culture to provide evidence for H3R as a novel therapeutic target to promote remyelination in patients with multiple sclerosis.
Mon Jan 08 00:00:00 EST 2018
SHP-2-upregulated ZEB1 is important for PDGFRα-driven glioma epithelial-mesenchymal transition and invasion in mice and humans.
Oncogene
Zhang L,Zhang W,Li Y,Alvarez A,Li Z,Wang Y,Song L,Lv D,Nakano I,Hu B,Cheng SY,Feng H
Thu Oct 27 00:00:00 EDT 2016
Maturation and electrophysiological properties of human pluripotent stem cell-derived oligodendrocytes.
Stem cells (Dayton, Ohio)
Livesey MR,Magnani D,Cleary EM,Vasistha NA,James OT,Selvaraj BT,Burr K,Story D,Shaw CE,Kind PC,Hardingham GE,Wyllie DJ,Chandran S
Fri Apr 01 00:00:00 EDT 2016
Lysophosphatidic acid activates Arf6 to promote the mesenchymal malignancy of renal cancer.
Nature communications
Hashimoto S,Mikami S,Sugino H,Yoshikawa A,Hashimoto A,Onodera Y,Furukawa S,Handa H,Oikawa T,Okada Y,Oya M,Sabe H
Mon Feb 08 00:00:00 EST 2016
VCAM1 acts in parallel with CD69 and is required for the initiation of oligodendrocyte myelination.
Nature communications
Miyamoto Y,Torii T,Tanoue A,Yamauchi J
Wed Nov 23 00:00:00 EST 2016
Recovery from Toxic-Induced Demyelination Does Not Require the NG2 Proteoglycan.
PloS one
Albrecht S,Hagemeier K,Ehrlich M,Kemming C,Trotter J,Kuhlmann T
100-13A was used in In vitro experiments to influence the expression of genes, such as prostaglandin D2 synthase which has neuromodulatory properties.
Fri Nov 17 00:00:00 EST 2017
Recovery from Toxic-Induced Demyelination Does Not Require the NG2 Proteoglycan.
PloS one
Albrecht S,Hagemeier K,Ehrlich M,Kemming C,Trotter J,Kuhlmann T
100-13A was used in In vitro experiments to influence the expression of genes, such as prostaglandin D2 synthase which has neuromodulatory properties.
Fri Nov 17 00:00:00 EST 2017
Modulation of oligodendrocyte differentiation and maturation by combined biochemical and mechanical cues.
Scientific reports
Lourenço T,Paes de Faria J,Bippes CA,Maia J,Lopes-da-Silva JA,Relvas JB,Grãos M
Tue Feb 16 00:00:00 EST 2016
Cortical contractility triggers a stochastic switch to fast amoeboid cell motility.
Cell
Ruprecht V,Wieser S,Callan-Jones A,Smutny M,Morita H,Sako K,Barone V,Ritsch-Marte M,Sixt M,Voituriez R,Heisenberg CP
Thu Feb 12 00:00:00 EST 2015
Vitamin D receptor-retinoid X receptor heterodimer signaling regulates oligodendrocyte progenitor cell differentiation.
The Journal of cell biology
de la Fuente AG,Errea O,van Wijngaarden P,Gonzalez GA,Kerninon C,Jarjour AA,Lewis HJ,Jones CA,Nait-Oumesmar B,Zhao C,Huang JK,ffrench-Constant C,Franklin RJ
Mon Dec 07 00:00:00 EST 2015
TGF-β1, GDF-5, and BMP-2 stimulation induces chondrogenesis in expanded human articular chondrocytes and marrow-derived stromal cells.
Stem cells (Dayton, Ohio)
Murphy MK,Huey DJ,Hu JC,Athanasiou KA
Sun Mar 01 00:00:00 EST 2015
CXCL10 triggers early microglial activation in the cuprizone model.
Journal of immunology (Baltimore, Md. : 1950)
Clarner T,Janssen K,Nellessen L,Stangel M,Skripuletz T,Krauspe B,Hess FM,Denecke B,Beutner C,Linnartz-Gerlach B,Neumann H,Vallières L,Amor S,Ohl K,Tenbrock K,Beyer C,Kipp M
Wed Apr 01 00:00:00 EDT 2015
Dysfunction of platelet-derived growth factor receptor α (PDGFRα) represses the production of oligodendrocytes from arylsulfatase A-deficient multipotential neural precursor cells.
The Journal of biological chemistry
Pituch KC,Moyano AL,Lopez-Rosas A,Marottoli FM,Li G,Hu C,van Breemen R,Månsson JE,Givogri MI
Fri Mar 13 00:00:00 EDT 2015
Optimizing culture medium composition to improve oligodendrocyte progenitor cell yields in vitro from subventricular zone-derived neural progenitor cell neurospheres.
PloS one
Franco PG,Pasquini JM,Silvestroff L
100-13A was used in Cell Culture to study cell proliferation and OPC yield using Subventricular Zone-derived NSC/NPC primary cultures from newborn mice and studying the effects of different growth factor combinations on the. The Platelet Derived Growth Factor-AA and BB homodimers had a positive and significant impact on OPC generation. The OPC generated by this protocol were able to mature into Myelin Basic Protein-expressing cells, thus proposing an optimized in vitro method for increasing OPC.
Thu Mar 31 00:00:00 EDT 2016
Early treatment of minocycline alleviates white matter and cognitive impairments after chronic cerebral hypoperfusion.
Scientific reports
Ma J,Zhang J,Hou WW,Wu XH,Liao RJ,Chen Y,Wang Z,Zhang XN,Zhang LS,Zhou YD,Chen Z,Hu WW
Wed Jul 15 00:00:00 EDT 2015
EphB3 receptors function as dependence receptors to mediate oligodendrocyte cell death following contusive spinal cord injury.
Cell death & disease
Tsenkina Y,Ricard J,Runko E,Quiala-Acosta MM,Mier J,Liebl DJ
Thu Oct 15 00:00:00 EDT 2015
Human glial chimeric mice reveal astrocytic dependence of JC virus infection.
The Journal of clinical investigation
Kondo Y,Windrem MS,Zou L,Chandler-Militello D,Schanz SJ,Auvergne RM,Betstadt SJ,Harrington AR,Johnson M,Kazarov A,Gorelik L,Goldman SA
Mon Dec 01 00:00:00 EST 2014
Transcription factor induction of human oligodendrocyte progenitor fate and differentiation.
Proceedings of the National Academy of Sciences of the United States of America
Wang J,Pol SU,Haberman AK,Wang C,O'Bara MA,Sim FJ
Tue Jul 15 00:00:00 EDT 2014
Hominoid-specific enzyme GLUD2 promotes growth of IDH1R132H glioma.
Proceedings of the National Academy of Sciences of the United States of America
Chen R,Nishimura MC,Kharbanda S,Peale F,Deng Y,Daemen A,Forrest WF,Kwong M,Hedehus M,Hatzivassiliou G,Friedman LS,Phillips HS
Tue Sep 30 00:00:00 EDT 2014
Transformation of quiescent adult oligodendrocyte precursor cells into malignant glioma through a multistep reactivation process.
Proceedings of the National Academy of Sciences of the United States of America
Galvao RP,Kasina A,McNeill RS,Harbin JE,Foreman O,Verhaak RG,Nishiyama A,Miller CR,Zong H
Tue Oct 07 00:00:00 EDT 2014
Vasoprotective effect of PDGF-CC mediated by HMOX1 rescues retinal degeneration.
Proceedings of the National Academy of Sciences of the United States of America
He C,Zhao C,Kumar A,Lee C,Chen M,Huang L,Wang J,Ren X,Jiang Y,Chen W,Wang B,Gao Z,Zhong Z,Huang Z,Zhang F,Huang B,Ding H,Ju R,Tang Z,Liu Y,Cao Y,Li X,Liu X
Tue Oct 14 00:00:00 EDT 2014
Interaction of mTOR and Erk1/2 signaling to regulate oligodendrocyte differentiation.
Glia
Dai J,Bercury KK,Macklin WB
100-13A was used in Cell Culture to clarify the interactions between the Akt, mTOR, and Erk 1/2 major signaling pathways and understand more specifically the crosstalk between them.
Mon Dec 01 00:00:00 EST 2014
Heparin-binding domain of fibrin(ogen) binds growth factors and promotes tissue repair when incorporated within a synthetic matrix.
Proceedings of the National Academy of Sciences of the United States of America
Martino MM,Briquez PS,Ranga A,Lutolf MP,Hubbell JA
Tue Mar 19 00:00:00 EDT 2013
Identification of Tmem10 as a novel late-stage oligodendrocytes marker for detecting hypomyelination.
International journal of biological sciences
Jiang W,Yang W,Yang W,Zhang J,Pang D,Gan L,Luo L,Fan Y,Liu Y,Chen M
100-13A was used in Cell Culture to investigate Tmem10 in central nervous system to detect hypomyelination.
Fri Aug 22 00:00:00 EDT 2014
FAS-dependent cell death in α-synuclein transgenic oligodendrocyte models of multiple system atrophy.
PloS one
Kragh CL,Fillon G,Gysbers A,Hansen HD,Neumann M,Richter-Landsberg C,Haass C,Zalc B,Lubetzki C,Gai WP,Halliday GM,Kahle PJ,Jensen PH
Fri Jul 26 00:00:00 EDT 2013
Purification of oligodendrocyte precursor cells from rat cortices by immunopanning.
Cold Spring Harbor protocols
Dugas JC,Emery B
100-13A was used in Cell Culture to demonstrate how to purify oligodendrocyte precursor cells (OPCs) from postnatal rodent brains.
Thu Aug 01 00:00:00 EDT 2013
A rapid and reproducible assay for modeling myelination by oligodendrocytes using engineered nanofibers.
Nature protocols
Lee S,Chong SY,Tuck SJ,Corey JM,Chan JR
100-13A was used in In vitro experiments to describe protocols for the fabrication and preparation of nanofibers aligned on glass coverslips for the study of membrane wrapping by rodent oligodendrocytes.
Mon Apr 01 00:00:00 EDT 2013
A rapid and reproducible assay for modeling myelination by oligodendrocytes using engineered nanofibers.
Nature protocols
Lee S,Chong SY,Tuck SJ,Corey JM,Chan JR
100-13A was used in In vitro experiments to describe protocols for the fabrication and preparation of nanofibers aligned on glass coverslips for the study of membrane wrapping by rodent oligodendrocytes.
Mon Apr 01 00:00:00 EDT 2013
Spindle shaped human mesenchymal stem/stromal cells from amniotic fluid promote neovascularization.
PloS one
Roubelakis MG,Tsaknakis G,Pappa KI,Anagnou NP,Watt SM
Fri Sep 06 00:00:00 EDT 2013
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype.
Nature
Turcan S,Rohle D,Goenka A,Walsh LA,Fang F,Yilmaz E,Campos C,Fabius AW,Lu C,Ward PS,Thompson CB,Kaufman A,Guryanova O,Levine R,Heguy A,Viale A,Morris LG,Huse JT,Mellinghoff IK,Chan TA
Wed Feb 15 00:00:00 EST 2012
A culture system to study oligodendrocyte myelination processes using engineered nanofibers.
Nature methods
Lee S,Leach MK,Redmond SA,Chong SY,Mellon SH,Tuck SJ,Feng ZQ,Corey JM,Chan JR
Sat Sep 01 00:00:00 EDT 2012
Valproic acid confers functional pluripotency to human amniotic fluid stem cells in a transgene-free approach.
Molecular therapy : the journal of the American Society of Gene Therapy
Moschidou D,Mukherjee S,Blundell MP,Drews K,Jones GN,Abdulrazzak H,Nowakowska B,Phoolchund A,Lay K,Ramasamy TS,Cananzi M,Nettersheim D,Sullivan M,Frost J,Moore G,Vermeesch JR,Fisk NM,Thrasher AJ,Atala A,Adjaye J,Schorle H,De Coppi P,Guillot PV
Mon Oct 01 00:00:00 EDT 2012
Mesenchymal stem cells induced to secrete neurotrophic factors attenuate quinolinic acid toxicity: a potential therapy for Huntington's disease.
Experimental neurology
Sadan O,Shemesh N,Barzilay R,Dadon-Nahum M,Blumenfeld-Katzir T,Assaf Y,Yeshurun M,Djaldetti R,Cohen Y,Melamed E,Offen D
Sun Apr 01 00:00:00 EDT 2012
Human embryonic stem cell-derived oligodendrocyte progenitors aid in functional recovery of sensory pathways following contusive spinal cord injury.
PloS one
All AH,Bazley FA,Gupta S,Pashai N,Hu C,Pourmorteza A,Kerr C
Thu Mar 28 00:00:00 EDT 2013
Efficient derivation of multipotent neural stem/progenitor cells from non-human primate embryonic stem cells.
PloS one
Shimada H,Okada Y,Ibata K,Ebise H,Ota S,Tomioka I,Nomura T,Maeda T,Kohda K,Yuzaki M,Sasaki E,Nakamura M,Okano H
Mon May 06 00:00:00 EDT 2013
Interaction of inflammation and hyperoxia in a rat model of neonatal white matter damage.
PloS one
Brehmer F,Bendix I,Prager S,van de Looij Y,Reinboth BS,Zimmermanns J,Schlager GW,Brait D,Sifringer M,Endesfelder S,Sizonenko S,Mallard C,Bührer C,Felderhoff-Mueser U,Gerstner B
Thu May 09 00:00:00 EDT 2013
Loss of protein-tyrosine phosphatase α (PTPα) increases proliferation and delays maturation of oligodendrocyte progenitor cells.
The Journal of biological chemistry
Wang PS,Wang J,Zheng Y,Pallen CJ
Fri Apr 06 00:00:00 EDT 2012
PDGF induced microRNA alterations in cancer cells.
Nucleic acids research
Shao M,Rossi S,Chelladurai B,Shimizu M,Ntukogu O,Ivan M,Calin GA,Matei D
Sun May 01 00:00:00 EDT 2011
The PI3K-Akt pathway inhibits senescence and promotes self-renewal of human skin-derived precursors in vitro.
Aging cell
Liu S,Liu S,Wang X,Zhou J,Cao Y,Wang F,Duan E
Mon Aug 01 00:00:00 EDT 2011
Phosphatase and tensin homolog regulates the pluripotent state and lineage fate choice in human embryonic stem cells.
Stem cells (Dayton, Ohio)
Alva JA,Lee GE,Escobar EE,Pyle AD
Thu Dec 01 00:00:00 EST 2011
Schwann-like cell differentiation from rat bone marrow stem cells.
Archives of medical science : AMS
Kashani IR,Golipoor Z,Akbari M,Mahmoudi R,Azari S,Shirazi R,Bayat M,Ghasemi S
Tue Feb 01 00:00:00 EST 2011
Human glial-restricted progenitor transplantation into cervical spinal cord of the SOD1 mouse model of ALS.
PloS one
Lepore AC,O'Donnell J,Kim AS,Williams T,Tuteja A,Rao MS,Kelley LL,Campanelli JT,Maragakis NJ
Mon Feb 13 00:00:00 EST 2012
Role of palladin phosphorylation by extracellular signal-regulated kinase in cell migration.
PloS one
Asano E,Maeda M,Hasegawa H,Ito S,Hyodo T,Yuan H,Takahashi M,Hamaguchi M,Senga T
Mon May 21 00:00:00 EDT 2012
Role of palladin phosphorylation by extracellular signal-regulated kinase in cell migration.
PloS one
Asano E,Maeda M,Hasegawa H,Ito S,Hyodo T,Yuan H,Takahashi M,Hamaguchi M,Senga T
Mon May 21 00:00:00 EDT 2012
Synaptically-competent neurons derived from canine embryonic stem cells by lineage selection with EGF and Noggin.
PloS one
Wilcox JT,Lai JK,Semple E,Brisson BA,Gartley C,Armstrong JN,Betts DH
Mon Sep 12 00:00:00 EDT 2011
Gas6 increases myelination by oligodendrocytes and its deficiency delays recovery following cuprizone-induced demyelination.
PloS one
Binder MD,Xiao J,Kemper D,Ma GZ,Murray SS,Kilpatrick TJ
Thu Mar 10 00:00:00 EST 2011
L1TD1 is a marker for undifferentiated human embryonic stem cells.
PloS one
Wong RC,Ibrahim A,Fong H,Thompson N,Lock LF,Donovan PJ
Fri Apr 29 00:00:00 EDT 2011
Cardiac mast cells cause atrial fibrillation through PDGF-A-mediated fibrosis in pressure-overloaded mouse hearts.
The Journal of clinical investigation
Liao CH,Akazawa H,Tamagawa M,Ito K,Yasuda N,Kudo Y,Yamamoto R,Ozasa Y,Fujimoto M,Wang P,Nakauchi H,Nakaya H,Komuro I
Fri Jan 01 00:00:00 EST 2010
Esophageal cancer-related gene 4 is a secreted inducer of cell senescence expressed by aged CNS precursor cells.
Proceedings of the National Academy of Sciences of the United States of America
Kujuro Y,Suzuki N,Kondo T
Tue May 04 00:00:00 EDT 2010
MicroRNA expression profiling of oligodendrocyte differentiation from human embryonic stem cells.
PloS one
Letzen BS,Liu C,Thakor NV,Gearhart JD,All AH,Kerr CL
Wed May 05 00:00:00 EDT 2010
Platelet-derived growth factor differentially regulates the expression and post-translational modification of versican by arterial smooth muscle cells through distinct protein kinase C and extracellular signal-regulated kinase pathways.
The Journal of biological chemistry
Cardoso LE,Little PJ,Ballinger ML,Chan CK,Braun KR,Potter-Perigo S,Bornfeldt KE,Kinsella MG,Wight TN
Fri Mar 05 00:00:00 EST 2010
Subcellular localization of Mayven following expression of wild type and mutant EGFP tagged cDNAs.
BMC neuroscience
Montague P,Kennedy PG,Barnett SC
Wed May 26 00:00:00 EDT 2010
Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelination.
Cell
Emery B,Agalliu D,Cahoy JD,Watkins TA,Dugas JC,Mulinyawe SB,Ibrahim A,Ligon KL,Rowitch DH,Barres BA
Fri Jul 10 00:00:00 EDT 2009
p57kip2 is dynamically regulated in experimental autoimmune encephalomyelitis and interferes with oligodendroglial maturation.
Proceedings of the National Academy of Sciences of the United States of America
Kremer D,Heinen A,Jadasz J,Göttle P,Zimmermann K,Zickler P,Jander S,Hartung HP,Küry P
Tue Jun 02 00:00:00 EDT 2009
The transcription of FOXO genes is stimulated by FOXO3 and repressed by growth factors.
The Journal of biological chemistry
Essaghir A,Dif N,Marbehant CY,Coffer PJ,Demoulin JB
Fri Apr 17 00:00:00 EDT 2009
Protein-tyrosine phosphatase alpha acts as an upstream regulator of Fyn signaling to promote oligodendrocyte differentiation and myelination.
The Journal of biological chemistry
Wang PS,Wang J,Xiao ZC,Pallen CJ
Fri Nov 27 00:00:00 EST 2009
Growth factors outside of the platelet-derived growth factor (PDGF) family employ reactive oxygen species/Src family kinases to activate PDGF receptor alpha and thereby promote proliferation and survival of cells.
The Journal of biological chemistry
Lei H,Kazlauskas A
Fri Mar 06 00:00:00 EST 2009
Hyperoxia causes maturation-dependent cell death in the developing white matter.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Gerstner B,DeSilva TM,Genz K,Armstrong A,Brehmer F,Neve RL,Felderhoff-Mueser U,Volpe JJ,Rosenberg PA
100-13A was used in Tissue/organ culture to investigate the pathway of hyperoxia-induced oligodendrocyte death in rats.
Wed Jan 30 00:00:00 EST 2008
Molecular characterization of synovial sarcoma in children and adolescents: evidence of akt activation.
Translational oncology
Bozzi F,Ferrari A,Negri T,Conca E,Luca da R,Losa M,Casieri P,Orsenigo M,Lampis A,Meazza C,Casanova M,Pierotti MA,Tamborini E,Pilotti S
100-13A was used in Cell Culture to suggest that therapeutic strategies including specific inhibitors of the phosphatidylinositol 3-kinase/Akt pathway might be exploited in SS.
Tue Jul 01 00:00:00 EDT 2008
Essential roles of sphingosine-1-phosphate and platelet-derived growth factor in the maintenance of human embryonic stem cells.
Stem cells (Dayton, Ohio)
Pébay A,Wong RC,Pitson SM,Wolvetang EJ,Peh GS,Filipczyk A,Koh KL,Tellis I,Nguyen LT,Pera MF
Fri Mar 17 00:00:00 EST 2006
SB-431542 and Gleevec inhibit transforming growth factor-beta-induced proliferation of human osteosarcoma cells.
Cancer research
Matsuyama S,Iwadate M,Kondo M,Saitoh M,Hanyu A,Shimizu K,Aburatani H,Mishima HK,Imamura T,Miyazono K,Miyazawa K
Sat Nov 15 00:00:00 EST 2003
The Egr-1 gene is induced by epidermal growth factor in ECV304 cells and primary endothelial cells.
American journal of physiology. Cell physiology
Tsai JC,Liu L,Guan J,Aird WC
Wed Nov 01 00:00:00 EST 2000
The Egr-1 gene is induced by epidermal growth factor in ECV304 cells and primary endothelial cells.
American journal of physiology. Cell physiology
Tsai JC,Liu L,Guan J,Aird WC
Wed Nov 01 00:00:00 EST 2000
Cyclic AMP elevation is sufficient to promote the survival of spinal motor neurons in vitro.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Hanson MG,Shen S,Wiemelt AP,McMorris FA,Barres BA
Tue Sep 15 00:00:00 EDT 1998
