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Product Details
RP-43087
Product Specifications
Species
Human
Molecular weight
72 kDa
Class
Native
Type
Protein
Activity
Specific Activity = 6.7 U/mg; determined that 1 unit equals the prothrombin activity in 1 mL of normal human plasma.
Conjugate
Form
Liquid
Concentration
8 mg/mL
Purification
purified
Storage buffer
50% water with 50% glycerol
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
RP-43087 contains native human Prothrombin protein.
RP-43087 may be used as a positive control in many immunological assays.
The product is of human blood/plasma origin. Although the starting material was tested prior to initiation of the manufacturing process, and was found negative or nonreactive for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore and anti-HTLV I & II, extreme caution should be used when handling this material as there is a margin of error in all tests.
This product is to be used for IN VITRO research purposes only, and is not intended for clinical or diagnostic use!
Target Information
Prothrombin or Coagulation factor II, is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Coagulation factor II; coagulation factor II (thrombin); prepro-coagulation factor II; Prothrombin; prothrombin B-chain; serine protease
Gene Aliases: F2; PT; RPRGL2; THPH1
UniProt ID: (Human) P00734
Entrez Gene ID: (Human) 2147
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