Product References
Targeting a Tumor-Specific Epitope on Podocalyxin Increases Survival in Human Tumor Preclinical Models.
Frontiers in oncology
Canals Hernaez D,Hughes MR,Li Y,Mainero Rocca I,Dean P,Brassard J,Bell EM,Samudio I,Mes-Masson AM,Narimatsu Y,Clausen H,Blixt O,Roskelley CD,McNagny KM
AF-300-07 was used in Sample Preparation (FC/FACS) to use an array of glycosylation defective cell lines to define the PODO447 reactive epitope and reveal it as an O-linked core 1 glycan presented in the context of the Podxl peptide backbone.
Sat Jul 16 00:00:00 EDT 2022
Reactivation of a developmentally silenced embryonic globin gene.
Nature communications
King AJ,Songdej D,Downes DJ,Beagrie RA,Liu S,Buckley M,Hua P,Suciu MC,Marieke Oudelaar A,Hanssen LLP,Jeziorska D,Roberts N,Carpenter SJ,Francis H,Telenius J,Olijnik AA,Sharpe JA,Sloane-Stanley J,Eglinton J,Kassouf MT,Orkin SH,Pennacchio LA,Davies JOJ,Hughes JR,Higgs DR,Babbs C
Wed Jul 21 00:00:00 EDT 2021
Notch3 contributes to T-cell leukemia growth via regulation of the unfolded protein response.
Oncogenesis
Giuli MV,Diluvio G,Giuliani E,Franciosa G,Di Magno L,Pignataro MG,Tottone L,Nicoletti C,Besharat ZM,Peruzzi G,Pelullo M,Palermo R,Canettieri G,Talora C,d'Amati G,Bellavia D,Screpanti I,Checquolo S
Sun Oct 18 00:00:00 EDT 2020
NTAL is associated with treatment outcome, cell proliferation and differentiation in acute promyelocytic leukemia.
Scientific reports
Thomé CH,Ferreira GA,Pereira-Martins DA,Dos Santos GA,Ortiz CA,de Souza LEB,Sobral LM,Silva CLA,Scheucher PS,Gil CD,Leopoldino AM,Silveira DRA,Coelho-Silva JL,Traina F,Koury LC,Melo RAM,Bittencourt R,Pagnano K,Pasquini R,Nunes EC,Fagundes EM,Gloria ABF,Kerbauy FR,Chauffaille ML,Keating A,Tallman MS,Ribeiro RC,Dillon R,Ganser A,Löwenberg B,Valk P,Lo-Coco F,Sanz MA,Berliner N,Faça VM,Rego EM
Thu Jun 25 00:00:00 EDT 2020
Neutrophils Derived from Genetically Modified Human Induced Pluripotent Stem Cells Circulate and Phagocytose Bacteria In Vivo.
Stem cells translational medicine
Trump LR,Nayak RC,Singh AK,Emberesh S,Wellendorf AM,Lutzko CM,Cancelas JA
Sat Jun 01 00:00:00 EDT 2019
Gene correction for SCID-X1 in long-term hematopoietic stem cells.
Nature communications
Pavel-Dinu M,Wiebking V,Dejene BT,Srifa W,Mantri S,Nicolas CE,Lee C,Bao G,Kildebeck EJ,Punjya N,Sindhu C,Inlay MA,Saxena N,DeRavin SS,Malech H,Roncarolo MG,Weinberg KI,Porteus MH
Tue Apr 09 00:00:00 EDT 2019
Functionalization of Brain Region-specific Spheroids with Isogenic Microglia-like Cells.
Scientific reports
Song L,Yuan X,Jones Z,Vied C,Miao Y,Marzano M,Hua T,Sang QA,Guan J,Ma T,Zhou Y,Li Y
Tue Jul 30 00:00:00 EDT 2019
TAF1 plays a critical role in AML1-ETO driven leukemogenesis.
Nature communications
Xu Y,Man N,Karl D,Martinez C,Liu F,Sun J,Martinez CJ,Martin GM,Beckedorff F,Lai F,Yue J,Roisman A,Greenblatt S,Duffort S,Wang L,Sun X,Figueroa M,Shiekhattar R,Nimer S
Tue Oct 29 00:00:00 EDT 2019
Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia.
Nature communications
Minuesa G,Albanese SK,Xie W,Kazansky Y,Worroll D,Chow A,Schurer A,Park SM,Rotsides CZ,Taggart J,Rizzi A,Naden LN,Chou T,Gourkanti S,Cappel D,Passarelli MC,Fairchild L,Adura C,Glickman JF,Schulman J,Famulare C,Patel M,Eibl JK,Ross GM,Bhattacharya S,Tan DS,Leslie CS,Beuming T,Patel DJ,Goldgur Y,Chodera JD,Kharas MG
Wed Jun 19 00:00:00 EDT 2019
Targeting specificity of APOBEC-based cytosine base editor in human iPSCs determined by whole genome sequencing.
Nature communications
McGrath E,Shin H,Zhang L,Phue JN,Wu WW,Shen RF,Jang YY,Revollo J,Ye Z
Mon Nov 25 00:00:00 EST 2019
Ex Vivo Expansion of CD34+ CD90+ CD49f+ Hematopoietic Stem and Progenitor Cells from Non-Enriched Umbilical Cord Blood with Azole Compounds.
Stem cells translational medicine
Bari S,Zhong Q,Fan X,Poon Z,Lim AST,Lim TH,Dighe N,Li S,Chiu GNC,Chai CLL,Hwang WYK
Tue May 01 00:00:00 EDT 2018
Gene therapy for Wiskott-Aldrich syndrome in a severely affected adult.
Blood
Morris EC,Fox T,Chakraverty R,Tendeiro R,Snell K,Rivat C,Grace S,Gilmour K,Workman S,Buckland K,Butler K,Chee R,Salama AD,Ibrahim H,Hara H,Duret C,Mavilio F,Male F,Bushman FD,Galy A,Burns SO,Gaspar HB,Thrasher AJ
Thu Sep 14 00:00:00 EDT 2017
Engraftment and in vivo proliferation advantage of gene-corrected mobilized CD34+ cells from Fanconi anemia patients.
Blood
Río P,Navarro S,Guenechea G,Sánchez-Domínguez R,Lamana ML,Yañez R,Casado JA,Mehta PA,Pujol MR,Surrallés J,Charrier S,Galy A,Segovia JC,Díaz de Heredia C,Sevilla J,Bueren JA
Thu Sep 28 00:00:00 EDT 2017
Identification of novel genes and networks governing hematopoietic stem cell development.
EMBO reports
Han T,Yang CS,Chang KY,Zhang D,Imam FB,Rana TM
Thu Dec 01 00:00:00 EST 2016
Generation and Characterization of Patient-Specific Induced Pluripotent Stem Cell for Disease Modeling.
Methods in molecular biology (Clifton, N.J.)
Sivapatham R,Zeng X
AF-300-07 was used in Cell Culture to describe the generation and characterization of iPSC from blood or fibroblast on a routine base and focus on the integration-free methodologies.
Thu Aug 18 00:00:00 EDT 2016
A Newly Defined and Xeno-Free Culture Medium Supports Every-Other-Day Medium Replacement in the Generation and Long-Term Cultivation of Human Pluripotent Stem Cells.
PloS one
Ahmadian Baghbaderani B,Tian X,Scotty Cadet J,Shah K,Walde A,Tran H,Kovarcik DP,Clarke D,Fellner T
AF-300-07 was used in Cell Culture to show that the medium plays an integral role in establishing a cGMP-compliant process for the manufacturing of hiPSCs that can be used for generation of clinically relevant cell types for cell replacement therapy applications.
Fri Aug 04 00:00:00 EDT 2017
Role of SOX17 in hematopoietic development from human embryonic stem cells.
Blood
Nakajima-Takagi Y,Osawa M,Oshima M,Takagi H,Miyagi S,Endoh M,Endo TA,Takayama N,Eto K,Toyoda T,Koseki H,Nakauchi H,Iwama A
Thu Jan 17 00:00:00 EST 2013
Genomic impact of transient low-dose decitabine treatment on primary AML cells.
Blood
Klco JM,Spencer DH,Lamprecht TL,Sarkaria SM,Wylie T,Magrini V,Hundal J,Walker J,Varghese N,Erdmann-Gilmore P,Lichti CF,Meyer MR,Townsend RR,Wilson RK,Mardis ER,Ley TJ
Thu Feb 28 00:00:00 EST 2013
TNF-α has tropic rather than apoptotic activity in human hematopoietic progenitors: involvement of TNF receptor-1 and caspase-8.
Stem cells (Dayton, Ohio)
Mizrahi K,Stein J,Yaniv I,Kaplan O,Askenasy N
Tue Jan 01 00:00:00 EST 2013
Expression of stem cell factor in gastrointestinal stromal tumors: Implications for proliferation and imatinib resistance.
Oncology letters
Hou XW,Bai CG,Liu XH,Qiu C,Huang L,Xu JJ,Ma DL
Fri Feb 01 00:00:00 EST 2013
IGF-1 promotes the development and cytotoxic activity of human NK cells.
Nature communications
Ni F,Sun R,Fu B,Wang F,Guo C,Tian Z,Wei H
Thu Jun 20 00:00:00 EDT 2013
Coupling endonucleases with DNA end-processing enzymes to drive gene disruption.
Nature methods
Certo MT,Gwiazda KS,Kuhar R,Sather B,Curinga G,Mandt T,Brault M,Lambert AR,Baxter SK,Jacoby K,Ryu BY,Kiem HP,Gouble A,Paques F,Rawlings DJ,Scharenberg AM
Mon Oct 01 00:00:00 EDT 2012
FANCL ubiquitinates β-catenin and enhances its nuclear function.
Blood
Dao KH,Rotelli MD,Petersen CL,Kaech S,Nelson WD,Yates JE,Hanlon Newell AE,Olson SB,Druker BJ,Bagby GC
Thu Jul 12 00:00:00 EDT 2012
RNAi screen identifies MAPK14 as a druggable suppressor of human hematopoietic stem cell expansion.
Blood
Baudet A,Karlsson C,Safaee Talkhoncheh M,Galeev R,Magnusson M,Larsson J
Thu Jun 28 00:00:00 EDT 2012
APELIN promotes hematopoiesis from human embryonic stem cells.
Blood
Yu QC,Hirst CE,Costa M,Ng ES,Schiesser JV,Gertow K,Stanley EG,Elefanty AG
Thu Jun 28 00:00:00 EDT 2012
Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models.
The Journal of experimental medicine
Thiollier C,Lopez CK,Gerby B,Ignacimouttou C,Poglio S,Duffourd Y,Guégan J,Rivera-Munoz P,Bluteau O,Mabialah V,Diop M,Wen Q,Petit A,Bauchet AL,Reinhardt D,Bornhauser B,Gautheret D,Lecluse Y,Landman-Parker J,Radford I,Vainchenker W,Dastugue N,de Botton S,Dessen P,Bourquin JP,Crispino JD,Ballerini P,Bernard OA,Pflumio F,Mercher T
Mon Oct 22 00:00:00 EDT 2012
Identification of Axl as a downstream effector of TGF-β1 during Langerhans cell differentiation and epidermal homeostasis.
The Journal of experimental medicine
Bauer T,Zagórska A,Jurkin J,Yasmin N,Köffel R,Richter S,Gesslbauer B,Lemke G,Strobl H
Mon Oct 22 00:00:00 EDT 2012
Perturbation of fetal liver hematopoietic stem and progenitor cell development by trisomy 21.
Proceedings of the National Academy of Sciences of the United States of America
Roy A,Cowan G,Mead AJ,Filippi S,Bohn G,Chaidos A,Tunstall O,Chan JK,Choolani M,Bennett P,Kumar S,Atkinson D,Wyatt-Ashmead J,Hu M,Stumpf MP,Goudevenou K,O'Connor D,Chou ST,Weiss MJ,Karadimitris A,Jacobsen SE,Vyas P,Roberts I
Tue Oct 23 00:00:00 EDT 2012
GILZ inhibits the mTORC2/AKT pathway in BCR-ABL(+) cells.
Oncogene
Joha S,Nugues AL,Hétuin D,Berthon C,Dezitter X,Dauphin V,Mahon FX,Roche-Lestienne C,Preudhomme C,Quesnel B,Idziorek T
Thu Mar 15 00:00:00 EDT 2012
Intercellular cytosolic transfer correlates with mesenchymal stromal cell rescue of umbilical cord blood cell viability during ex vivo expansion.
Cytotherapy
Chu PP,Bari S,Fan X,Gay FP,Ang JM,Chiu GN,Lim SK,Hwang WY
Mon Oct 01 00:00:00 EDT 2012
Characterization and function of histamine receptors in human bone marrow stromal cells.
Stem cells (Dayton, Ohio)
Nemeth K,Wilson T,Rada B,Parmelee A,Mayer B,Buzas E,Falus A,Key S,Masszi T,Karpati S,Mezey E
Wed Feb 01 00:00:00 EST 2012
Human T-lymphoid progenitors generated in a feeder-cell-free Delta-like-4 culture system promote T-cell reconstitution in NOD/SCID/γc(-/-) mice.
Stem cells (Dayton, Ohio)
Reimann C,Six E,Dal-Cortivo L,Schiavo A,Appourchaux K,Lagresle-Peyrou C,de Chappedelaine C,Ternaux B,Coulombel L,Beldjord K,Cavazzana-Calvo M,Andre-Schmutz I
Wed Aug 01 00:00:00 EDT 2012
Adipocyte-derived soluble factor(s) inhibits early stages of B lymphopoiesis.
Journal of immunology (Baltimore, Md. : 1950)
Bilwani FA,Knight KL
Thu Nov 01 00:00:00 EDT 2012
Adipocyte-derived soluble factor(s) inhibits early stages of B lymphopoiesis.
Journal of immunology (Baltimore, Md. : 1950)
Bilwani FA,Knight KL
Thu Nov 01 00:00:00 EDT 2012
Adipocyte-derived soluble factor(s) inhibits early stages of B lymphopoiesis.
Journal of immunology (Baltimore, Md. : 1950)
Bilwani FA,Knight KL
Thu Nov 01 00:00:00 EDT 2012
The aryl hydrocarbon receptor modulates acute and late mast cell responses.
Journal of immunology (Baltimore, Md. : 1950)
Sibilano R,Frossi B,Calvaruso M,Danelli L,Betto E,Dall'Agnese A,Tripodo C,Colombo MP,Pucillo CE,Gri G
Sun Jul 01 00:00:00 EDT 2012
Generation of virus-free induced pluripotent stem cell clones on a synthetic matrix via a single cell subcloning in the naïve state.
PloS one
Nishishita N,Shikamura M,Takenaka C,Takada N,Fusaki N,Kawamata S
Thu Dec 13 00:00:00 EST 2012
Human umbilical cord blood-derived CD34+ cells reverse osteoporosis in NOD/SCID mice by altering osteoblastic and osteoclastic activities.
PloS one
Aggarwal R,Lu J,Kanji S,Joseph M,Das M,Noble GJ,McMichael BK,Agarwal S,Hart RT,Sun Z,Lee BS,Rosol TJ,Jackson R,Mao HQ,Pompili VJ,Das H
Wed Dec 12 00:00:00 EST 2012
Very small embryonic-like stem cells purified from umbilical cord blood lack stem cell characteristics.
PloS one
Danova-Alt R,Heider A,Egger D,Cross M,Alt R
Tue Aug 07 00:00:00 EDT 2012
Residual expression of the reprogramming factors prevents differentiation of iPSC generated from human fibroblasts and cord blood CD34+ progenitors.
PloS one
Ramos-Mejía V,Montes R,Bueno C,Ayllón V,Real PJ,Rodríguez R,Menendez P
Mon Aug 27 00:00:00 EDT 2012
Human embryonic stem cells differentiated to lung lineage-specific cells ameliorate pulmonary fibrosis in a xenograft transplant mouse model.
PloS one
Banerjee ER,Laflamme MA,Papayannopoulou T,Kahn M,Murry CE,Henderson WR
Fri Aug 03 00:00:00 EDT 2012
Inhibition of Mammalian target of rapamycin in human acute myeloid leukemia cells has diverse effects that depend on the environmental in vitro stress.
Bone marrow research
Ryningen A,Reikvam H,Nepstad I,Paulsen Rye K,Bruserud O
Mon Oct 22 00:00:00 EDT 2012
Acetylation of histone deacetylase 1 regulates NuRD corepressor complex activity.
The Journal of biological chemistry
Yang T,Jian W,Luo Y,Fu X,Noguchi C,Bungert J,Huang S,Qiu Y
Fri Nov 23 00:00:00 EST 2012
Direct chromatin PCR (DC-PCR): hypotonic conditions allow differentiation of chromatin states during thermal cycling.
PloS one
Vatolin S,Khan SN,Reu FJ
Tue Mar 12 00:00:00 EDT 2013
Pharmacological inhibition of caspase and calpain proteases: a novel strategy to enhance the homing responses of cord blood HSPCs during expansion.
PloS one
Sangeetha VM,Kadekar D,Kale VP,Limaye LS
Mon May 14 00:00:00 EDT 2012
Suppression of homeobox transcription factor VentX promotes expansion of human hematopoietic stem/multipotent progenitor cells.
The Journal of biological chemistry
Gao H,Wu X,Sun Y,Zhou S,Silberstein LE,Zhu Z
Fri Aug 24 00:00:00 EDT 2012
Micro-RNA30c negatively regulates REDD1 expression in human hematopoietic and osteoblast cells after gamma-irradiation.
PloS one
Li XH,Ha CT,Fu D,Xiao M
Thu May 09 00:00:00 EDT 2013
Distinct regulation of c-myb gene expression by HoxA9, Meis1 and Pbx proteins in normal hematopoietic progenitors and transformed myeloid cells.
Blood cancer journal
Dassé E,Volpe G,Walton DS,Wilson N,Del Pozzo W,O'Neill LP,Slany RK,Frampton J,Dumon S
Fri Jun 01 00:00:00 EDT 2012
Anti-apoptotic BFL-1 is the major effector in activation-induced human mast cell survival.
PloS one
Ekoff M,Lyberg K,Krajewska M,Arvidsson M,Rak S,Reed JC,Harvima I,Nilsson G
Thu Dec 13 00:00:00 EST 2012
RNA sensors enable human mast cell anti-viral chemokine production and IFN-mediated protection in response to antibody-enhanced dengue virus infection.
PloS one
Brown MG,McAlpine SM,Huang YY,Haidl ID,Al-Afif A,Marshall JS,Anderson R
Mon Nov 05 00:00:00 EST 2012
Lentiviral transduction of CD34(+) cells induces genome-wide epigenetic modifications.
PloS one
Yamagata Y,Parietti V,Stockholm D,Corre G,Poinsignon C,Touleimat N,Delafoy D,Besse C,Tost J,Galy A,Paldi A
Wed Jul 24 00:00:00 EDT 2013
NKX2-5(eGFP/w) hESCs for isolation of human cardiac progenitors and cardiomyocytes.
Nature methods
Elliott DA,Braam SR,Koutsis K,Ng ES,Jenny R,Lagerqvist EL,Biben C,Hatzistavrou T,Hirst CE,Yu QC,Skelton RJ,Ward-van Oostwaard D,Lim SM,Khammy O,Li X,Hawes SM,Davis RP,Goulburn AL,Passier R,Prall OW,Haynes JM,Pouton CW,Kaye DM,Mummery CL,Elefanty AG,Stanley EG
Sun Oct 23 00:00:00 EDT 2011
Rho kinase regulates the survival and transformation of cells bearing oncogenic forms of KIT, FLT3, and BCR-ABL.
Cancer cell
Mali RS,Ramdas B,Ma P,Shi J,Munugalavadla V,Sims E,Wei L,Vemula S,Nabinger SC,Goodwin CB,Chan RJ,Traina F,Visconte V,Tiu RV,Lewis TA,Stern AM,Wen Q,Crispino JD,Boswell HS,Kapur R
Tue Sep 13 00:00:00 EDT 2011
BCR-ABL suppresses autophagy through ATF5-mediated regulation of mTOR transcription.
Blood
Sheng Z,Ma L,Sun JE,Zhu LJ,Green MR
Thu Sep 08 00:00:00 EDT 2011
Cytoskeletal remodeling mediated by WASp in dendritic cells is necessary for normal immune synapse formation and T-cell priming.
Blood
Bouma G,Mendoza-Naranjo A,Blundell MP,de Falco E,Parsley KL,Burns SO,Thrasher AJ
Thu Sep 01 00:00:00 EDT 2011
Production of the plasma-cell survival factor a proliferation-inducing ligand (APRIL) peaks in myeloid precursor cells from human bone marrow.
Blood
Matthes T,Dunand-Sauthier I,Santiago-Raber ML,Krause KH,Donze O,Passweg J,McKee T,Huard B
Thu Aug 18 00:00:00 EDT 2011
Glycogen synthase kinase-3β is a prosurvival signal for the maintenance of human mast cell homeostasis.
Journal of immunology (Baltimore, Md. : 1950)
Rådinger M,Smrž D,Metcalfe DD,Gilfillan AM
Thu Dec 01 00:00:00 EST 2011
Specific cellular signal-transduction responses to in vivo combination therapy with ATRA, valproic acid and theophylline in acute myeloid leukemia.
Blood cancer journal
Skavland J,Jørgensen KM,Hadziavdic K,Hovland R,Jonassen I,Bruserud O,Gjertsen BT
Tue Feb 01 00:00:00 EST 2011
Amino-terminal enhancer of split (AES) interacts with the oncoprotein NUP98-HOXA9 and enhances its transforming ability.
The Journal of biological chemistry
Sarma NJ,Yaseen NR
Fri Nov 11 00:00:00 EST 2011
Congenital dyserythropoietic anemia type II: molecular analysis and expression of the SEC23B gene.
Orphanet journal of rare diseases
Punzo F,Bertoli-Avella AM,Scianguetta S,Della Ragione F,Casale M,Ronzoni L,Cappellini MD,Forni G,Oostra BA,Perrotta S
Fri Dec 30 00:00:00 EST 2011
Human fetal liver: an in vitro model of erythropoiesis.
Stem cells international
Pourcher G,Mazurier C,King YY,Giarratana MC,Kobari L,Boehm D,Douay L,Lapillonne H
Thu Nov 10 00:00:00 EST 2011
