Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This peptide corresponds to 18 amino acid peptide near the center of human SGSM2.
PEP-1481 can be used as a blocking peptide with polyclonal antibody PA5-34439.
Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM2 is a Rab9A effector that activates GTP hydrolysis by Rab32 and Rab33B proteins.
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Protein Aliases: RUN and TBC1 domain containing 1; RUN and TBC1 domain-containing protein 1; Small G protein signaling modulator 2; small G protein signaling modulator 2 protein
Gene Aliases: KIAA0397; RUTBC1; SGSM2
UniProt ID: (Human) O43147
Entrez Gene ID: (Human) 9905
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