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This peptide corresponds to 17 amino acids near the carboxy terminus of human SIRT6.
PEP-1081 can be used as a blocking peptide with polyclonal antibody PA5-20967.
Sirtuins regulate epigenetic gene silencing. SIRT6 (Mono-ADP-ribosyltransferase sirtuin-6), a mouse Sir2 homolog, is a chromatin-associated nuclear ADP-ribosyltransferase protein. It appears to be involved in DNA repair and may also play a role in human aging.
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Protein Aliases: hSIRT6; NAD-dependent protein deacetylase sirtuin-6; NAD-dependent protein deacylase sirtuin-6; Protein mono-ADP-ribosyltransferase sirtuin-6; Regulatory protein SIR2 homolog 6; SIR2; SIR2 like 6; SIR2-like protein 6; sir2-related protein type 6; sirtuin type 6
Gene Aliases: SIR2L6; SIRT6
UniProt ID: (Human) Q8N6T7
Entrez Gene ID: (Human) 51548
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