Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This peptide corresponds to 17 amino acids near the amino terminus of human SYNGR2.
PEP-0991 can be used as a blocking peptide with polyclonal antibody PA5-20877.
Synaptogyrins comprise a family of tyrosine-phosphorylated membrane proteins with two neuronal (SYNGR1 and SYNGR3) and one ubiquitous (SYNGR2) members. SYNGR1 and -3 are synaptic vesicle proteins, residing in some cases on the same synaptic vesicle, and are thought to be involved in the regulation of neurotransmitter release. SYNGR2, by contrast, is absent from synaptic vesicles. The role and localization of a fourth synaptogyrin, SYNGR4, is unclear. SYNGR3 is predominantly expressed in brain and placenta. The exact function of SYNGR2 is unknown, but studies suggest that it may play a role in regulating membrane traffic in non-neuronal cells.
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Protein Aliases: Cellugyrin; MGC102914; Synaptogyrin-2
Gene Aliases: SYNGR2; UNQ352/PRO615
UniProt ID: (Human) O43760
Entrez Gene ID: (Human) 9144
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