Product References
Dysregulated overexpression of Sox9 induces fibroblast activation in pulmonary fibrosis.
JCI insight
Gajjala PR,Kasam RK,Soundararajan D,Sinner D,Huang SK,Jegga AG,Madala SK
100-16A was used in Cell Culture to conclude that Sox9 functions as a profibrotic transcription factor in activating fibroblasts, illustrating the potential utility of targeting Sox9 in IPF treatment.
Fri Oct 22 00:00:00 EDT 2021
Reciprocal priming between receptor tyrosine kinases at recycling endosomes orchestrates cellular signalling outputs.
The EMBO journal
Smith MP,Ferguson HR,Ferguson J,Zindy E,Kowalczyk KM,Kedward T,Bates C,Parsons J,Watson J,Chandler S,Fullwood P,Warwood S,Knight D,Clarke RB,Francavilla C
100-16A was used in Sample Preparation to study how signalling integration is regulated and whether the endocytic fate of single receptors controls signalling integration.
Thu Jul 15 00:00:00 EDT 2021
A new protocol for long-term culture of a specific subpopulation of liver cancer stem cells enriched by cell surface markers.
FEBS open bio
Zhang B,Wang HY,Wang DX,Zeng Q,Fan Z,Xi JF,Nan X,He LJ,Zhou JN,Pei XT,Yue W
Tue Sep 01 00:00:00 EDT 2020
Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites.
Cell
Lundby A,Franciosa G,Emdal KB,Refsgaard JC,Gnosa SP,Bekker-Jensen DB,Secher A,Maurya SR,Paul I,Mendez BL,Kelstrup CD,Francavilla C,Kveiborg M,Montoya G,Jensen LJ,Olsen JV
Thu Oct 03 00:00:00 EDT 2019
The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase.
Cell
Sanghvi VR,Leibold J,Mina M,Mohan P,Berishaj M,Li Z,Miele MM,Lailler N,Zhao C,de Stanchina E,Viale A,Akkari L,Lowe SW,Ciriello G,Hendrickson RC,Wendel HG
Thu Aug 08 00:00:00 EDT 2019
p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors.
Cancer cell
Carugo A,Minelli R,Sapio L,Soeung M,Carbone F,Robinson FS,Tepper J,Chen Z,Lovisa S,Svelto M,Amin S,Srinivasan S,Del Poggetto E,Loponte S,Puca F,Dey P,Malouf GG,Su X,Li L,Lopez-Terrada D,Rakheja D,Lazar AJ,Netto GJ,Rao P,Sgambato A,Maitra A,Tripathi DN,Walker CL,Karam JA,Heffernan TP,Viale A,Roberts CWM,Msaouel P,Tannir NM,Draetta GF,Genovese G
Mon Feb 11 00:00:00 EST 2019
The role of insulin in transdifferentiated hepatocyte proliferation and function in serum-free medium.
Journal of cellular and molecular medicine
Gu C,Li P,Liu W,Zhou Y,Tan WS
Sat Jun 01 00:00:00 EDT 2019
Activin Is Superior to BMP7 for Efficient Maintenance of Human iPSC-Derived Nephron Progenitors.
Stem cell reports
Tanigawa S,Naganuma H,Kaku Y,Era T,Sakuma T,Yamamoto T,Taguchi A,Nishinakamura R
Tue Aug 13 00:00:00 EDT 2019
cIAP1 regulates the EGFR/Snai2 axis in triple-negative breast cancer cells.
Cell death and differentiation
Majorini MT,Manenti G,Mano M,De Cecco L,Conti A,Pinciroli P,Fontanella E,Tagliabue E,Chiodoni C,Colombo MP,Delia D,Lecis D
Sat Dec 01 00:00:00 EST 2018
Ligand-activated epidermal growth factor receptor (EGFR) signaling governs endocytic trafficking of unliganded receptor monomers by non-canonical phosphorylation.
The Journal of biological chemistry
Tanaka T,Zhou Y,Ozawa T,Okizono R,Banba A,Yamamura T,Oga E,Muraguchi A,Sakurai H
Fri Feb 16 00:00:00 EST 2018
ADAM17/EGFR axis promotes transglutaminase-dependent skin barrier formation through phospholipase C γ1 and protein kinase C pathways.
Scientific reports
Wolf C,Qian Y,Brooke MA,Kelsell DP,Franzke CW
Thu Dec 22 00:00:00 EST 2016
Basal cells contribute to innate immunity of the airway epithelium through production of the antimicrobial protein RNase 7.
Journal of immunology (Baltimore, Md. : 1950)
Amatngalim GD,van Wijck Y,de Mooij-Eijk Y,Verhoosel RM,Harder J,Lekkerkerker AN,Janssen RA,Hiemstra PS
Wed Apr 01 00:00:00 EDT 2015
Network-Based Analysis of Nutraceuticals in Human Hepatocellular Carcinomas Reveals Mechanisms of Chemopreventive Action.
CPT: pharmacometrics & systems pharmacology
Michailidou M,Melas IN,Messinis DE,Klamt S,Alexopoulos LG,Kolisis FN,Loutrari H
Mon Jun 01 00:00:00 EDT 2015
Smooth muscle cells relay acute pulmonary inflammation via distinct ADAM17/ErbB axes.
Journal of immunology (Baltimore, Md. : 1950)
Dreymueller D,Martin C,Schumacher J,Groth E,Boehm JK,Reiss LK,Uhlig S,Ludwig A
Wed Jan 15 00:00:00 EST 2014
Epidermal growth factor receptor (EGFR) signaling regulates epiphyseal cartilage development through β-catenin-dependent and -independent pathways.
The Journal of biological chemistry
Zhang X,Zhu J,Li Y,Lin T,Siclari VA,Chandra A,Candela EM,Koyama E,Enomoto-Iwamoto M,Qin L
Fri Nov 08 00:00:00 EST 2013
Epidermal growth factor receptor (EGFR) signaling regulates epiphyseal cartilage development through β-catenin-dependent and -independent pathways.
The Journal of biological chemistry
Zhang X,Zhu J,Li Y,Lin T,Siclari VA,Chandra A,Candela EM,Koyama E,Enomoto-Iwamoto M,Qin L
Fri Nov 08 00:00:00 EST 2013
cAMP response element-binding protein (CREB) and nuclear factor κB mediate the tamoxifen-induced up-regulation of glutamate transporter 1 (GLT-1) in rat astrocytes.
The Journal of biological chemistry
Karki P,Webb A,Smith K,Lee K,Son DS,Aschner M,Lee E
Fri Oct 04 00:00:00 EDT 2013
Carboxypeptidase-M is regulated by lipids and CSFs in macrophages and dendritic cells and expressed selectively in tissue granulomas and foam cells.
Laboratory investigation; a journal of technical methods and pathology
Tsakiris I,Torocsik D,Gyongyosi A,Dozsa A,Szatmari I,Szanto A,Soos G,Nemes Z,Igali L,Marton I,Takats Z,Nagy L,Dezso B
Thu Mar 01 00:00:00 EST 2012
Loss of runt-related transcription factor 3 expression leads hepatocellular carcinoma cells to escape apoptosis.
BMC cancer
Nakanishi Y,Shiraha H,Nishina S,Tanaka S,Matsubara M,Horiguchi S,Iwamuro M,Takaoka N,Uemura M,Kuwaki K,Hagihara H,Toshimori J,Ohnishi H,Takaki A,Nakamura S,Kobayashi Y,Nouso K,Yagi T,Yamamoto K
Tue Jan 04 00:00:00 EST 2011
IκB kinase β regulates epithelium migration during corneal wound healing.
PloS one
Chen L,Meng Q,Kao W,Xia Y
Mon Jan 17 00:00:00 EST 2011
High- and low-affinity epidermal growth factor receptor-ligand interactions activate distinct signaling pathways.
PloS one
Krall JA,Beyer EM,MacBeath G
Mon Jan 10 00:00:00 EST 2011
Fetal derived embryonic-like stem cells improve healing in a large animal flexor tendonitis model.
Stem cell research & therapy
Watts AE,Yeager AE,Kopyov OV,Nixon AJ
Thu Jan 27 00:00:00 EST 2011
Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice.
The Journal of experimental medicine
Chalaris A,Adam N,Sina C,Rosenstiel P,Lehmann-Koch J,Schirmacher P,Hartmann D,Cichy J,Gavrilova O,Schreiber S,Jostock T,Matthews V,Häsler R,Becker C,Neurath MF,Reiss K,Saftig P,Scheller J,Rose-John S
Mon Aug 02 00:00:00 EDT 2010
Tailored cancer immunotherapy using combinations of chemotherapy and a mixture of antibodies against EGF-receptor ligands.
Proceedings of the National Academy of Sciences of the United States of America
Lindzen M,Lavi S,Leitner O,Yarden Y
Tue Jul 13 00:00:00 EDT 2010
Injury is a major inducer of epidermal innate immune responses during wound healing.
The Journal of investigative dermatology
Roupé KM,Nybo M,Sjöbring U,Alberius P,Schmidtchen A,Sørensen OE
Thu Apr 01 00:00:00 EDT 2010
Antimicrobial activity of human prion protein is mediated by its N-terminal region.
PloS one
Pasupuleti M,Roupe M,Rydengård V,Surewicz K,Surewicz WK,Chalupka A,Malmsten M,Sörensen OE,Schmidtchen A
Wed Oct 07 00:00:00 EDT 2009
Mesenchymal cells from adult kidney support angiogenesis and differentiate into multiple interstitial cell types including erythropoietin-producing fibroblasts.
American journal of physiology. Renal physiology
Plotkin MD,Goligorsky MS
Sun Oct 01 00:00:00 EDT 2006
Inhibition of glioblastoma angiogenesis and invasion by combined treatments directed against vascular endothelial growth factor receptor-2, epidermal growth factor receptor, and vascular endothelial-cadherin.
Clinical cancer research : an official journal of the American Association for Cancer Research
Lamszus K,Brockmann MA,Eckerich C,Bohlen P,May C,Mangold U,Fillbrandt R,Westphal M
Fri Jul 01 00:00:00 EDT 2005
Dual mode of action of a human anti-epidermal growth factor receptor monoclonal antibody for cancer therapy.
Journal of immunology (Baltimore, Md. : 1950)
Bleeker WK,Lammerts van Bueren JJ,van Ojik HH,Gerritsen AF,Pluyter M,Houtkamp M,Halk E,Goldstein J,Schuurman J,van Dijk MA,van de Winkel JG,Parren PW
Fri Oct 01 00:00:00 EDT 2004
Secretory phospholipase A2 mediates cooperative prostaglandin generation by growth factor and cytokine independently of preceding cytosolic phospholipase A2 expression in rat gastric epithelial cells.
The Journal of biological chemistry
Akiba S,Hatazawa R,Ono K,Kitatani K,Hayama M,Sato T
Fri Jun 15 00:00:00 EDT 2001
Collagenase-3 (MMP-13) is expressed by tumor cells in invasive vulvar squamous cell carcinomas.
The American journal of pathology
Johansson N,Vaalamo M,Grénman S,Hietanen S,Klemi P,Saarialho-Kere U,Kähäri VM
Mon Feb 01 00:00:00 EST 1999
Internalized epidermal growth factor receptors participate in the activation of p21(ras) in fibroblasts.
The Journal of biological chemistry
Haugh JM,Huang AC,Wiley HS,Wells A,Lauffenburger DA
Fri Nov 26 00:00:00 EST 1999
Cyclic AMP elevation is sufficient to promote the survival of spinal motor neurons in vitro.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Hanson MG,Shen S,Wiemelt AP,McMorris FA,Barres BA
Tue Sep 15 00:00:00 EDT 1998
