Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This peptide corresponds to 17 amino acid peptide from near the center of human TRBP1
PEP-0451 can be used as a blocking peptide with polyclonal antibody PA5-20331.
The human trans-activation response (TAR) RNA binding protein 1 (TRBP1) was initially identified as a protein that binds to the HIV-1 TAR RNA and activates the long terminal repeat (LTR) expression in the absence and presence of the viral trans-activator Tat. This binding is enhanced by the presence of co-factors such as elongation factor 1-a (EF-1-a), polypyrimidine tract-binding protein (PTB), and the chaperonin-like protein stimulator of TAR RNA-binding proteins (SRB). TRBP1 may act to disengage RNA polymerase II from TAR during transcriptional elongation if the RNA polymerase stalls at the TAR during transcriptional elongation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Probable methyltransferase TARBP1; RP5-827C21.5; TAR (HIV) RNA binding protein 1; TAR (HIV) RNA-binding protein 1; TAR RNA loop binding protein; TAR RNA-binding protein 1; TAR RNA-binding protein of 185 kDa; tRNA methyltransferase 3 homolog; TRP-185
Gene Aliases: TARBP1; TRM3; TRP-185; TRP185
UniProt ID: (Human) Q13395
Entrez Gene ID: (Human) 6894
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