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This peptide corresponds to 17 amino acids near the amino terminus of human TSHZ2.
PEP-1386 can be used as a blocking peptide with polyclonal antibody PA5-34343.
The Teashirt zinc finger homeobox (TSHZ) family comprise a family of evolutionarily conserved transcription factors that, in Drosophila, are active in specific body parts for patterning, but whose function in vertebrates is less clear. In mice, the known three TSHZ proteins are expressed in distinct patterns in the developing and adult brain, suggesting that they play a role in the establishment of regional identity and specification of cell types within the brain. Recent experiments have shown that the expression of TSHZ2 is frequently downregulated in most breast and prostate cancers and its promoter was unmethylated in virtually all cases, suggesting this family of proteins may also be involved in carcinogenesis.
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Protein Aliases: cell growth-inhibiting protein 7; Ovarian cancer-related protein 10-2; OVC10-2; serologically defined colon cancer antigen 33 like; teashirt family zinc finger 2; Teashirt homolog 2; Zinc finger protein 218
Gene Aliases: C20orf17; OVC10-2; TSH2; TSHZ2; ZABC2; ZNF218
UniProt ID: (Human) Q9NRE2
Entrez Gene ID: (Human) 128553
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