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This peptide corresponds to 14 amino acids near the center of human ZBTB1.
PEP-0773 can be used as a blocking peptide with polyclonal antibody PA5-20653.
ZBTB1 acts as a transcriptional repressor. Represses cAMP-responsive element (CRE)-mediated transcriptional activation. In addition, has a role in translesion DNA synthesis. Requires for UV-inducible RAD18 loading, PCNA monoubiquitination, POLH recruitment to replication factories and efficient translesion DNA synthesis. Plays a key role in the transcriptional regulation of T lymphocyte development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Zinc finger and BTB domain-containing protein 1
Gene Aliases: KIAA0997; ZBTB1; ZNF909
UniProt ID: (Human) Q9Y2K1
Entrez Gene ID: (Human) 22890
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