Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This peptide corresponds to 17 amino acids near the amino terminus of human ZC3H12B.
PEP-1041 can be used as a blocking peptide with polyclonal antibody PA5-20927.
ZC3H12B, also known as MCPIP2, is a member of a family of novel CCCH-zinc finger proteins that regulate macrophage activation and may be involved in host immunity and inflammatory diseases. The function of ZC3H12B is not well understood. Unlike other members of the ZC3H12 family, ZC3H12B has a RasGEF domain at the C-terminal of the zinc finger motif, suggesting its potential involvement in Ras-mediated signal transduction. It is highly expressed in brain, thymus, and testis, but unlike ZC3H12A and ZC3H12C, not expressed in macrophages after treatment with lipopolysaccharide (LPS).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MCP-induced protein 2; Probable ribonuclease ZC3H12B; RP3-475B7.1; Zinc finger CCCH domain-containing protein 12B
Gene Aliases: CXorf32; MCPIP2; ZC3H12B
UniProt ID: (Human) Q5HYM0
Entrez Gene ID: (Human) 340554
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support