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Search Thermo Fisher Scientific
This peptide corresponds to 14 amino acid peptide near the amino terminus of human ZIP13.
PEP-1190 can be used as a blocking peptide with polyclonal antibody PA5-21076.
The zinc transporter ZIP13, also known as SLC39A13, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP13 is a multipass membrane protein that belongs to the ZIP transporter subfamily LIV-1. Mutations in ZIP13 have recently been shown to cause a spondylocheiro dysplastic form of Ehlers-Danlos syndrome (SCD-EDS), a generalized skeletal dysplasia involving mainly the spine with clinical abnormalities of the hands in addition to EDS-like features. Other experiments have shown that ZIP13 is required for proper connective tissue development and is involved in BMP/TGF- signaling pathways.
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Protein Aliases: LIV-1 subfamily of ZIP zinc transporter 9; LZT-Hs9; solute carrier family 39 (metal ion transporter), member 13; solute carrier family 39 (zinc transporter), member 13; Solute carrier family 39 member 13; Zinc transporter ZIP13; ZIP-13; Zrt- and Irt-like protein 13
Gene Aliases: LZT-Hs9; SLC39A13; ZIP13
UniProt ID: (Human) Q96H72
Entrez Gene ID: (Human) 91252
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