Product References
Cathepsin C promotes breast cancer lung metastasis by modulating neutrophil infiltration and neutrophil extracellular trap formation.
Cancer cell
Xiao Y,Cong M,Li J,He D,Wu Q,Tian P,Wang Y,Yang S,Liang C,Liang Y,Wen J,Liu Y,Luo W,Lv X,He Y,Cheng DD,Zhou T,Zhao W,Zhang P,Zhang X,Xiao Y,Qian Y,Wang H,Gao Q,Yang QC,Yang Q,Hu G
Mon Mar 08 00:00:00 EST 2021
Aging-induced IL27Ra signaling impairs hematopoietic stem cells.
Blood
He H,Xu P,Zhang X,Liao M,Dong Q,Cong T,Tang B,Yang X,Ye M,Chang Y,Liu W,Wang X,Ju Z,Wang J
Thu Jul 09 00:00:00 EDT 2020
Cytotoxic T cells swarm by homotypic chemokine signalling.
eLife
Galeano Niño JL,Pageon SV,Tay SS,Colakoglu F,Kempe D,Hywood J,Mazalo JK,Cremasco J,Govendir MA,Dagley LF,Hsu K,Rizzetto S,Zieba J,Rice G,Prior V,O'Neill GM,Williams RJ,Nisbet DR,Kramer B,Webb AI,Luciani F,Read MN,Biro M
Tue Oct 13 00:00:00 EDT 2020
MicroRNA-155 Modulates Acute Graft-versus-Host Disease by Impacting T Cell Expansion, Migration, and Effector Function.
Journal of immunology (Baltimore, Md. : 1950)
Zitzer NC,Snyder K,Meng X,Taylor PA,Efebera YA,Devine SM,Blazar BR,Garzon R,Ranganathan P
Fri Jun 15 00:00:00 EDT 2018
Elevated Oxidative Stress Impairs Hematopoietic Progenitor Function in C57BL/6 Substrains.
Stem cell reports
Morales-Hernández A,Martinat A,Chabot A,Kang G,McKinney-Freeman S
Tue Aug 14 00:00:00 EDT 2018
Systematic Screening of Chemokines to Identify Candidates to Model and Create Ectopic Lymph Node Structures for Cancer Immunotherapy.
Scientific reports
Yagawa Y,Robertson-Tessi M,Zhou SL,Anderson ARA,Mulé JJ,Mailloux AW
Wed Nov 22 00:00:00 EST 2017
MiR218 Modulates Wnt Signaling in Mouse Cardiac Stem Cells by Promoting Proliferation and Inhibiting Differentiation through a Positive Feedback Loop.
Scientific reports
Wang Y,Liu J,Cui J,Sun M,Du W,Chen T,Ming X,Zhang L,Tian J,Li J,Yin L,Liu F,Pu Z,Lv B,Hou J,Yu B
Wed Feb 10 00:00:00 EST 2016
PTEN regulates natural killer cell trafficking in vivo.
Proceedings of the National Academy of Sciences of the United States of America
Leong JW,Schneider SE,Sullivan RP,Parikh BA,Anthony BA,Singh A,Jewell BA,Schappe T,Wagner JA,Link DC,Yokoyama WM,Fehniger TA
Tue Feb 17 00:00:00 EST 2015
Recognition of bacterial signal peptides by mammalian formyl peptide receptors: a new mechanism for sensing pathogens.
The Journal of biological chemistry
Bufe B,Schumann T,Kappl R,Bogeski I,Kummerow C,Podgórska M,Smola S,Hoth M,Zufall F
Fri Mar 20 00:00:00 EDT 2015
RGS1 regulates myeloid cell accumulation in atherosclerosis and aortic aneurysm rupture through altered chemokine signalling.
Nature communications
Patel J,McNeill E,Douglas G,Hale AB,de Bono J,Lee R,Iqbal AJ,Regan-Komito D,Stylianou E,Greaves DR,Channon KM
Wed Mar 18 00:00:00 EDT 2015
The Chemokine MIP-1α/CCL3 impairs mouse hippocampal synaptic transmission, plasticity and memory.
Scientific reports
Marciniak E,Faivre E,Dutar P,Alves Pires C,Demeyer D,Caillierez R,Laloux C,Buée L,Blum D,Humez S
Thu Oct 29 00:00:00 EDT 2015
The Src family kinases Hck, Fgr, and Lyn are critical for the generation of the in vivo inflammatory environment without a direct role in leukocyte recruitment.
The Journal of experimental medicine
Kovács M,Németh T,Jakus Z,Sitaru C,Simon E,Futosi K,Botz B,Helyes Z,Lowell CA,Mócsai A
Mon Sep 22 00:00:00 EDT 2014
IL-5 triggers a cooperative cytokine network that promotes eosinophil precursor maturation.
Journal of immunology (Baltimore, Md. : 1950)
Fulkerson PC,Schollaert KL,Bouffi C,Rothenberg ME
Wed Oct 15 00:00:00 EDT 2014
Resistance of LPS-activated bone marrow derived macrophages to apoptosis mediated by dexamethasone.
Scientific reports
Haim YO,Unger ND,Souroujon MC,Mittelman M,Neumann D
Mon Mar 10 00:00:00 EDT 2014
Disease-associated missense mutations in the EVH1 domain disrupt intrinsic WASp function causing dysregulated actin dynamics and impaired dendritic cell migration.
Blood
Worth AJ,Metelo J,Bouma G,Moulding D,Fritzsche M,Vernay B,Charras G,Cory GO,Thrasher AJ,Burns SO
Thu Jan 03 00:00:00 EST 2013
Macrophage-secreted cytokines drive pancreatic acinar-to-ductal metaplasia through NF-κB and MMPs.
The Journal of cell biology
Liou GY,Döppler H,Necela B,Krishna M,Crawford HC,Raimondo M,Storz P
Mon Aug 05 00:00:00 EDT 2013
Adam8 limits the development of allergic airway inflammation in mice.
Journal of immunology (Baltimore, Md. : 1950)
Knolle MD,Nakajima T,Hergrueter A,Gupta K,Polverino F,Craig VJ,Fyfe SE,Zahid M,Permaul P,Cernadas M,Montano G,Tesfaigzi Y,Sholl L,Kobzik L,Israel E,Owen CA
Sat Jun 15 00:00:00 EDT 2013
Chemokine receptor Ccr1 drives neutrophil-mediated kidney immunopathology and mortality in invasive candidiasis.
PLoS pathogens
Lionakis MS,Fischer BG,Lim JK,Swamydas M,Wan W,Richard Lee CC,Cohen JI,Scheinberg P,Gao JL,Murphy PM
Mon Dec 17 00:00:00 EST 2012
Tumor-infiltrating monocytic myeloid-derived suppressor cells mediate CCR5-dependent recruitment of regulatory T cells favoring tumor growth.
Journal of immunology (Baltimore, Md. : 1950)
Schlecker E,Stojanovic A,Eisen C,Quack C,Falk CS,Umansky V,Cerwenka A
Sat Dec 15 00:00:00 EST 2012
An aberrant thymus in CCR5-/- mice is coupled with an enhanced adaptive immune response in fungal infection.
Journal of immunology (Baltimore, Md. : 1950)
Kroetz DN,Deepe GS
Sun May 15 00:00:00 EDT 2011
The interaction between different types of activated RAW 264.7 cells and macrophage inflammatory protein-1 alpha.
Radiation oncology (London, England)
He Z,Zhang H,Yang C,Zhou Y,Zhou Y,Han G,Xia L,Ouyang W,Zhou F,Zhou Y,Xie C
Fri Jul 22 00:00:00 EDT 2011
Pan-CC chemokine neutralization restricts splenocyte egress and reduces inflammation in a model of arthritis.
Journal of immunology (Baltimore, Md. : 1950)
Buatois V,Fagète S,Magistrelli G,Chatel L,Fischer N,Kosco-Vilbois MH,Ferlin WG
Sun Aug 15 00:00:00 EDT 2010
p110gamma and p110delta isoforms of phosphoinositide 3-kinase differentially regulate natural killer cell migration in health and disease.
Proceedings of the National Academy of Sciences of the United States of America
Saudemont A,Garçon F,Yadi H,Roche-Molina M,Kim N,Segonds-Pichon A,Martín-Fontecha A,Okkenhaug K,Colucci F
Tue Apr 07 00:00:00 EDT 2009
Phosphorylation of WASp is a key regulator of activity and stability in vivo.
Proceedings of the National Academy of Sciences of the United States of America
Blundell MP,Bouma G,Metelo J,Worth A,Calle Y,Cowell LA,Westerberg LS,Moulding DA,Mirando S,Kinnon C,Cory GO,Jones GE,Snapper SB,Burns SO,Thrasher AJ
Tue Sep 15 00:00:00 EDT 2009
Endogenous galectin-3 is localized in membrane lipid rafts and regulates migration of dendritic cells.
The Journal of investigative dermatology
Hsu DK,Chernyavsky AI,Chen HY,Yu L,Grando SA,Liu FT
Sun Mar 01 00:00:00 EST 2009
Regulation of immature dendritic cell migration by RhoA guanine nucleotide exchange factor Arhgef5.
The Journal of biological chemistry
Wang Z,Kumamoto Y,Wang P,Gan X,Lehmann D,Smrcka AV,Cohn L,Iwasaki A,Li L,Wu D
Fri Oct 16 00:00:00 EDT 2009
The chemokine receptor CCR5 plays a key role in the early memory CD8+ T cell response to respiratory virus infections.
Immunity
Kohlmeier JE,Miller SC,Smith J,Lu B,Gerard C,Cookenham T,Roberts AD,Woodland DL
Fri Jul 18 00:00:00 EDT 2008
Toll-like receptor ligands synergize through distinct dendritic cell pathways to induce T cell responses: implications for vaccines.
Proceedings of the National Academy of Sciences of the United States of America
Zhu Q,Egelston C,Vivekanandhan A,Uematsu S,Akira S,Klinman DM,Belyakov IM,Berzofsky JA
Tue Oct 21 00:00:00 EDT 2008
Transmigration of neutrophils across inflamed endothelium is signaled through LFA-1 and Src family kinase.
Journal of immunology (Baltimore, Md. : 1950)
Sarantos MR,Zhang H,Schaff UY,Dixit N,Hayenga HN,Lowell CA,Simon SI
Mon Dec 15 00:00:00 EST 2008
CXCL10 blockade protects mice from cyclophosphamide-induced cystitis.
Journal of immune based therapies and vaccines
Sakthivel SK,Singh UP,Singh S,Taub DD,Novakovic KR,Lillard JW
Tue Oct 28 00:00:00 EDT 2008
Inhibition of gluconeogenesis in primary hepatocytes by stromal cell-derived factor-1 (SDF-1) through a c-Src/Akt-dependent signaling pathway.
The Journal of biological chemistry
Liu HY,Wen GB,Han J,Hong T,Zhuo D,Liu Z,Cao W
Fri Nov 07 00:00:00 EST 2008
Inhibition of G alpha i2 activation by G alpha i3 in CXCR3-mediated signaling.
The Journal of biological chemistry
Thompson BD,Jin Y,Wu KH,Colvin RA,Luster AD,Birnbaumer L,Wu MX
Fri Mar 30 00:00:00 EDT 2007
Critical role for CCR5 in the function of donor CD4+CD25+ regulatory T cells during acute graft-versus-host disease.
Blood
Wysocki CA,Jiang Q,Panoskaltsis-Mortari A,Taylor PA,McKinnon KP,Su L,Blazar BR,Serody JS
Tue Nov 01 00:00:00 EST 2005
Leukotriene B4, an activation product of mast cells, is a chemoattractant for their progenitors.
The Journal of experimental medicine
Weller CL,Collington SJ,Brown JK,Miller HR,Al-Kashi A,Clark P,Jose PJ,Hartnell A,Williams TJ
Mon Jun 20 00:00:00 EDT 2005
A novel signaling pathway mediates the inhibition of CCL3/4 expression by prostaglandin E2.
The Journal of biological chemistry
Jing H,Yen JH,Ganea D
Fri Dec 31 00:00:00 EST 2004
MIP-1alpha and MIP-1beta differentially mediate mucosal and systemic adaptive immunity.
Blood
Lillard JW,Singh UP,Boyaka PN,Singh S,Taub DD,McGhee JR
Sat Feb 01 00:00:00 EST 2003
Hematopoietic stem cells are uniquely selective in their migratory response to chemokines.
The Journal of experimental medicine
Wright DE,Bowman EP,Wagers AJ,Butcher EC,Weissman IL
Mon May 06 00:00:00 EDT 2002
The intestinal chemokine thymus-expressed chemokine (CCL25) attracts IgA antibody-secreting cells.
The Journal of experimental medicine
Bowman EP,Kuklin NA,Youngman KR,Lazarus NH,Kunkel EJ,Pan J,Greenberg HB,Butcher EC
Mon Jan 21 00:00:00 EST 2002
CCL7 and CXCL10 orchestrate oxidative stress-induced neutrophilic lung inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Michalec L,Choudhury BK,Postlethwait E,Wild JS,Alam R,Lett-Brown M,Sur S
Tue Jan 15 00:00:00 EST 2002
BLTR mediates leukotriene B(4)-induced chemotaxis and adhesion and plays a dominant role in eosinophil accumulation in a murine model of peritonitis.
The Journal of experimental medicine
Tager AM,Dufour JH,Goodarzi K,Bercury SD,von Andrian UH,Luster AD
Mon Aug 07 00:00:00 EDT 2000
