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Product Details
RP-88219
Product Specifications
Species
Mouse
Expression System
HEK293 cells
Amino acid sequence
Mouse CD52, amino acids Met1-Lys46 (Accession # NP_038734.1) with a C-terminal human IgG1 Fc region
Tag
Fc-tag
Molecular weight
29 kDa
Class
Recombinant
Type
Protein
Purity
>95% as determined by SDS-PAGE.
Endotoxin concentration
<1.0 EU/µg
Conjugate
Form
Lyophilized
Purification
purified
Storage buffer
PBS, pH 7.4, with 0.01% mannitol, 5-8% trehalose, 0.01% Tween 80
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
It is recommended that the protein be aliquoted for optimal storage.
It is recommended that sterile water (400 µL) be added to the vial to prepare a stock solution of 0.25 mg/mL.
Concentration is measured by UV.
Target Information
CD52, also known as CAMPATH-1 antigen, is a glycoprotein that is expressed on the surface of various immune cells, including T and B lymphocytes, natural killer cells, and monocytes. It is involved in the regulation of immune responses and is being studied as a potential therapeutic target in various diseases, including multiple sclerosis, chronic lymphocytic leukemia, and autoimmune disorders. CD52 is the target of alemtuzumab, a monoclonal antibody that is used to treat these conditions by depleting immune cells that express CD52.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CAMPATH-1 antigen; CD52; CD52 antigen; Lymphocyte differentiation antigen B7
Gene Aliases: AI463198; B7; B7-Ag; CAMPATH-1; Cd52; Cdw52; CLS1; MB7
UniProt ID: (Mouse) Q64389
Entrez Gene ID: (Mouse) 23833
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