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Product Details
RP-88221
Product Specifications
Species
Mouse
Expression System
HEK293 cells
Amino acid sequence
Mouse FCGR1, amino acids Met1-Pro297 (Accession # NP_034316.1) with a C-terminal His-tag
Tag
His-tag
Molecular weight
45-50 kDa
Class
Recombinant
Type
Protein
Purity
>97% as determined by SDS-PAGE.
Endotoxin concentration
<1.0 EU/µg
Activity
Measured by its binding ability in a functional ELISA. Immobilized mouse CD64-His at 10 µg/ml (100 µL/well) can bind biotinylated human IgG1, The EC50 of biotinylated human IgG1 is 0.07-0.17 µg/ml.
Conjugate
Form
Lyophilized
Purification
purified
Storage buffer
PBS, pH 7.4, with 0.01% mannitol, 5-8% trehalose, 0.01% Tween 80
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
It is recommended that the protein be aliquoted for optimal storage.
It is recommended that sterile water (400 µL) be added to the vial to prepare a stock solution of 2.5 mg/mL.
Concentration is measured by UV.
Target Information
CD64 (FCGR1A) encodes a protein that plays an important role in the immune response. CD64 is a high-affinity Fc-gamma receptor and is one of three related gene family members located on chromosome 1. CD64 plays an important role in the immune response and its dysfunction has been studied in cervical adenitis and tetrasomy 21.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD64; CD64 antigen; Fc-gamma receptor 1; Fc-gamma RI; FcgRI; FcRI; FLJ18345; High affinity immunoglobulin gamma Fc receptor I; IgG Fc receptor I; IgG high affinity Fc receptor; RP11-196G18.2
Gene Aliases: AI323638; AV092959; CD64; Fcg1; FcgammaRI; Fcgr1; IGGHAFC
UniProt ID: (Mouse) P26151
Entrez Gene ID: (Mouse) 14129
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