Product References
Intrahippocampal injection of IL-1β upregulates Siah1-mediated degradation of synaptophysin by activation of the ERK signaling in male rat.
Journal of neuroscience research
Zhou Q,Lin L,Li H,Li Y,Liu N,Wang H,Jiang S,Li Q,Chen Z,Lin Y,Jin H,Deng Y
400-01B was used in In vivo experiments to suggest that exogenous IL-1β can suppress syn protein level and glutamate release.
Thu Jun 01 00:00:00 EDT 2023
Whole Transcriptome Mapping Identifies an Immune- and Metabolism-Related Non-coding RNA Landscape Remodeled by Mechanical Stress in IL-1β-Induced Rat OA-like Chondrocytes.
Frontiers in genetics
Zhang J,Hao X,Chi R,Liu J,Shang X,Deng X,Qi J,Xu T
400-01B was used in In vitro experiments to investigate the effects of mechanical stress on IL-1β-induced OA-like chondrocytes and non-coding transcriptome signature of mechanical stress.
Tue Mar 22 00:00:00 EDT 2022
Moderate mechanical stress suppresses the IL-1β-induced chondrocyte apoptosis by regulating mitochondrial dynamics.
Journal of cellular physiology
Zhang J,Hao X,Chi R,Qi J,Xu T
400-01B was used in In vitro experiments to reveal the effects of mechanical stress upon mitochondrial dynamics in chondrocyte.
Mon Nov 01 00:00:00 EDT 2021
CCR5 signaling promotes lipopolysaccharide-induced macrophage recruitment and alveolar developmental arrest.
Cell death & disease
Chen Z,Xie X,Jiang N,Li J,Shen L,Zhang Y
Mon Feb 15 00:00:00 EST 2021
NLRP2 Is Overexpressed in Spinal Astrocytes at the Peak of Mechanical Pain Sensitivity during Complete Freund Adjuvant-Induced Persistent Pain.
International journal of molecular sciences
Ducza L,Szücs P,Hegedűs K,Bakk E,Gajtkó A,Wéber I,Holló K
400-01B was used in Immunohistochemistry to study a ligand of IL-1R1, termed interleukin-1β (IL-1β), is also significantly overexpressed at the peak of mechanical pain sensitivity in the Complete Freund adjuvant (CFA)-evoked pain model.
Fri Oct 22 00:00:00 EDT 2021
STING promotes senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the NF-κB signaling pathway.
Cell death & disease
Guo Q,Chen X,Chen J,Zheng G,Xie C,Wu H,Miao Z,Lin Y,Wang X,Gao W,Zheng X,Pan Z,Zhou Y,Wu Y,Zhang X
Mon Jan 04 00:00:00 EST 2021
Hypertonic saline mediates the NLRP3/IL-1β signaling axis in microglia to alleviate ischemic blood-brain barrier permeability by downregulating astrocyte-derived VEGF in rats.
CNS neuroscience & therapeutics
Wang QS,Ding HG,Chen SL,Liu XQ,Deng YY,Jiang WQ,Li Y,Huang LQ,Han YL,Wen MY,Wang MQ,Zeng HK
400-01B was used in In vitro experiments to investigate hypertonic saline treatment of alleviating the blood-brain barrier and affects of VEGF and NLRP3.
Thu Oct 01 00:00:00 EDT 2020
Inhibition of Rac1 activity by NSC23766 prevents cartilage endplate degeneration via Wnt/β-catenin pathway.
Journal of cellular and molecular medicine
Jiang C,Sun ZM,Zhu DC,Guo Q,Xu JJ,Lin JH,Chen ZX,Wu YS
Sun Mar 01 00:00:00 EST 2020
MHC/class-II-positive cells inhibit corticosterone of adrenal gland cells in experimental arthritis: a role for IL-1β, IL-18, and the inflammasome.
Scientific reports
Stangl H,Krammetsvogl A,Lesiak M,Wolff C,Straub RH
Tue Oct 13 00:00:00 EDT 2020
Location and Plasticity of the Sodium Spike Initiation Zone in Nociceptive Terminals In Vivo.
Neuron
Goldstein RH,Barkai O,Íñigo-Portugués A,Katz B,Lev S,Binshtok AM
Wed May 22 00:00:00 EDT 2019
Exosomes from tendon stem cells promote injury tendon healing through balancing synthesis and degradation of the tendon extracellular matrix.
Journal of cellular and molecular medicine
Wang Y,He G,Guo Y,Tang H,Shi Y,Bian X,Zhu M,Kang X,Zhou M,Lyu J,Yang M,Mu M,Lai F,Lu K,Chen W,Zhou B,Zhang J,Tang K
Thu Aug 01 00:00:00 EDT 2019
Upregulation of caveolin-1 and its colocalization with cytokine receptors contributes to beta cell apoptosis.
Scientific reports
Bae GD,Park EY,Kim K,Jang SE,Jun HS,Oh YS
Thu Nov 14 00:00:00 EST 2019
Mesenchymal stem cells overexpressing heme oxygenase-1 ameliorate lipopolysaccharide-induced acute lung injury in rats.
Journal of cellular physiology
Chen X,Wu S,Tang L,Ma L,Wang F,Feng H,Meng J,Han Z
400-01B was used in In vitro experiments to provide a novel insight into MSC-based therapeutic strategies for treating ALI/ARDS.
Wed May 01 00:00:00 EDT 2019
Glucagon-like peptide-1 receptor regulates endoplasmic reticulum stress-induced apoptosis and the associated inflammatory response in chondrocytes and the progression of osteoarthritis in rat.
Cell death & disease
Chen J,Xie JJ,Shi KS,Gu YT,Wu CC,Xuan J,Ren Y,Chen L,Wu YS,Zhang XL,Xiao J,Wang DZ,Wang XY
Mon Feb 12 00:00:00 EST 2018
Platelets Mediate Host Defense against Staphylococcus aureus through Direct Bactericidal Activity and by Enhancing Macrophage Activities.
Journal of immunology (Baltimore, Md. : 1950)
Ali RA,Wuescher LM,Dona KR,Worth RG
Sun Jan 01 00:00:00 EST 2017
Mechanisms and modulation of microvesicle uptake in a model of alveolar cell communication.
The Journal of biological chemistry
Schneider DJ,Speth JM,Penke LR,Wettlaufer SH,Swanson JA,Peters-Golden M
Fri Dec 22 00:00:00 EST 2017
Minocycline attenuates bone cancer pain in rats by inhibiting NF-κB in spinal astrocytes.
Acta pharmacologica Sinica
Song ZP,Xiong BR,Guan XH,Cao F,Manyande A,Zhou YQ,Zheng H,Tian YK
400-01B was used in Cell Culture to study mechanisms underlying the anti-nociceptive effect of minocycline on bone cancer pain (BCP) in rats and show that minocycline effectively alleviates BCP by inhibiting the NF-κB signaling pathway in spinal astrocytes.
Wed Jun 01 00:00:00 EDT 2016
Experimental Anti-Inflammatory Drug Semapimod Inhibits TLR Signaling by Targeting the TLR Chaperone gp96.
Journal of immunology (Baltimore, Md. : 1950)
Wang J,Grishin AV,Ford HR
Wed Jun 15 00:00:00 EDT 2016
IL-1β induces hypomyelination in the periventricular white matter through inhibition of oligodendrocyte progenitor cell maturation via FYN/MEK/ERK signaling pathway in septic neonatal rats.
Glia
Xie D,Shen F,He S,Chen M,Han Q,Fang M,Zeng H,Chen C,Deng Y
400-01B was used in Cell Culture to suggest that following LPS injection, microglia are activated and produce IL-1β in the PWM in the neonatal rats.
Fri Apr 01 00:00:00 EDT 2016
Prolyl-4-hydroxylase domain protein 2 controls NF-κB/p65 transactivation and enhances the catabolic effects of inflammatory cytokines on cells of the nucleus pulposus.
The Journal of biological chemistry
Li J,Yuan W,Jiang S,Ye W,Yang H,Shapiro IM,Risbud MV
Fri Mar 13 00:00:00 EDT 2015
Rapamycin and interleukin-1β impair brain-derived neurotrophic factor-dependent neuron survival by modulating autophagy.
The Journal of biological chemistry
Smith ED,Prieto GA,Tong L,Sears-Kraxberger I,Rice JD,Steward O,Cotman CW
Fri Jul 25 00:00:00 EDT 2014
Hypertonic saline alleviates cerebral edema by inhibiting microglia-derived TNF-α and IL-1β-induced Na-K-Cl Cotransporter up-regulation.
Journal of neuroinflammation
Huang LQ,Zhu GF,Deng YY,Jiang WQ,Fang M,Chen CB,Cao W,Wen MY,Han YL,Zeng HK
400-01B was used in Cell Culture to explore if alleviation of cerebral edema by 10% HS might be effected through down-regulation of inflammatory mediator expression in the microglia, and thus result in decreased NKCC1 expression in astrocytes in the cerebral cortex bordering the ischemic core.
Wed Jun 11 00:00:00 EDT 2014
Microbiota-induced IL-1β, but not IL-6, is critical for the development of steady-state TH17 cells in the intestine.
The Journal of experimental medicine
Shaw MH,Kamada N,Kim YG,Núñez G
Mon Feb 13 00:00:00 EST 2012
Posttraumatic invasion of monocytes across the blood-cerebrospinal fluid barrier.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
Szmydynger-Chodobska J,Strazielle N,Gandy JR,Keefe TH,Zink BJ,Ghersi-Egea JF,Chodobski A
Sun Jan 01 00:00:00 EST 2012
Ferroportin-1 is a 'nuclear'-negative acute-phase protein in rat liver: a comparison with other iron-transport proteins.
Laboratory investigation; a journal of technical methods and pathology
Naz N,Malik IA,Sheikh N,Ahmad S,Khan S,Blaschke M,Schultze F,Ramadori G
Fri Jun 01 00:00:00 EDT 2012
COUP-TFII controls mouse pancreatic β-cell mass through GLP-1-β-catenin signaling pathways.
PloS one
Boutant M,Ramos OH,Tourrel-Cuzin C,Movassat J,Ilias A,Vallois D,Planchais J,Pégorier JP,Schuit F,Petit PX,Bossard P,Maedler K,Grapin-Botton A,Vasseur-Cognet M
Mon Jun 04 00:00:00 EDT 2012
Intraperitoneal but not intravenous cryopreserved mesenchymal stromal cells home to the inflamed colon and ameliorate experimental colitis.
PloS one
Castelo-Branco MT,Soares ID,Lopes DV,Buongusto F,Martinusso CA,do Rosario A,Souza SA,Gutfilen B,Fonseca LM,Elia C,Madi K,Schanaider A,Rossi MI,Souza HS
Fri Jul 13 00:00:00 EDT 2012
Trigeminal-rostral ventromedial medulla circuitry is involved in orofacial hyperalgesia contralateral to tissue injury.
Molecular pain
Chai B,Guo W,Wei F,Dubner R,Ren K
Tue Oct 23 00:00:00 EDT 2012
Autophagy in rat annulus fibrosus cells: evidence and possible implications.
Arthritis research & therapy
Shen C,Yan J,Jiang LS,Dai LY
Tue Aug 16 00:00:00 EDT 2011
Changes in gene expression of DOR and other thyroid hormone receptors in rat liver during acute-phase response.
Cell and tissue research
Malik IA,Baumgartner BG,Naz N,Sheikh N,Moriconi F,Ramadori G
Mon Nov 01 00:00:00 EDT 2010
Inhibitory effect of interleukin-1beta on angiotensin II-induced connective tissue growth factor and type IV collagen production in cultured mesangial cells.
American journal of physiology. Renal physiology
Sánchez-López E,Rodriguez-Vita J,Cartier C,Rupérez M,Esteban V,Carvajal G,Rodrígues-Díez R,Plaza JJ,Egido J,Ruiz-Ortega M
Tue Jan 01 00:00:00 EST 2008
x-Irradiation in rat liver: consequent upregulation of hepcidin and downregulation of hemojuvelin and ferroportin-1 gene expression.
Radiology
Christiansen H,Sheikh N,Saile B,Reuter F,Rave-Fränk M,Hermann RM,Dudas J,Hille A,Hess CF,Ramadori G
Mon Jan 01 00:00:00 EST 2007
Enhanced excitability of nociceptive trigeminal ganglion neurons by satellite glial cytokine following peripheral inflammation.
Pain
Takeda M,Tanimoto T,Kadoi J,Nasu M,Takahashi M,Kitagawa J,Matsumoto S
Tue May 01 00:00:00 EDT 2007
System xc- and glutamate transporter inhibition mediates microglial toxicity to oligodendrocytes.
Journal of immunology (Baltimore, Md. : 1950)
Domercq M,Sánchez-Gómez MV,Sherwin C,Etxebarria E,Fern R,Matute C
Tue May 15 00:00:00 EDT 2007
Differential pattern of inflammatory molecule regulation in intestinal epithelial cells stimulated with IL-1.
Journal of immunology (Baltimore, Md. : 1950)
Yan SR,Joseph RR,Wang J,Stadnyk AW
Sun Oct 15 00:00:00 EDT 2006
Tenascin-R is antiadhesive for activated microglia that induce downregulation of the protein after peripheral nerve injury: a new role in neuronal protection.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Angelov DN,Walther M,Streppel M,Guntinas-Lichius O,Neiss WF,Probstmeier R,Pesheva P
Sat Aug 15 00:00:00 EDT 1998
