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This gene encodes one of seven subunits of the human Arp2/3 protein complex. This complex controls actin polymerization in cells and has been conserved throughout eukaryotic evolution. This gene encodes the p20 subunit, which is necessary for actin nucleation and high-affinity binding to F-actin. Alternative splicing results in multiple transcript variants. Naturally occurring read-through transcription exists between this gene and the downstream tubulin tyrosine ligase-like family, member 3, which results in the production of a fusion protein.
20kDa; 5330419I20Rik; actin related protein 2/3 complex subunit 4; actin related protein 2/3 complex subunit 4, 20kDa; actin related protein 2/3 complex, subunit 4; actin related protein 2/3 complex, subunit 4, 20kDa; actin-related protein 2/3 complex subunit 4; AI327076; ARC20; arp2/3 complex 20 kDa subunit; arp2/3 protein complex subunit p20; ARPC4; fa07b12; MGC13544; p20-ARC; wu:fa07b12; zgc:77932
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