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ATIC is a 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase which helps catalyze the penultimate and final steps of the de novo purine biosynthetic pathway. The human ATIC cDNA encodes a deduced 591-amino acid protein that is 81% identical to the chicken sequence.
153761_at; 2610509C24Rik; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase L homeolog; 5-aminoimidazole-4-carboxamide-1-beta-D-ribonucleotide transformylase/inosinicase; AA536954; AICAR; AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme; AICAR transformylase; AICARFT; AICARFT/IMPCHASE; atic; atic.L; AW212393; BEST:GH11240; Bifunctional purine biosynthesis protein PURH; Bifunctional purine biosynthesis protein PURH, N-terminally processed; CG11089; CG11089-PA; CG11089-PB; CT30991; Dmel\CG11089; Dmel_CG11089; epididymis secretory sperm binding protein Li 70p; HEL-S-70p; IMP cyclohydrolase; IMP synthase; IMPCHASE; Inosinicase; OK/SW-cl.86; Phosphoribosylaminoimidazolecarboxamide formyltransferase; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PURH; RE29555p; uncharacterized protein; XELAEV_18044849mg
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