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Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression (PubMed:21475249). Can suppress ATXN1 cytotoxicity in spinocerebellar ataxia type 1 (SCA1). In concert with CIC and ATXN1, involved in brain development. [UniProt]
ankyrin repeat and SOCS box containing 16; ankyrin repeat and SOCS box protein 16; ankyrin repeat and SOCS box-containing 16; ankyrin repeat and SOCS box-containing protein 16; ASB16; ASB-16; ataxin 1 like; ataxin 1-like; ataxin-1-like; ATXN1L; BOAT; BOAT1; Brother of ataxin-1; brother of ATXN1
400 µL
100 µL
100 µL
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