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Negatively regulates the transcriptional activator activity of SPIN1 via inhibition of its histone methyl-binding ability. Represses the expression of a number of SPIN1-regulated genes and the SPIN1-mediated activation of the Wnt signaling pathway. Can also inhibit the histone methyl-binding abilities of SPIN2A, SPIN2B, SPIN3 and SPIN4 (PubMed:29061846). [UniProt]
C11orf84; chromosome 11 open reading frame 84; hypothetical protein BC007540; SPIN1-docking protein; Spindlin interactor and repressor of chromatin-binding protein; SPINDOC; SPIN-DOC; uncharacterized protein C11orf84
100 µL
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