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The protein encoded by this gene is primarily found in endothelial cells and blood vessels, where it is involved in cell shape changes and EGF-induced cell migration. It can enhance the activation of vascular endothelial growth factor receptor-2/kinase insert domain receptor and also promote the proteolysis of internalized kinase insert domain receptor. This gene may play a role in angiogenesis-related diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014].
1110006O17Rik; apoptosis regulator through modulating IAP expression; ARIA; Ecscr; ECSM2; endothelial cell surface expressed chemotaxis and apoptosis regulator; endothelial cell-specific chemotaxis regulator; Endothelial cell-specific molecule 2
100 µg
100 µL
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