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This gene encodes the transcriptionally active subunit of the SIII (or elongin) transcription elongation factor complex, which also includes two regulatory subunits, elongins B and C. This complex acts to increase the rate of RNA chain elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites along the DNA template. Whereas a related protein with similar function, elongin A, is ubiquitously expressed, the encoded protein is specifically expressed in the testis, suggesting it may have a role in spermatogenesis.
110kDa; AA408125; El; EloA; EloA2; Elongin 110 kDa subunit; elongin A; Elongin A2; elongin-A; Elongin-A2; MSTP059; RNA polymerase II transcription factor elongin subunit A (110 kDa); RNA polymerase II transcription factor SIII subunit A; RNA polymerase II transcription factor SIII subunit A1; SIII; SIII p110; TCEB3; TCEB3A; TCEB3B; TCEB3L; transcription elongation factor B (SIII), polypeptide 3; transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A); transcription elongation factor B alpha subunit; transcription elongation factor B polypeptide 3; transcription elongation factor B subunit 3
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