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GADD45G gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta.
AI327420; C86281; CR6; Cytokine-responsive protein CR6; DDIT2; DDIT-2; DNA damage-inducible transcript 2 protein; GADD45G; GADD45gamma; GADD45-gamma; gadd-related protein, 17 kD; growth arrest and DNA damage inducible; growth arrest and DNA damage inducible gamma; growth arrest and DNA damage-inducible protein GADD45 gamma; growth arrest and DNA-damage-inducible 45 gamma; growth arrest and DNA-damage-inducible protein GADD45 gamma; growth arrest and DNA-damage-inducible, gamma; GRP17; OIG37; RP11-260L6.1
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