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This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants have been identified in this gene.
ADP-ribosylation factor binding protein 3; ADP-ribosylation factor-binding protein GGA3; ADP-ribosylation factor-binding protein GGA3a; C230037M19Rik; Gga3; gga3a; ggolgi-associated, gamma adaptin ear containing, ARF binding protein 3; golgi associated, gamma adaptin ear containing, ARF binding protein 3; golgi associated, gamma adaptin ear containing, ARF binding protein 3a; golgi-localized, gamma ear-containing, ARF-binding protein 3; im:7144559; KIAA0154; mKIAA0154; si:ch211-108p22.4
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