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Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. [UniProt]
G protein-coupled receptor 109B; GPR109B; G-protein coupled receptor 109B; G-protein coupled receptor HM74; G-protein coupled receptor HM74B; GTP-binding protein; HCA3; HCAR3; HM74; HM74B; hydroxycarboxylic acid receptor 3; hydroxy-carboxylic acid receptor 3; Niacin receptor 2; NIACR2; Nicotinic acid receptor 2; PUMAG; Puma-g; putative chemokine receptor
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