Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Calponin, a thin filament associated protein is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. Calponin is expressed in smooth muscle and tissues containing significant amounts of smooth muscle. Two isoforms of calponin exist whose molecular weights are 34kDa and 29kDa. Expression of the 29kDa form is primarily restricted to muscle of the urogenital tract. The expression of calponin has also been demonstrated in myoepithelial cells from benign and malignant breast lesions. It stains smooth muscle, myoepithelial cells, myofibroblasts, keratinocytes and nerve fibers. It identifies myoepithelial cells in breast lesions, and helps differentiate breast collagenous spherulosis (positive) from adenoid cystic carcinoma. Adenoid cystic carcinoma in salivary gland tumors is calponin positive.
AF465352; BTB/POZ domain-containing protein KCTD11; C17orf36; KCASH1; KCASH1 protein; KCTD11; potassium channel tetramerisation domain containing 11; potassium channel tetramerization domain containing 11; potassium channel tetramerization domain-containing protein 11; REN; REN/KCTD11; retinoic acid, EGF, and NGF upregulated; retinoic acid, EGF, NGF induced gene protein; retinoic acid, EGF, NGF induced gene/potassium channel tetramerization domain containing 11; RING-type E3 ubiquitin transferase KCTD11; RING-type E3 ubiquitin transferase subunit KCTD11
100 µL
100 µg
100 µL
100 µL
100 µL
Searching for an antibody we don't offer? We make custom antibodies for specific targets, species and applications.
More than 18,000 custom antibodies created so far.
Talk to a specialist nowIf an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support