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Is a positive regulator of ciliogenesis, playing a crucial role in the initial steps of axoneme extension. It acts as a substrate-adapter for CUL3-RING ubiquitin ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of TCHP, a protein involved in ciliogenesis down-regulation (PubMed:25270598). May be involved in endoplasmic reticulum calcium ion homeostasis (PubMed:25983243).
2900008M13Rik; AA414907; AW742389; BTB/POZ domain-containing protein KCTD17; KCTD17; LOW QUALITY PROTEIN: BTB/POZ domain-containing protein KCTD17; N28155; potassium channel tetramerisation domain containing 17; potassium channel tetramerization domain containing 17; RGD1311154
50 µg
100 µL
100 µL
100 µL
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