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Lymphotactin, otherwise known as XCL1, is a member of the C-chemokine family that uniquely acts as a chemoattractant for lymphocytes, but not monocytes or neutrophils, suggesting an important regulatory role in lymphocyte trafficking and inflammation. Lymphotactin, shown to signal through chemokine XC receptor 1 (XCR1), is detected at the highest level in the spleen and at low levels in the lungs, small intestine and colon, and is abundantly and selectively expressed by activated T cells, in particular CD8+ T cells, and is also produced by NK cells.
AI661682; ATAC; C motif chemokine 1; chemokine (C motif) ligand 1; cytokine SCM-1; Lptn; LTN; Lymphotactin; lymphotaxin; SCM1; SCM-1; SCM1A; SCM-1a; SCM1alpha; SCM-1alpha; SCM-1-alpha; SCM1beta; SCM-1beta; SCM-1-beta; SCYC1; single cysteine motif 1a; small inducible cytokine subfamily C, member 1 (lymphotactin); small-inducible cytokine C1; XC chemokine ligand 1; X-C motif chemokine ligand 1; XCL1
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