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MZB1 associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity. Isoform 2 may be involved in regulation of apoptosis. Helps to diversify peripheral B-cell functions by regulating Ca(2+) stores, antibody secretion and integrin activation.; Acts as a hormone-regulated adipokine/proinflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes. May have a role in the onset of insulin resistance.
caspase-2 binding protein; HSPC190; marginal zone B and B1 cell specific protein; marginal zone B and B1 cell-specific protein; marginal zone B- and B1-cell-specific protein; MEDA7; MEDA-7; Mesenteric estrogen-dependent adipose 7; mesenteric oestrogen-dependent adipose gene- 7; MGC29506; MZB1; PACAP; pERp1; plasma cell-induced ER protein 1; plasma cell-induced resident endoplasmic reticulum protein; Plasma cell-induced resident ER protein; proapoptotic caspase adapter protein; proapoptotic caspase adaptor protein
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