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Required for progression through the G1 and S phases of the cell cycle and for S phase entry. Activates transcription of the histone H2A, histone H2B, histone H3 and histone H4 genes in conjunction with MIZF. Also positively regulates the ATM, MIZF and PRKDC promoters. Transcriptional activation may be accomplished at least in part by the recruitment of the NuA4 histone acetyltransferase (HAT) complex to target gene promoters.
CAND3; E14; E14/NPAT; NPAT; Nuclear protein of the ataxia telangiectasia mutated locus; nuclear protein of the ATM locus; nuclear protein, ataxia-telangiectasia locus; nuclear protein, coactivator of histone transcription; nuclear protein, co-activator of histone transcription; p220; Protein NPAT
100 µL
100 µL
10 µL
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