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With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Adds multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator.
1600027K07Rik; AU019165; AW538011; BC003223; C6orf68; Cis-prenyltransferase subunit NgBR; D10Ertd438e; dehydrodolichyl diphosphate syntase complex subunit NUS1; dehydrodolichyl diphosphate syntase complex subunit NUS1 pseudogene; dehydrodolichyl diphosphate synthase complex subunit NUS1; di-trans,poly-cis-decaprenylcistransferase; MGC:7199; NgBR; Nogo-B receptor; Nuclear undecaprenyl pyrophosphate synthase 1 homolog; nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae); Nus1; NUS1 dehydrodolichyl diphosphate synthase subunit; NUS1, dehydrodolichyl diphosphate synthase subunit; RGD1307879; TANGO14; transport and golgi organization 14 homolog
100 µL
100 µg
100 µL
100 µL
100 µL
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