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G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more thana thousandmembers currently predicted to exist.All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms. An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors. Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs. This "turn-off" activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates.
Olfactory receptor 10R2; olfactory receptor family 10 subfamily R member 2; olfactory receptor OR1-8; olfactory receptor, family 10, subfamily R, member 2; OR10R2; OR10R2Q; OR1-8
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50 µg
25 µg
100 µL
50 µg
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100 µL
100 µL
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