Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated (t(1;22)(p36. 1;q12). The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene.
8430401L15Rik; AI447519; BTB/POZ domain zinc finger transcription factor; BTB-POZ domain zinc finger transcription factor; dJ400N23; Mazr; MAZ-related factor; Patz; PATZ1; POZ (BTB) and AT hook containing zinc finger 1; POZ-, AT hook-, and zinc finger-containing protein 1; POZ/BTB and AT hook containing zinc finger 1; POZ-AT hook-zinc finger protein; protein kinase A RI subunit alpha-associated protein; RIAZ; transcription factor (MAZ-related) MAZR; ZBTB19; Zfp278; zi; Zinc finger and BTB domain-containing protein 19; zinc finger protein 278; Zinc finger sarcoma gene protein; ZNF278; ZSG
150 µL
100 µL
100 µL
100 µL
100 µg
100 µg
100 µg
100 µg
50 µg
100 µL
100 µL
100 µL
Searching for an antibody we don't offer? We make custom antibodies for specific targets, species and applications.
More than 18,000 custom antibodies created so far.
Talk to a specialist nowIf an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support