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This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 7 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene is located in a major X/Y block of homology and its most closely related cadherin superfamily member is located in this homologous region on the X chromosome. The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system. Transcripts arising from alternative splicing encode isoforms with N- and C-terminal variation.
KIAA1326; PCDH11; PCDH11X; PCDH11Y; PCDH22; PCDH-PC; PCDHX; PCDH-X; PCDHY; PCDH-Y; PPP1R119; protein phosphatase 1, regulatory subunit 119; protocadherin 11 X-linked; protocadherin 11 Y-linked; protocadherin 11X; protocadherin 22; protocadherin on the X chromosome; Protocadherin on the Y chromosome; protocadherin prostate cancer; Protocadherin-11; Protocadherin-11 X-linked; protocadherin-11 Y-linked; Protocadherin-22; Protocadherin-PC; protocadherin-S
100 µg
100 µg
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