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Phosducin-like proteins (PhLPs) are a conserved family of proteins with thioredoxin-like domains that were initially identified as modulators of G protein signaling. PDCL3 is highly homologous to PDCL and shares an N-terminal helix domain and a C-terminal thioredoxin-fold (Trx-fold) domain. Along with the related protein PDCL2, PDCL3 interacts with the chaperonin CCT and modulates CCT-mediated actin and tubulin folding. Modulation of PDCL3 levels by MAPK phosphorylation and RhoA-dependent changes also promote cytoskeletal remodeling.
1110061A19Rik; C80025; HTPHLP; IAP-associated factor VIAF1; PDCL3; PhLP2A; PHLP3; phosducin like 3; phosducin-like 3; phosducin-like protein 3; PhPL3; VIAF; VIAF1; VIAF-1; Viral IAP-associated factor 1
100 µL
100 µg
100 µL
100 µL
100 µg
100 µg
100 µg
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