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The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. This protein is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosynthesis. This gene and PAICS/AIRC, a bifunctional enzyme catalyzing steps six and seven in the purine nucleotide biosynthesis pathway, are located in close proximity on chromosome 4.
5730454C12Rik; AA408689; AA675351; AI507113; Amidophosphoribosyltransferase; amidophosphoribosyltransferase proprotein; amidophosphoribosyltransferase-like protein; ATASE; C79945; EC 2.4.2.14; EGK_15868; glutamine phosphoribosylpyrophosphatate amidotransferase; glutamine phosphoribosylpyrophosphate amidotransferase; glutamine PRPP amidotransferase; GPAT; phosphoribosyl pyrophosphate amidotransferase; PPAT; PRAT
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