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Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class II-containing vesicles along the actin cytoskeleton in dendritic cells. Involved in membrane recycling. Interacts with several phosphatidylinositol phosphate species, including phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 4,5-bisphosphate. [UniProt]
ADP-ribosylation factor guanine nucleotide-exchange factor 6; EFA6B; Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 B; exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B; exchange factor for ARF6 B; PH and SEC7 domain-containing protein 4; pleckstrin and Sec7 domain containing 4; pleckstrin homology and SEC7 domain-containing protein 4; PSD4; SEC7 homolog; telomeric of interleukin-1 cluster protein; TIC
100 µL
100 µL
100 µL
100 µL
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