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The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination.
ATR2; DNA repair and recombination protein RAD54-like; h hRAD54; hHR54; HR54; hRAD54; MGC2094; mHR54; mRAD54; MRXHF1; Rad54; RAD54 homolog; RAD54 like (S. cerevisiae); RAD54A; RAD54L; RAD54-like (S. cerevisiae); RP5-875J14.1; SFM1; SHS; XH2; XNP; ZNF-HX
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