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RAP2A is a small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading.
5830461H18Rik; KREV; K-REV; RAP2; RAP2, member of RAS oncogene family (K-rev); Rap2a; Rap2A GTPase; RAP2A, member of RAS oncogene family; RAS related protein 2a; ras-related protein Rap-2a; RbBP-30; RP11-128N14.2
100 µL
100 µg
150 µL
100 µL
100 µL
150 µL
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