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The Ras-related low molecular mass GTPases participate in signal transduction involving a variety of cellular functions, including cell-cycle progression, cellular differentiation, cytoskeletal organization, protein transport and secretion. The Ras-GTPase-activating protein (RASGAP) forms a complex with a second protein, p190, in growth factor stimulated and tyrosinekinase transformed cells. The RASGAP p190 complex may serve to couple Ras- and Rho-mediated signaling pathways. RASGAP forms an abundant SH2-mediated complex with p190 RhoGAP in cells expressing activated tyrosine kinases.
5430433H21Rik; AA517451; AU023900; CMAVM; CM-AVM; DKFZp434N071; GAP; GAP1M; GTPase-activating protein 1m; GTPase-activating protein of RAS; p120GAP; p120RASGAP; PKWS; ras GTPase-activating protein 2; RAS p21 protein activator 2; RASA; Rasa2; RASGAP
100 µL
100 µL
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