Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
SPHK1, along with SPHK2, catalyzes the phosphorylation of sphingosine producing the signaling molecule sphingosine-1-phosphate (S1P). S1P signals through G-protein coupled receptors and controls diverse cellular processes. Inhibitors of SPHKs are viewed as potential therapeutics for the treatment of cancer. SPHK1 catalyzes the phosphorylation of sphingosine to sphingosine 1 phosphate (S1P), an important signaling molecule with intra- and extracellular functions. Inside the cell S1P acts as a signaling molecule like other sphingolipid metabolites like ceramide and sphingosine. S1P has been implicated in regulating cell differentiation, calcium mobilization from intracellular stores, and apoptosis. The cell surface receptors for S1P are the EDG family of G protein-coupled receptors (S1P Receptors).
1110006G24Rik; Acetyltransferase SPHK1; RP23-193A16.4; SK 1; Sk1; SKase; Sphingosine kinase 1; SPHK; SPHK1; SPK; SPK 1; Spk1
200 µL
100 µL
100 µL
100 µg
150 µL
100 µL
100 µL
100 µL
100 µL
400 µL
100 µL
100 µg
100 µg
100 µL
100 µL
100 µg
100 µg
100 µg
100 µL
100 µg
100 µL
50 µg
100 µg
Searching for an antibody we don't offer? We make custom antibodies for specific targets, species and applications.
More than 18,000 custom antibodies created so far.
Talk to a specialist nowIf an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support