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Initiation of transcription by RNA polymerase II requires the assistance of TATA box-binding protein (TBP) and TBP-associated factors, or TAFs (e.g., TAF2B), in 2 distinct complexes, TFIID and B-TFIID. The TFIID complex is composed of TBP and more than 8 TAFs. However, the majority of TBP is present in the B-TFIID complex, which is composed of TBP and TAFII170, also called TAF172, and has DNA-dependent ATPase activity.
AI414500; AI447930; ATP-dependent helicase BTAF1; BTAF1; BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, (Mot1 homolog, S. cerevisiae); BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa; BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa (Mot1 homolog, S. cerevisiae); B-TFIID TATA-box binding protein associated factor 1; B-TFIID transcription factor-associated 170 kDa subunit; E430027O22Rik; MOT1; Mot1 homolog; RGD1564130; TAF(II)170; TAF170; TAF172; TAF-172; TAFII170; TATA-binding protein-associated factor 172; TBP-associated factor 170; TBP-associated factor 172
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